Abstract

There is a void in our current understanding of the neuropsychiatric symptoms, neurocognitive functioning, neuroimaging, and psychosocial/lifestyle factors associated with aging in African Americans. Often general health status of the participants has been left uncontrolled or poorly described, causes of dementia other than Alzheimer's Disease (AD) have not been examined, and depression and/or other psychiatric conditions have not been ruled out as influencing the results. There has been too frequent use of screening neuropsychological instruments, inattention to the potential mediating influences of lifestyle and psychosocial variables (such as religion, social support, substance use, and health), and the inclusion of African Americans as subjects in most studies has ranged from minimal to none. There has been limited attention to longitudinal aspects of changes in neuropsychiatric and neurocognitive domains as well as in quality of life (QOL) in African American senior populations.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Research Program Projects (P01)
Project #
1P01MH063357-01A1
Application #
6690937
Study Section
Special Emphasis Panel (ZMH1)
Project Start
2002-09-25
Project End
2005-07-31
Budget Start
Budget End
Support Year
1
Fiscal Year
2002
Total Cost
Indirect Cost

  Institution

Name
Charles R. Drew University of Med & Sci
Department
Type
DUNS #
785877408
City
Los Angeles
State
CA
Country
United States
Zip Code
90059

  Publications

Tafazoli, Sharwin; O'Neill, Joseph; Bejjani, Anthony et al. (2013) 1H MRSI of middle frontal gyrus in pediatric ADHD. J Psychiatr Res 47:505-12
Bejjani, Anthony; O'Neill, Joseph; Kim, John A et al. (2012) Elevated glutamatergic compounds in pregenual anterior cingulate in pediatric autism spectrum disorder demonstrated by 1H MRS and 1H MRSI. PLoS One 7:e38786
Kurth, Florian; Narr, Katherine L; Woods, Roger P et al. (2011) Diminished gray matter within the hypothalamus in autism disorder: a potential link to hormonal effects? Biol Psychiatry 70:278-82
Narr, Katherine L; Woods, Roger P; Lin, James et al. (2009) Widespread cortical thinning is a robust anatomical marker for attention-deficit/hyperactivity disorder. J Am Acad Child Adolesc Psychiatry 48:1014-22
Luders, Eileen; Narr, Katherine L; Hamilton, Liberty S et al. (2009) Decreased callosal thickness in attention-deficit/hyperactivity disorder. Biol Psychiatry 65:84-8
Strickland, Tony L; Longobardi, Paul G; Alperson, Burton L et al. (2005) Mini-Mental State and Cognistat performance in an older African American sample. Clin Neuropsychol 19:87-98