The Administrative Core (Core B) will coordinate communication and sharing of research resources related to the Program Project. The Administrative Core will be responsible for the following activities: 1. Monitoring the progress of all Projects. 2. Coordinating the submission of our non-competitive renewal application. 3. Organizing the 3 site visits by the External Review Committee. 4. Coordinating visits of the Principal Investigators every six months. 5. Coordinating monthly PI and lab member teleconference meetings between PI visits. 6. Maintain oversight of the overall and individual budgets and resolve budgetary issues that may arise during the funding period. 7. Facilitate the patient participation in the clinical studies and in obtaining biopsy and autopsy tissue.

Public Health Relevance

Core B will provide administrative support required for all components of this Program Project. The coordination of tissue sample distribution between Projects which provide an invaluable research resource. The coordination of video conferences and reviews of the project will help ensure that the appropriate progress is made by each Project, that the research remains focused on the major objectives of the Program and that maximum efforts are maintained to move the research forward.

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Program Projects (P01)
Project #
2P01NS058901-07A1
Application #
8609104
Study Section
National Institute of Neurological Disorders and Stroke Initial Review Group (NSD)
Project Start
Project End
Budget Start
2013-09-30
Budget End
2014-06-30
Support Year
7
Fiscal Year
2013
Total Cost
$37,125
Indirect Cost
$12,375
Name
University of Florida
Department
Type
DUNS #
969663814
City
Gainesville
State
FL
Country
United States
Zip Code
32611
Taliaferro, J Matthew; Vidaki, Marina; Oliveira, Ruan et al. (2016) Distal Alternative Last Exons Localize mRNAs to Neural Projections. Mol Cell 61:821-33
Freyermuth, Fernande; Rau, Frédérique; Kokunai, Yosuke et al. (2016) Splicing misregulation of SCN5A contributes to cardiac-conduction delay and heart arrhythmia in myotonic dystrophy. Nat Commun 7:11067
Scotti, Marina M; Swanson, Maurice S (2016) RNA mis-splicing in disease. Nat Rev Genet 17:19-32
Goodwin, Marianne; Mohan, Apoorva; Batra, Ranjan et al. (2015) MBNL Sequestration by Toxic RNAs and RNA Misprocessing in the Myotonic Dystrophy Brain. Cell Rep 12:1159-68
Hewitt, Angela L; Popa, Laurentiu S; Ebner, Timothy J (2015) Changes in Purkinje cell simple spike encoding of reach kinematics during adaption to a mechanical perturbation. J Neurosci 35:1106-24
Coram, Ryan J; Stillwagon, Samantha J; Guggilam, Anuradha et al. (2015) Muscleblind-like 1 is required for normal heart valve development in vivo. BMC Dev Biol 15:36
Xia, Guangbin; Gao, Yuanzheng; Jin, Shouguang et al. (2015) Genome modification leads to phenotype reversal in human myotonic dystrophy type 1 induced pluripotent stem cell-derived neural stem cells. Stem Cells 33:1829-38
Batra, Ranjan; Manchanda, Mini; Swanson, Maurice S (2015) Global insights into alternative polyadenylation regulation. RNA Biol 12:597-602
Davis, Jennifer; Salomonis, Nathan; Ghearing, Natasha et al. (2015) MBNL1-mediated regulation of differentiation RNAs promotes myofibroblast transformation and the fibrotic response. Nat Commun 6:10084
Rau, Frédérique; Lainé, Jeanne; Ramanoudjame, Laetitita et al. (2015) Abnormal splicing switch of DMD's penultimate exon compromises muscle fibre maintenance in myotonic dystrophy. Nat Commun 6:7205

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