The overall goal ofthe Administrative Core is to provide administrative support to the individual projects and cores by facilitating interactions, information sharing, statistical analysis and data integration between Projects I-III and Cores B-D. The Administrative Core will also be responsible for the scheduling of monthly meetings with all project investigators that include: 1) critiques of recent extramural publications relevant to the goals of all projects;2) presentations by project investigators, particularly when data sets are being readied for publication;3) updates on changes in the resources, essential infrastructure, and financial status of the PPG;and 4) training of graduate students and postdoctoral fellows in literature research, identifying research subjects, experimental design, trouble-shooting of experimental issues, presentation of experimental data, paper writing, submission and revisions, as well as grant writing. Graduate students and postdoctoral fellows from all PIs'labs will participate in these training events. The Administrative Core will also organize a regular schedule of invited seminar speakers that address topics of both general and specific interest to each ofthe Projects. This program will be coordinated with the Loma Linda University School of Medicine, which will help support costs associated with this visiting scientist program. The Administrative Core will also organize the external advisory committee composed of prominent extramural scientists (see Introduction) who will visit the Center for Brain Hemorrhage Research on an annual basis to review progress and project status and then issue written assessments and recommendations for continued success. The Administrative Core will contract two statisticians to participate in data processing and analysis. Finally, the Administrative Core will also coordinate the collection and compilation of all details necessary for timely filing of annual progress reports.

Public Health Relevance

The Administrative Core is instrumental in the administrative support and evaluation of the activities of this PPG, including facilitating interactions, information sharing, statistical analysis, and other administrative issues.

National Institute of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
Research Program Projects (P01)
Project #
Application #
Study Section
National Institute of Neurological Disorders and Stroke Initial Review Group (NSD)
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
Loma Linda University
Loma Linda
United States
Zip Code
Wang, Yuechun; Sherchan, Prativa; Huang, Lei et al. (2017) Naja sputatrix Venom Preconditioning Attenuates Neuroinflammation in a Rat Model of Surgical Brain Injury via PLA2/5-LOX/LTB4 Cascade Activation. Sci Rep 7:5466
Akyol, Gokce Yilmaz; Manaenko, Anatol; Akyol, Onat et al. (2017) IVIG activates Fc?RIIB-SHIP1-PIP3 Pathway to stabilize mast cells and suppress inflammation after ICH in mice. Sci Rep 7:15583
Kim, Cherine H; McBride, Devin W; Sherchan, Prativa et al. (2017) Crotalus helleri venom preconditioning reduces postoperative cerebral edema and improves neurological outcomes after surgical brain injury. Neurobiol Dis 107:66-72
Ma, Li; Manaenko, Anatol; Ou, Yi-Bo et al. (2017) Bosutinib Attenuates Inflammation via Inhibiting Salt-Inducible Kinases in Experimental Model of Intracerebral Hemorrhage on Mice. Stroke 48:3108-3116
Rolland, William B; Krafft, Paul R; Lekic, Tim et al. (2017) Fingolimod confers neuroprotection through activation of Rac1 after experimental germinal matrix hemorrhage in rat pups. J Neurochem 140:776-786
Yu, Lingyan; Lu, Zhengyang; Burchell, Sherrefa et al. (2017) Adropin preserves the blood-brain barrier through a Notch1/Hes1 pathway after intracerebral hemorrhage in mice. J Neurochem 143:750-760
McBride, Devin W; Zhang, John H (2017) Precision Stroke Animal Models: the Permanent MCAO Model Should Be the Primary Model, Not Transient MCAO. Transl Stroke Res :
Hu, Qin; Manaenko, Anatol; Bian, Hetao et al. (2017) Hyperbaric Oxygen Reduces Infarction Volume and Hemorrhagic Transformation Through ATP/NAD+/Sirt1 Pathway in Hyperglycemic Middle Cerebral Artery Occlusion Rats. Stroke 48:1655-1664
Zhang, John H; Obenaus, Andre; Liebeskind, David S et al. (2017) Recanalization, reperfusion, and recirculation in stroke. J Cereb Blood Flow Metab 37:3818-3823
Obenaus, Andre; Ng, Michelle; Orantes, Amanda M et al. (2017) Traumatic brain injury results in acute rarefication of the vascular network. Sci Rep 7:239

Showing the most recent 10 out of 52 publications