?Overall The overall goal of the Southern African Regional Center of Non-Communicable Diseases Research Excellence (RCRE) is to build the capacity and collaborations necessary to conduct regionally-relevant research related to non-communicable diseases (NCDs), initially starting with focused research in Botswana and Johannesburg, South Africa (at University of Witwatersrand) involving three priority NCDs. The three priority areas are breast cancer, hypertension, and road-traffic accident trauma. We will also identify research gaps and conduct initial data needs assessments and small pilot data strengthening projects in these areas. These areas of focus were chosen due to the high prevalence of these conditions and their substantial contribution to disease in southern Africa, and the dearth of data related to risk factors, treatment, outcomes, and other clinical/epidemiologic aspects of these conditions. We anticipate that the capacity and collaborations built as a result of this project will lead to NCD-related research of direct

Public Health Relevance

We propose establishment of a Southern African Regional Center for Research Excellence with a mission to build local capacity and diverse collaborations necessary to conduct regionally-relevant and policy-impacting research related to non-communicable diseases (NCDs). We would initially start with focused research in Botswana and Johannesburg, South Africa (at University of Witwatersrand) involving three NCDs (breast cancer, hypertension, and road-traffic accident trauma), which have been prioritized based on their high burden in southern Africa and the dearth of available data related to risk factors, treatment, outcomes, and other clinical/epidemiologic aspects. We will also identify research priorities, perform initial data needs assessments and conduct small pilot data strengthening and standardization projects in these priority areas, with the longer-term view of exploring regional data pooling. We anticipate that the proposed project would lead to NCD-related research of direct health policy relevance, and of benefit to low- and middle-income country settings in southern Africa and elsewhere.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Exploratory Grants (P20)
Project #
1P20CA210283-01
Application #
9193745
Study Section
Special Emphasis Panel (ZCA1-GRB-S (M2))
Program Officer
Silkensen, Shannon M
Project Start
2016-09-01
Project End
2018-08-31
Budget Start
2016-09-01
Budget End
2017-08-31
Support Year
1
Fiscal Year
2016
Total Cost
$239,055
Indirect Cost
$14,208
Name
Botswana-Harvard AIDS Institute
Department
Type
DUNS #
538435473
City
Gaborone
State
Country
Botswana
Zip Code
00-000
Efstathiou, Jason A; Bvochora-Nsingo, Memory; Gierga, David P et al. (2014) Addressing the growing cancer burden in the wake of the AIDS epidemic in Botswana: The BOTSOGO collaborative partnership. Int J Radiat Oncol Biol Phys 89:468-75