This core will provide the basic infrastructure that supports the operational plan and day-to-day functioning of the center. The components of the core are structured so that each support function has a circumscribed focus, which will be implemented by the director and co-director, Drs. Tapert and Schulteis. The unique expertise of Dr. Tapert in recruitment and assessment suggested a logical integration of these support functions into an Administrative Core to best service the needs of the Center.
The specific aims of this Core are: (1) to provide the administrative infrastructure across all projects and center functions;(2) to establish a uniform, validated, and reliable recruitment, screening, and assessment pathway;and (3) to provide the database and information technology infrastructure that will support efficient data analysis for all projects, communication between center members, and information distribution. By accomplishing these aims, the core will (1) enable efficient administrative support to CIDIA investigators through the provision of coordinated grants management, human subjects protections procedures, human resources assistance, and other administrative functions;(2) disseminate information about CIDIA research activities and programs within UCSD and with potential outside collaborators to encourage new collaborations and mentorship of new investigators who will do translational research relevant to interoceptive dysregulation in drug addiction;and (3) provide timely recruitment and accurate yet efficient clinical assessment functions for the human studies. Administrative functions to assure smooth operation of the Center include organizing meetings, seminars, and visits from consultants and advisors;organizing documentation to IRB, lACUC, and other entities, purchasing, and travel arrangements for Projects 1, 2, and 3. Recruitment and assessment will serve Projects 1 and 2. Information technology functions include set up and maintenance of secure and accurate data entry systems, maintenance of data security, data backup, and software maintenance for Projects 1, 2, and 3.

Public Health Relevance

Having a centralized core for administrative functions, recruitment, assessment, training, and information technology helps ensure knowledge gained from the proposed projects is shared between investigators, the broader research community, and the public.

National Institute of Health (NIH)
National Institute on Drug Abuse (NIDA)
Exploratory Grants (P20)
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Application #
Study Section
Special Emphasis Panel (ZDA1-MXS-M)
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Budget Start
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University of California San Diego
La Jolla
United States
Zip Code
Stewart, Jennifer L; Juavinett, Ashley L; May, April C et al. (2015) Do you feel alright? Attenuated neural processing of aversive interoceptive stimuli in current stimulant users. Psychophysiology 52:249-62
Paulus, Martin P; Stewart, Jennifer L (2014) Interoception and drug addiction. Neuropharmacology 76 Pt B:342-50
Gowin, Joshua L; Harle, Katia M; Stewart, Jennifer L et al. (2014) Attenuated insular processing during risk predicts relapse in early abstinent methamphetamine-dependent individuals. Neuropsychopharmacology 39:1379-87
Stewart, Jennifer L; May, April C; Poppa, Tasha et al. (2014) You are the danger: attenuated insula response in methamphetamine users during aversive interoceptive decision-making. Drug Alcohol Depend 142:110-9
Mackey, Scott; Stewart, Jennifer L; Connolly, Colm G et al. (2014) A voxel-based morphometry study of young occasional users of amphetamine-type stimulants and cocaine. Drug Alcohol Depend 135:104-11
Gowin, Joshua L; Stewart, Jennifer L; May, April C et al. (2014) Altered cingulate and insular cortex activation during risk-taking in methamphetamine dependence: losses lose impact. Addiction 109:237-47
Gowin, Joshua L; Mackey, Scott; Paulus, Martin P (2013) Altered risk-related processing in substance users: imbalance of pain and gain. Drug Alcohol Depend 132:13-21
Mackey, Scott; Paulus, Martin (2013) Are there volumetric brain differences associated with the use of cocaine and amphetamine-type stimulants? Neurosci Biobehav Rev 37:300-16
Paulus, Martin P (2013) The breathing conundrum-interoceptive sensitivity and anxiety. Depress Anxiety 30:315-20
Stewart, Jennifer L; Flagan, Taru M; May, April C et al. (2013) Young adults at risk for stimulant dependence show reward dysfunction during reinforcement-based decision making. Biol Psychiatry 73:235-41

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