Our Administrative Core (AC) will provide grants management in the following areas: 1) fiscal management;2) personnel management for the UC, Berkeley personnel;3) purchasing and property management;4) coordination with administrative personnel at Stanford School of Medicine;5) travel and reimbursement;6) compliance with IRB requirements and renewals;and 7) meeting coordination and minutes recording. The AC also consists of our planned 5-member Advisory Board (AB), whose areas of expertise are outlined in the proposal. Three meetings are anticipated with the AB: 1) at 6 months to provide critique on the Pre-Center startup;2) at 18 months to review Pre-Center progress and ideas and plans for a full-center application;and 3) at 30 months to evaluate Pre-Center accomplishments and critique of scientific and logistical issues in anticipation of a full-center application. All meetings with the AB will be documented by written notes. The AC also will provide scientific oversight and tracking of progress through monthly meetings of the entire research team, semi-annual retreats, documentation by minutes with action items to monitor progress. Oversight of the training and progress of junior faculty and graduate students and post-doctoral fellows also will be a function of the AC. Details of the plans for oversight and tracking of progress are provided in the AC write up. The AC also will have responsibility to provide timely responses to the funders in terms of submission of reports and ad hoc requests for information or informal meetings. Public Health Relevance: This Core is a required element for the application. Its function is highly relevant, since it is charged with management of all financial, personnel and logistical matters for the Pre-Center. It contains the Pre-Center's plans for the Advisory Board. Our plan for this Core shows clearly that our application represents a fully integrated Pre-Center in terms of science and administration.

Public Health Relevance

The work ofthis CHP-C is highly relevant since we are studying an area in California tha thas some of the highest ambient air pollution and pesticide exposure in the U.S. Our combined basic! immunological and epidemiological studies aim to identified how environmental toxicant effect normal fetal and early childhood developmental process that underlie diseases such as asthma and other chronic diseases of childhood.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Exploratory Grants (P20)
Project #
1P20ES018173-01
Application #
7827508
Study Section
Special Emphasis Panel (ZES1-LKB-G (P2))
Program Officer
Gray, Kimberly A
Project Start
2010-05-07
Project End
2013-01-31
Budget Start
2010-05-07
Budget End
2011-01-31
Support Year
1
Fiscal Year
2010
Total Cost
$332,913
Indirect Cost
Name
University of California Berkeley
Department
Public Health & Prev Medicine
Type
Schools of Public Health
DUNS #
124726725
City
Berkeley
State
CA
Country
United States
Zip Code
94704
Lee, Eunice Y; Lin, Jue; Noth, Elizabeth M et al. (2017) Traffic-Related Air Pollution and Telomere Length in Children and Adolescents Living in Fresno, CA: A Pilot Study. J Occup Environ Med 59:446-452
Padula, Amy M; Yang, Wei; Carmichael, Suzan L et al. (2017) Air pollution, neighborhood acculturation factors, and neural tube defects among Hispanic women in California. Birth Defects Res 109:403-422
Noth, Elizabeth M; Lurmann, Fred; Northcross, Amanda et al. (2016) Spatial and Temporal Distribution of Polycyclic Aromatic Hydrocarbons and Elemental Carbon in Bakersfield, California. Air Qual Atmos Health 9:899-908
Hew, K M; Walker, A I; Kohli, A et al. (2015) Childhood exposure to ambient polycyclic aromatic hydrocarbons is linked to epigenetic modifications and impaired systemic immunity in T cells. Clin Exp Allergy 45:238-48
Cossi, Malin; Zuta, Shkelqime; Padula, Amy M et al. (2015) Role of infant sex in the association between air pollution and preterm birth. Ann Epidemiol 25:874-6
Padula, Amy M; Balmes, John R; Eisen, Ellen A et al. (2015) Ambient polycyclic aromatic hydrocarbons and pulmonary function in children. J Expo Sci Environ Epidemiol 25:295-302
Padula, Amy M; Yang, Wei; Carmichael, Suzan L et al. (2015) Air Pollution, Neighbourhood Socioeconomic Factors, and Neural Tube Defects in the San Joaquin Valley of California. Paediatr Perinat Epidemiol 29:536-45
Padula, Amy M; Mortimer, Kathleen M; Tager, Ira B et al. (2014) Traffic-related air pollution and risk of preterm birth in the San Joaquin Valley of California. Ann Epidemiol 24:888-95e4
Padula, Amy M; Noth, Elizabeth M; Hammond, S Katharine et al. (2014) Exposure to airborne polycyclic aromatic hydrocarbons during pregnancy and risk of preterm birth. Environ Res 135:221-6
Syed, Aleena; Garcia, Marco A; Lyu, Shu-Chen et al. (2014) Peanut oral immunotherapy results in increased antigen-induced regulatory T-cell function and hypomethylation of forkhead box protein 3 (FOXP3). J Allergy Clin Immunol 133:500-10

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