The Kentucky INBRE serves a statewide mission to build a sustainable infrastructure with a capacity for biomedical and health-related research and research training. In this application, the two research intensive institutions, the University of Louisville and the University of Kentucky, will partner with our regional comprehensive affiliates including Eastern Kentucky University, Morehead State University, Northern Kentucky University and Western Kentucky University, and with a number of outreach institutions, to continue the development of a highly collaborative and successful network. The goal of our network is to build competitive research, which will serve as the foundation for excellent training of our students in the biomedical and health-related sciences. We plan to develop and grow our multi-disciplinary research network with an overarching theme of functional genomics. With an emphasis on sustainability, we will continue to fund developmental research projects for our junior investigators, while providing critical mentoring, as well as the requisite infrastructure support for genomics and bioinformatics. Our centralized genomics core facility will provide access to state-of-the-art equipment for microarray and next generation sequencing technologies along with qualified technical support. Similarly, we will continue to build a critical mass of expertise and infrastructure in bioinformatics to provide data analysis services for high content and/or high throughput data. We have built undergraduate and graduate training programs in bioinformatics. In the rapidly changing world of biomedical research, these facilities and services are essential to providing a pathway to independence for our next generation of investigators. We will provide junior faculty with ail of the tools necessary to become independent investigators, thereby building network sustainability, and at the same time provide for high quality research training experiences for our students. In summary, our strategy is designed to build a sustainable infrastructure with capacity for biomedical and health-related research arid research training. This strategy will aid the development of a highly skilled workforce in the Commonwealth of Kentucky.

National Institute of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
Exploratory Grants (P20)
Project #
Application #
Study Section
Special Emphasis Panel (ZGM1-TWD-7 (IN))
Program Officer
Arora, Krishan
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of Louisville
Anatomy/Cell Biology
Schools of Medicine
United States
Zip Code
Masterson, S P; Zhou, N; Akers, B K et al. (2018) Ultrastructural and optogenetic dissection of V1 corticotectal terminal synaptic properties. J Comp Neurol :
Monroe, Jerry D; Millay, Matthew H; Patty, Blaine G et al. (2018) The curcuminoid, EF-24, reduces cisplatin-mediated reactive oxygen species in zebrafish inner ear auditory and vestibular tissues. J Clin Neurosci 57:152-156
Brausch, Amy M; Woods, Sherry E (2018) Emotion Regulation Deficits and Nonsuicidal Self-Injury Prospectively Predict Suicide Ideation in Adolescents. Suicide Life Threat Behav :
Colter, Breann T; Garber, Helen Frances; Fleming, Sheila M et al. (2018) Ahr and Cyp1a2 genotypes both affect susceptibility to motor deficits following gestational and lactational exposure to polychlorinated biphenyls. Neurotoxicology 65:125-134
Marczinski, Cecile A; Stamates, Amy L; Maloney, Sarah F (2018) Differential development of acute tolerance may explain heightened rates of impaired driving after consumption of alcohol mixed with energy drinks versus alcohol alone. Exp Clin Psychopharmacol 26:147-155
Lee, Juyeun; Park, Nogi; Park, Joo Youn et al. (2018) Induction of Immunosuppressive CD8+CD25+FOXP3+ Regulatory T Cells by Suboptimal Stimulation with Staphylococcal Enterotoxin C1. J Immunol 200:669-680
King, Rodney A; Perez, Meghan T (2018) Sequence Analysis of a Hybrid HK022/? Bacteriophage and the Precise Identification of the ?b515 and ?b519 Deletion Endpoints. Microbiol Resour Announc 7:
Gonzalez, O A; Kirakodu, S; Novak, M J et al. (2018) Comparative analysis of microbial sensing molecules in mucosal tissues with aging. Immunobiology 223:279-287
Ha, Dat Thinh; Ghosh, Sthitodhi; Ahn, Chong H et al. (2018) Pathogen-specific DNA sensing with engineered zinc finger proteins immobilized on a polymer chip. Analyst 143:4009-4016
Song, Ming; Li, Xiaohong; Zhang, Xiang et al. (2018) Dietary copper-fructose interactions alter gut microbial activity in male rats. Am J Physiol Gastrointest Liver Physiol 314:G119-G130

Showing the most recent 10 out of 193 publications