This proposal continues the development of the Nevada IDeA Network of Biomedical Research Excellence (NV INBRE) initiated in 2005. During the previous funding periods we established an administrative network linking the major research and education institutions in Nevada, we supported researchers and statewide research service cores, and we increased the science and technology knowledge of Nevada's workforce through a Biomedical Student Pipeline that mentored students, including students under-represented in biomedical science. In this renewal proposal, we build on these accomplishments by developing new programs supporting research investigating Cell Growth and Differentiation, by expanding our student development pipeline, and by bringing new institutions into our network. The project will (1) implement a Developmental Research Project (DRP) and Pilot Grant (PG) Program to increase research investigating Cell Growth and Differentiation, (2) continue to provide resources and services provided by the Bioinformatics Core, and (3) expand the Biomedical Student Pipeline creating the Outreach / Diversity / Pipeline (ODP) Program to prepare students enrolled in 2- and 4-year programs for education and careers in research investigating Cell Growth and Differentiation. In addition, the NV INBRE will renovate laboratory space at Nevada State College to create a facility that will support authentic research investigating Cell Growth and Differentiation by their undergraduate students and faculty. All activities will be coordinated by an Administrative Core with direct responsibilit for compliance, managing program funding, facilitating communication in the network, overseeing all research activities, coordinating training and mentoring for faculty and students, and performing assessment, tracking, and evaluation.

Public Health Relevance

This project continues the development of the Nevada IDeA Network of Biomedical Research Excellence (NV INBRE) initiated in 2005. The project will link all Nevada public universities and colleges and the state' only private liberal arts college in a network to share expertise and resources. We will increase biomedical research in the state by funding new research projects, supporting a Bioinformatics Core that provides computational power and support for genome analysis, and mentoring students enrolled in 2- and 4-year programs for education and careers in research investigating Cell Growth and Differentiation. In addition, the NV INBRE will renovate laboratory space at Nevada State College to enable students to participate in biomedical research projects.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Exploratory Grants (P20)
Project #
3P20GM103440-14A1S1
Application #
9320302
Study Section
Special Emphasis Panel (ZGM1-RCB-A (IN))
Program Officer
Arora, Krishan
Project Start
2001-09-01
Project End
2021-03-31
Budget Start
2016-04-01
Budget End
2017-03-31
Support Year
14
Fiscal Year
2016
Total Cost
$385,443
Indirect Cost
$91,075
Name
University of Nevada Reno
Department
Physiology
Type
Schools of Medicine
DUNS #
146515460
City
Reno
State
NV
Country
United States
Zip Code
89557
Clements-Nolle, Kristen; Lensch, Taylor; Baxa, Amberlee et al. (2017) Sexual Identity, Adverse Childhood Experiences, and Suicidal Behaviors. J Adolesc Health :
Yang, Yifang; Koirala, Bimal; Sanchez, Lucia A et al. (2017) Structure-Activity Relationships of the Competence Stimulating Peptides (CSPs) in Streptococcus pneumoniae Reveal Motifs Critical for Intra-group and Cross-group ComD Receptor Activation. ACS Chem Biol 12:1141-1151
Nadeau, J A; Petereit, J; Tillett, R L et al. (2017) Comparative transcriptomics of mountain pine beetle pheromone-biosynthetic tissues and functional analysis of CYP6DE3. BMC Genomics 18:311
McBrayer, Dominic N; Gantman, Brooke K; Cameron, Crissey D et al. (2017) An Entirely Solid Phase Peptide Synthesis-Based Strategy for Synthesis of Gelatinase Biosynthesis-Activating Pheromone (GBAP) Analogue Libraries: Investigating the Structure-Activity Relationships of the Enterococcus faecalis Quorum Sensing Signal. Org Lett 19:3295-3298
Kim, Minkyung; Fontelonga, Tatiana M; Lee, Clare H et al. (2017) Motor axons are guided to exit points in the spinal cord by Slit and Netrin signals. Dev Biol 432:178-191
Kim, Minkyung; Bjorke, Brielle; Mastick, Grant S (2017) Motor neuron migration and positioning mechanisms: New roles for guidance cues. Semin Cell Dev Biol :
Zhang, Hua; Jiang, Tao; Shan, Guogen et al. (2017) Gaussian network model can be enhanced by combining solvent accessibility in proteins. Sci Rep 7:7486
Das Banerjee, Tania; Dagda, Raul Y; Dagda, Marisela et al. (2017) PINK1 regulates mitochondrial trafficking in dendrites of cortical neurons through mitochondrial PKA. J Neurochem 142:545-559
Yobi, Abou; Schlauch, Karen A; Tillett, Richard L et al. (2017) Sporobolus stapfianus: Insights into desiccation tolerance in the resurrection grasses from linking transcriptomics to metabolomics. BMC Plant Biol 17:67
Raymond, James A; Morgan-Kiss, Rachael (2017) Multiple ice-binding proteins of probable prokaryotic origin in an Antarctic lake alga, Chlamydomonas sp. ICE-MDV (Chlorophyceae). J Phycol 53:848-854

Showing the most recent 10 out of 134 publications