This proposal continues the development of the Nevada IDeA Network of Biomedical Research Excellence (NV INBRE) initiated in 2005. During the previous funding periods we established an administrative network linking the major research and education institutions in Nevada, we supported researchers and statewide research service cores, and we increased the science and technology knowledge of Nevada's workforce through a Biomedical Student Pipeline that mentored students, including students under-represented in biomedical science. In this renewal proposal, we build on these accomplishments by developing new programs supporting research investigating Cell Growth and Differentiation, by expanding our student development pipeline, and by bringing new institutions into our network. The project will (1) implement a Developmental Research Project (DRP) and Pilot Grant (PG) Program to increase research investigating Cell Growth and Differentiation, (2) continue to provide resources and services provided by the Bioinformatics Core, and (3) expand the Biomedical Student Pipeline creating the Outreach / Diversity / Pipeline (ODP) Program to prepare students enrolled in 2- and 4-year programs for education and careers in research investigating Cell Growth and Differentiation. In addition, the NV INBRE will renovate laboratory space at Nevada State College to create a facility that will support authentic research investigating Cell Growth and Differentiation by their undergraduate students and faculty. All activities will be coordinated by an Administrative Core with direct responsibilit for compliance, managing program funding, facilitating communication in the network, overseeing all research activities, coordinating training and mentoring for faculty and students, and performing assessment, tracking, and evaluation.
This project continues the development of the Nevada IDeA Network of Biomedical Research Excellence (NV INBRE) initiated in 2005. The project will link all Nevada public universities and colleges and the state' only private liberal arts college in a network to share expertise and resources. We will increase biomedical research in the state by funding new research projects, supporting a Bioinformatics Core that provides computational power and support for genome analysis, and mentoring students enrolled in 2- and 4-year programs for education and careers in research investigating Cell Growth and Differentiation. In addition, the NV INBRE will renovate laboratory space at Nevada State College to enable students to participate in biomedical research projects.
|Blanco, Luz P; Payne, Bryan L; Feyertag, Felix et al. (2018) Proteins of generalist and specialist pathogens differ in their amino acid composition. Life Sci Alliance 1:e201800017|
|Koirala, Bimal; Lin, Jingjun; Lau, Gee W et al. (2018) Development of a Dominant Negative Competence-Stimulating Peptide (dnCSP) that Attenuates Streptococcus pneumoniae Infectivity in a Mouse Model of Acute Pneumonia. Chembiochem 19:2380-2386|
|Mull, Ryan W; Harrington, Anthony; Sanchez, Lucia A et al. (2018) Cyclic Peptides that Govern Signal Transduction Pathways: From Prokaryotes to Multi-Cellular Organisms. Curr Top Med Chem 18:625-644|
|Calfee, Gregory; Danger, Jessica L; Jain, Ira et al. (2018) Identification and Characterization of Serotype-Specific Variation in Group A Streptococcus Pilus Expression. Infect Immun 86:|
|Zhang, Yunfang; Zhang, Xudong; Shi, Junchao et al. (2018) Dnmt2 mediates intergenerational transmission of paternally acquired metabolic disorders through sperm small non-coding RNAs. Nat Cell Biol 20:535-540|
|Abdul, Ata Ur Rahman Mohammed; De Silva, Bhagya; Gary, Ronald K (2018) The GSK3 kinase inhibitor lithium produces unexpected hyperphosphorylation of ?-catenin, a GSK3 substrate, in human glioblastoma cells. Biol Open 7:|
|Pinheiro, Paulo S; Callahan, Karen E; Boscoe, Francis P et al. (2018) Cancer Site-Specific Disparities in New York, Including the 1945-1965 Birth Cohort's Impact on Liver Cancer Patterns. Cancer Epidemiol Biomarkers Prev 27:917-927|
|O'Brien, Kristin M; Rix, Anna S; Egginton, Stuart et al. (2018) Cardiac mitochondrial metabolism may contribute to differences in thermal tolerance of red- and white-blooded Antarctic notothenioid fishes. J Exp Biol 221:|
|Yang, Yifang; Cornilescu, Gabriel; Tal-Gan, Yftah (2018) Structural Characterization of Competence-Stimulating Peptide Analogues Reveals Key Features for ComD1 and ComD2 Receptor Binding in Streptococcus pneumoniae. Biochemistry 57:5359-5369|
|Harrington, Anthony; Tal-Gan, Yftah (2018) Identification of Streptococcus gallolyticus subsp. gallolyticus (Biotype I) Competence-Stimulating Peptide Pheromone. J Bacteriol 200:|
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