North Dakota is a state with a large land mass and a small, widely dispersed rural population. These characteristics motivated the ND INBRE to focus narrowly and aggressively on providing opportunities for the State's under-served students to participate in undergraduate and K-12 activities that would stimulate interest in joining the Nation's health professional pipeline. To date, the ND INBRE has formed effective and productive partnerships with all the state-supported four year primarily undergraduate institutions (PUIs) and all Tribal Colleges (TCUs) located within the borders of ND. In addition, the ND INBRE provides registration for all junior and senior high schools as encouragement for their students to participate in the regional, state, and national Science and Engineering Fair program. These partnerships are enhanced by successful efforts of the ND INBRE to improve and provide infrastructure to the research intensive universities (RlUs) and the PUI and TCU partners. These efforts will be continued in the current funding cycle with the additional participation of our community colleges in the summer undergraduate research program. The emphasis on undergraduate research will continue as the ND INBRE will fund 7 Research Development Grants at the 4 PUI institutions, 5 Student Powered Pilot Grants at the 5 Tribal Colleges, and 50 Summer Undergraduate Summer Research Fellowships primarily at the RIU institutions. The Transfer Stars program will encourage American Indian students graduating from 2 yr TCUs to complete their baccalaureate degrees and the Science and Engineering Fair program will encourage undergraduate enrollment in STEM programs at all ND institutions of higher learning. Following the award of the PUI and TCU research programs, competitive support for mentors and core infrastructure will be provided to the RIU institutions. The ND INBRE proposes to continue its outstanding performance in serving North Dakota's development of the next generation of biomedical research scientists and health professionals.

Public Health Relevance

The stimulation of undergraduate student interest in pursuing careers in biomedical research and the health professions is essential for the future health and well-being of all citizens. An important means of fostering such interest is to engage K-12 and undergraduate students in biomedical, behavioral and translational research. The means to foster this interest is provided by the IDeA program in general and the INBRE program in particular.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Exploratory Grants (P20)
Project #
2P20GM103442-14
Application #
8687087
Study Section
Special Emphasis Panel (ZGM1-TWD-3 (IN))
Program Officer
Caldwell, Sheila
Project Start
2001-09-24
Project End
2019-04-30
Budget Start
2014-08-01
Budget End
2015-04-30
Support Year
14
Fiscal Year
2014
Total Cost
$3,395,637
Indirect Cost
$847,415
Name
University of North Dakota
Department
Pathology
Type
Schools of Medicine
DUNS #
102280781
City
Grand Forks
State
ND
Country
United States
Zip Code
58202
Collette, Katie M; Zhou, Xu Dong; Amoth, Haley M et al. (2014) Long-term ?1B-adrenergic receptor activation shortens lifespan, while ?1A-adrenergic receptor stimulation prolongs lifespan in association with decreased cancer incidence. Age (Dordr) 36:9675
Mehus, Aaron A; Muhonen, Wallace W; Garrett, Scott H et al. (2014) Quantitation of human metallothionein isoforms: a family of small, highly conserved, cysteine-rich proteins. Mol Cell Proteomics 13:1020-33
Garrett, Scott H; Somji, Seema; Sens, Donald A et al. (2014) Prediction of the number of activated genes in multiple independent Cd(+2)- and As(+3)-induced malignant transformations of human urothelial cells (UROtsa). PLoS One 9:e85614
Mei, Yang; Su, Minfei; Soni, Gaurav et al. (2014) Intrinsically disordered regions in autophagy proteins. Proteins 82:565-78
Xie, Linglin; Fu, Qiang; Ortega, Teresa M et al. (2014) Overexpression of IL-10 in C2D macrophages promotes a macrophage phenotypic switch in adipose tissue environments. PLoS One 9:e86541
Wang, Sheng-zhi; Ibrahim, Leena A; Kim, Young J et al. (2013) Slit/Robo signaling mediates spatial positioning of spiral ganglion neurons during development of cochlear innervation. J Neurosci 33:12242-54
Xie, Linglin; Wang, Weiqun (2013) Weight control and cancer preventive mechanisms: role of insulin growth factor-1-mediated signaling pathways. Exp Biol Med (Maywood) 238:127-32
Xiong, Xiaorui R; Liang, Feixue; Li, Haifu et al. (2013) Interaural level difference-dependent gain control and synaptic scaling underlying binaural computation. Neuron 79:738-53
Clarke, Kaitlin; Yang, Yi; Marsh, Ronald et al. (2013) Comparative analysis of de novo transcriptome assembly. Sci China Life Sci 56:156-62
Garrett, Scott H; Clarke, Kaitlin; Sens, Donald A et al. (2013) Short and long term gene expression variation and networking in human proximal tubule cells when exposed to cadmium. BMC Med Genomics 6 Suppl 1:S2