The overall goal of this core is to make equipment and expertise available to our Jls and other Tulane Center for Aging members that will allow them to be more productive investigators. This will provide capabilities to our investigators that either allows them to compete effectively with other investigators, or ideally allows them to carry out experiments more efficiently, or that are even not possible, at other institutions. The core facilities at the Tulane Center for Aging are an evolving entity. We do not intend to duplicate instrumentation readily accessible at other locations at Tulane or to provide resources that are more easily available to our investigators locally in their departments. The genomics core is an existing unit forged from equipment placed in the core by Dr. Jazwinski and purchased directly by the university. The lllumina Bead Station is the unique instrument in the Core that provides important capabilities for genetic and gene expression analyses. Our Jl's have broad based needs for DNA sequencing, genotyping, and gene expression analysis services that can be met by this core. They also need the bioinformatics and biostatistics support to analyze their data. We support both of these needs in our research core.
Our specific aims are: 1. To provide access, training, maintenance, and technical support for DNA sequencing, gene expression analysis, and high-throughput genotyping and gene expression services in our core, based on the high quality instrumentation available to our faculty. 2. To provide bioinformatics and biostatistics support to our investigators for analysis of the data they acquire in our core facility.

National Institute of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
Exploratory Grants (P20)
Project #
Application #
Study Section
Special Emphasis Panel (ZRR1-RI-B)
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
Tulane University
New Orleans
United States
Zip Code
Zhang, Yanqing; Fava, Genevieve E; Wang, Hongjun et al. (2016) PAX4 Gene Transfer Induces α-to-β Cell Phenotypic Conversion and Confers Therapeutic Benefits for Diabetes Treatment. Mol Ther 24:251-60
Burks, Hope E; Phamduy, Theresa B; Azimi, Mohammad S et al. (2016) Laser Direct-Write Onto Live Tissues: A Novel Model for Studying Cancer Cell Migration. J Cell Physiol 231:2333-8
Boraas, Liana C; Ahsan, Tabassum (2016) Lack of vimentin impairs endothelial differentiation of embryonic stem cells. Sci Rep 6:30814
Zhou, Xiang; Hao, Qian; Liao, Peng et al. (2016) Nerve growth factor receptor negates the tumor suppressor p53 as a feedback regulator. Elife 5:
Mock, Jeffrey R; Foundas, Anne L; Golob, Edward J (2016) Cortical activity during cued picture naming predicts individual differences in stuttering frequency. Clin Neurophysiol 127:3093-101
Yariswamy, Manjunath; Yoshida, Tadashi; Valente, Anthony J et al. (2016) Cardiac-restricted Overexpression of TRAF3 Interacting Protein 2 (TRAF3IP2) Results in Spontaneous Development of Myocardial Hypertrophy, Fibrosis, and Dysfunction. J Biol Chem 291:19425-36
Sloas, David C; Stewart, Scott A; Sweat, Richard S et al. (2016) Estimation of the Pressure Drop Required for Lymph Flow through Initial Lymphatic Networks. Lymphat Res Biol 14:62-9
Quijano, Lina M; Lynch, Kristen M; Allan, Christopher H et al. (2016) Looking Ahead to Engineering Epimorphic Regeneration of a Human Digit or Limb. Tissue Eng Part B Rev 22:251-62
Jiang, James C; Stumpferl, Stefan W; Tiwari, Anurag et al. (2016) Identification of the Target of the Retrograde Response that Mediates Replicative Lifespan Extension in Saccharomyces cerevisiae. Genetics 204:659-673
Wolfe, Russell P; Guidry, Julia B; Messina, Stephanie L et al. (2016) Applying Shear Stress to Pluripotent Stem Cells. Methods Mol Biol 1341:377-89

Showing the most recent 10 out of 50 publications