Abstract

The general aim of the Biostatistics Core is to provide statistical support and mentorship to the researchers in the Centerfor Basic and Translafional Stroke Research (CBTSR), inifially supported by the COBRE mechanism if funded. Statisfical support will be comprised of assistance in study design, data analysis, and data management. The availability of the Biostatisfics Core will greatly aid the scientists in the design and analysis of all project studies.
The specific aims of each of the research proposals contained in this COBRE grant will be met by collaborafing with Biostafistics Core members, not merely consulting. The availability of the Biostatistics Core will remove the burden of analysis from the scienfists. Given the nature of the Biostatistics Core, all five projects will utilize Core services as needed for design and analytical assistance.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Exploratory Grants (P20)
Project #
1P20GM109098-01
Application #
8663439
Study Section
Special Emphasis Panel (ZGM1-TWD-C (C1))
Project Start
Project End
Budget Start
2014-09-08
Budget End
2015-05-31
Support Year
1
Fiscal Year
2014
Total Cost
$59,740
Indirect Cost
$19,646

  Institution

Name
West Virginia University
Department
Type
DUNS #
191510239
City
Morgantown
State
WV
Country
United States
Zip Code
26506

  Publications

Robinson, Andria R; Yousefzadeh, Matthew J; Rozgaja, Tania A et al. (2018) Spontaneous DNA damage to the nuclear genome promotes senescence, redox imbalance and aging. Redox Biol 17:259-273
Branyan, Kayla W; Devallance, Evan R; Lemaster, Kent A et al. (2018) Role of Chronic Stress and Exercise on Microvascular Function in Metabolic Syndrome. Med Sci Sports Exerc 50:957-966
Schmidt, Heidi M; Kelley, Eric E; Straub, Adam C (2018) The impact of xanthine oxidase (XO) on hemolytic diseases. Redox Biol 21:101072
Povroznik, Jessica M; Ozga, Jenny E; Vonder Haar, Cole et al. (2018) Executive (dys)function after stroke: special considerations for behavioral pharmacology. Behav Pharmacol 29:638-653
Sheppard, Jordan G; Frazier, Keely R; Saralkar, Pushkar et al. (2018) Disulfiram-based disulfides as narrow-spectrum antibacterial agents. Bioorg Med Chem Lett 28:1298-1302
Sprenkle, Neil T; Lahiri, Anirudhya; Simpkins, James W et al. (2018) Endoplasmic reticulum stress is transmissible in vitro between cells of the central nervous system. J Neurochem :
O'Connell, Grant C; Treadway, Madison B; Tennant, Connie S et al. (2018) Shifts in Leukocyte Counts Drive the Differential Expression of Transcriptional Stroke Biomarkers in Whole Blood. Transl Stroke Res :
Brooks, Steven; Brnayan, Kayla W; DeVallance, Evan et al. (2018) Psychological stress-induced cerebrovascular dysfunction: the role of metabolic syndrome and exercise. Exp Physiol 103:761-776
Brichacek, Allison L; Brown, Candice M (2018) Alkaline phosphatase: a potential biomarker for stroke and implications for treatment. Metab Brain Dis :
Shumar, Stephanie A; Kerr, Evan W; Geldenhuys, Werner J et al. (2018) Nudt19 is a renal CoA diphosphohydrolase with biochemical and regulatory properties that are distinct from the hepatic Nudt7 isoform. J Biol Chem 293:4134-4148

Showing the most recent 10 out of 61 publications