The general aim of the Biostatistics Core is to provide statistical support and mentorship to the researchers in the Centerfor Basic and Translafional Stroke Research (CBTSR), inifially supported by the COBRE mechanism if funded. Statisfical support will be comprised of assistance in study design, data analysis, and data management. The availability of the Biostatisfics Core will greatly aid the scientists in the design and analysis of all project studies.
The specific aims of each of the research proposals contained in this COBRE grant will be met by collaborafing with Biostafistics Core members, not merely consulting. The availability of the Biostatistics Core will remove the burden of analysis from the scienfists. Given the nature of the Biostatistics Core, all five projects will utilize Core services as needed for design and analytical assistance.
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|Engler-Chiurazzi, E B; Singh, M; Simpkins, J W (2016) From the 90's to now: A brief historical perspective on more than two decades of estrogen neuroprotection. Brain Res 1633:96-100|
|Engler-Chiurazzi, E B; Brown, C M; Povroznik, J M et al. (2016) Estrogens as neuroprotectants: Estrogenic actions in the context of cognitive aging and brain injury. Prog Neurobiol :|
|Engler-Chiurazzi, Elizabeth B; Covey, Douglas F; Simpkins, James W (2016) A novel mechanism of non-feminizing estrogens in neuroprotection. Exp Gerontol :|
|Petrone, Ashley B; O'Connell, Grant C; Regier, Michael D et al. (2016) The Role of Arginase 1 in Post-Stroke Immunosuppression and Ischemic Stroke Severity. Transl Stroke Res 7:103-10|
|Sarkar, S; Jun, S; Rellick, S et al. (2016) Expression of microRNA-34a in Alzheimer's disease brain targets genes linked to synaptic plasticity, energy metabolism, and resting state network activity. Brain Res 1646:139-51|
|Hu, Heng; Doll, Danielle N; Sun, Jiahong et al. (2016) Mitochondrial Impairment in Cerebrovascular Endothelial Cells is Involved in the Correlation between Body Temperature and Stroke Severity. Aging Dis 7:14-27|
|Engler-Chiurazzi, Elizabeth B; Stapleton, Phoebe A; Stalnaker, Jessica J et al. (2016) Impacts of prenatal nanomaterial exposure on male adult Sprague-Dawley rat behavior and cognition. J Toxicol Environ Health A 79:447-52|
|Sun, Jiahong; Hu, Heng; Ren, Xuefang et al. (2016) Tert-butylhydroquinone compromises survival in murine experimental stroke. Neurotoxicol Teratol 54:15-21|
|DeVallance, E; Fournier, S; Lemaster, K et al. (2016) The effects of resistance exercise training on arterial stiffness in metabolic syndrome. Eur J Appl Physiol 116:899-910|
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