Collaborative research challenges. The RMC is charged with creating solutions to the inevitable research ?challenges inherent in collaboratively designed studies, thereby, potentially helping the field increase the ' number of research studies which examine the process of service delivery and outcomes of child mental health services that are co-designed by relevant stakeholders. Specific goals of the RMC are to: a) assist in preparing urban services researchers to effectively conduct collaborative studies (thus, RMC will support CCCR pilot research studies;f) consult with CCCR investigators on current and planned collaborative research studies);b) refine and develop statistical approaches to help stakeholders make decisions'regarding which existing and emerging evidence-based services may be relevant for their community or client population (issues ofgeneralizeability);c) create multi-step approaches to the design of evidence-informed service delivery that allows for maximum collaborative input and which can be continuously informed by preliminary, qualitative and quantitative and;d) expand research design options which are sufficiently rigorous to produce useful knowledge, but also which have built in flexibility to respond to constraints and preferences. ', . More specifically, the Core must respond to necessarv modifications in designs and.methods based upon the collaborative input of stakeholders bv developing alternative approaches that can support the conduct of rigorous sen/ices research successfullv within """"""""real worid"""""""" settings and communities, in these settings, the, ? well-controlled, tightly constrained aspects of traditional designs may not be feasible. Random assignment to . no treatment may not be acceptable. Moreover, given the- importance of understanding the impact'of ecological factors in real world settings, and the complexity of these multiple interacting, but """"""""uncontrolled"""""""" variables, analytic methods and research designs must explore new ways to fully capture the impact of new delivery models on utilization, ?'. / ''. implementation and multi-level outcomes. These methods must take into account that-it frequently is hot just a characteristic of a child that is the object of study, but the contextually- and historically-shaped transactions between the child and the larger environment (e.g. family, peers). Further, these methods must be sufficiently robust to address common threats in urban studies (e.g. missing data). 'i - Next, if the research addresses topics tapping racially sensitive information, modifications in research J procedures and staffing mav be necessarv (e.g., development of methods to train and supervise community inten/iewers). Further, instruments and methods that can capture the role of racial and ethnic perspectives, group identify, inner-city context must be further refined. .; Given tlie research obstacles inevitably confronted by CCCR investigators within """"""""real world"""""""" child sen/ing settings, RMC Core leadership needs to bring substantial expertise in assisting new investigators with strategies that maintain the integritv ofthe research while simultaneously addressing any or all ofthe following: difficulty with recruitmerit, trackirig, mobility, reteritiori. coriflict with key stakeholders regarding sampling; design, measurement, interpretatiori arid dissemiriation of findings. Finally, the RMC will concentrate on advancing methods related to understanding the likelihood that an existing evidence-based sen/ice will generalize to new populations of interest, particularly youth and families, impacted by poverty and a range of urban stressors. However, even if an existing evidence-based service appears promising for urban youth and their families, collaboration with key stakeholders (e.g. youth, adult caregivers, providers, communities) is still necessary to facilitate """"""""buy in,"""""""" enhance cultural arid contextual relevance and maximize likelihood of high external validity. Traditional efficacy studies have generally emphasized internal validity, with the assumption that once a service has been proveri efficacious, theri it cari be disseminated to practice settings with relatively few modifications. This has proven to be a faulty assumption as so many eviderice-based child mental health ' services have failed to be implemented and sustairied withiri """"""""real worid practice settings: (Weiss et al., 2005; Hoagwood et al., 2004). Thus, the RMC will pay particular attention to issues related to the appropriateness of transporting existing evidence-based interventioris to urbari coritexts with specific emphasis ori examiriirig issues related to gerieralizability. An important starting point for the Research Methods Core of the CCCR is that a child mental health service inriovation must be optimized to be practical, flexible to adjust to settirig constraints, acceptable and sustainable. Funding from the CCCR will support Center faculty to embark on collaborative pil.ot research studies seen by many traditional investigators as """"""""too messy.ortoo time consumirig"""""""" iri an effort to balarice and optimize both iriternal and exterrial validity. Further, RMC cdre leadership is prepared to fully partner with, CCCR irivestigators in the desigri, implemeritatiori arid examiriation of collaboratively designed studies.

National Institute of Health (NIH)
National Institute of Mental Health (NIMH)
Exploratory Grants (P20)
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Special Emphasis Panel (ZMH1-ERB-B)
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Icahn School of Medicine at Mount Sinai
New York
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Olin, Su-Chin Serene; Chor, Ka Ho Brian; Weaver, James et al. (2015) Multilevel predictors of clinic adoption of state-supported trainings in children's services. Psychiatr Serv 66:484-90
Small, Latoya; Jackson, Jerrold; Gopalan, Geetha et al. (2015) Meeting the complex needs of urban youth and their families through the 4Rs 2Ss Family Strengthening Program: The ""real world"" meets evidence-informed care. Res Soc Work Pract 25:433-45
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Marcus, Sue M; Lu, Bo; Lim, Sungwoo et al. (2013) Suicide attempts in patients with bipolar disorder tend to precede, not follow, initiation of antiepileptic drugs. J Clin Psychiatry 74:630-1
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Chacko, Anil; Uderman, Jodi Z; Zwilling, Amanda (2013) Lessons Learned in Enhancing Behavioral Parent Training for High-Risk Families of Youth with ADHD. ADHD Rep 21:6-11
Marcus, Sue M; Stuart, Elizabeth A; Wang, Pei et al. (2012) Estimating the causal effect of randomization versus treatment preference in a doubly randomized preference trial. Psychol Methods 17:244-54

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