This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. The Vascular and Cardiac Function Core provides space, facilities, supervision and training for COBRE investigators who use animal models of cardiovascular disease and/or in vivo technology to answer specific aims outlined in their research projects. This Core is under the direction of Dr. Kurt Varner, who has over 20 years of experience in cardiovascular physiology and pharmacology. Dr. Varner works closely with the junior and developing investigators in experimental design and data analysis and interpretation. The core provides services for the design and development of new animal models for cardiovascular research. The services of the Core encompass;1) ultrasound imaging, 2) radio telemetry, 3) cardiac pressure-volume analysis, 4) microinjection, 5) sympathetic nerve recording, 6) tissue collection, and 7) blood flow analysis.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Exploratory Grants (P20)
Project #
5P20RR018766-09
Application #
8360495
Study Section
Special Emphasis Panel (ZRR1-RI-6 (01))
Project Start
2011-07-01
Project End
2012-06-30
Budget Start
2011-07-01
Budget End
2012-06-30
Support Year
9
Fiscal Year
2011
Total Cost
$167,894
Indirect Cost
Name
Louisiana State Univ Hsc New Orleans
Department
Pharmacology
Type
Schools of Medicine
DUNS #
782627814
City
New Orleans
State
LA
Country
United States
Zip Code
70112
Li, Li; Bai, Shi; Sheline, Christian T (2017) hZnT8 (Slc30a8) Transgenic Mice That Overexpress the R325W Polymorph Have Reduced Islet Zn2+ and Proinsulin Levels, Increased Glucose Tolerance After a High-Fat Diet, and Altered Levels of Pancreatic Zinc Binding Proteins. Diabetes 66:551-559
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