PROJECT suiViiViARY: The goal ofthe Education, Recruitment and Retention Core ofthe Penn ADCC ~ Core E - - is to generate and properiy use resources and personnel to (1) develop, implement, and monitor recruitment and retention programs that assure research proceeds in a time- and cost-efificient manner;(2) train researchers and staff in skills in state-of-the-art techniques in clinical assessment, and recruitment and retention;and (3) give researchers, staff, patients, and families relevant knowledge on mild cognitive impairment (MCI), Alzheimer's disease (AD) and related diseases. Core E has developed a multi-disciplinary, highly collaborative, and productive team that has in-house talent and resources to design, produce, and disseminate novel materials for recruitment, retention, and education. The Core is well integrated into the ADCC cores and leadership, as well as the national network of ADC's, ADEAR, and the ADCS. The crux of the Education Core's significance is persuasive communication. The core's key resources are its five personnel led by Jason Kariawish (who is also associate director ofthe Clinical Core), and its materials and methods: the center's web page, bilingual resource center, the ADCC newsletter (InSight), and bilingual informational and support materials. To achieve its goal, Core E has the following three specific aims: #1: To assist investigators in developing research strategies to recruit and retain subjects for research protocols and clinical trials on AD and related disorders, with a special emphasis on the Latino community of North Philadelphia and the African- American community of West Philadelphia. #2: To support the development of health care professionals' clinical and clinical research skills related to AD, other neurodegenerative diseases and their prodromal phases (e.g. MCI). #3: To spearhead effective outreach programs that will publicize the ADCC and the PMC, educate families and caregivers, and build and maintain collaborative and trusting relationships with patients and families who participate in the ADCC longitudinal cohort, especially those in the Latino community of North Philadelphia and the African-American community of West Philadelphia.

Public Health Relevance

Core E is highly relevant to the continued success ofthe Penn ADCC because of its key role in staff training, recruitment and retention, and outreach. These activities are critical to continued success in research to develop better diagnostic and treatment methods. The Core has close and regular collaborations with the Clinical and Administrative Cores. The integration of Clinical and Education cores leadership is of particular value.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Center Core Grants (P30)
Project #
5P30AG010124-24
Application #
8688105
Study Section
Special Emphasis Panel (ZAG1)
Project Start
Project End
Budget Start
2014-07-01
Budget End
2015-06-30
Support Year
24
Fiscal Year
2014
Total Cost
Indirect Cost
Name
University of Pennsylvania
Department
Type
DUNS #
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Stites, Shana D; Harkins, Kristin; Rubright, Jonathan D et al. (2018) Relationships Between Cognitive Complaints and Quality of Life in Older Adults With Mild Cognitive Impairment, Mild Alzheimer Disease Dementia, and Normal Cognition. Alzheimer Dis Assoc Disord 32:276-283
Hansson, Oskar; Seibyl, John; Stomrud, Erik et al. (2018) CSF biomarkers of Alzheimer's disease concord with amyloid-? PET and predict clinical progression: A study of fully automated immunoassays in BioFINDER and ADNI cohorts. Alzheimers Dement 14:1470-1481
Wang, Tingyan; Qiu, Robin G; Yu, Ming (2018) Predictive Modeling of the Progression of Alzheimer's Disease with Recurrent Neural Networks. Sci Rep 8:9161
Barupal, Dinesh Kumar; Fan, Sili; Wancewicz, Benjamin et al. (2018) Generation and quality control of lipidomics data for the alzheimer's disease neuroimaging initiative cohort. Sci Data 5:180263
Lleó, Alberto; Irwin, David J; Illán-Gala, Ignacio et al. (2018) A 2-Step Cerebrospinal Algorithm for the Selection of Frontotemporal Lobar Degeneration Subtypes. JAMA Neurol 75:738-745
Agogo, George O; Ramsey, Christine M; Gnjidic, Danijela et al. (2018) Longitudinal associations between different dementia diagnoses and medication use jointly accounting for dropout. Int Psychogeriatr 30:1477-1487
Martini-Stoica, Heidi; Cole, Allysa L; Swartzlander, Daniel B et al. (2018) TFEB enhances astroglial uptake of extracellular tau species and reduces tau spreading. J Exp Med 215:2355-2377
He, Zhuohao; Guo, Jing L; McBride, Jennifer D et al. (2018) Amyloid-? plaques enhance Alzheimer's brain tau-seeded pathologies by facilitating neuritic plaque tau aggregation. Nat Med 24:29-38
Xie, Long; Das, Sandhitsu R; Wisse, Laura E M et al. (2018) Early Tau Burden Correlates with Higher Rate of Atrophy in Transentorhinal Cortex. J Alzheimers Dis 62:85-92
Gallagher, Michael D; Chen-Plotkin, Alice S (2018) The Post-GWAS Era: From Association to Function. Am J Hum Genet 102:717-730

Showing the most recent 10 out of 720 publications