Clinical research is defined by the National Institutes of Health (NIH) as research conducted with human subjects or using materials of human origin for which an investigator interacts with human subjects.[7] Consistent with the definition used by the NIH and the Institute of Medicine (IOM), we define the term """"""""Clinical Research Enterprise"""""""" as a wide spectrum of research and its applications?from the beginnings of human-oriented bench-top research and its application to patient care, to clinical epidemiology, health services research, outcomes research, and incorporation of these findings into health- and self-care in the community.[8] The major components of the Clinical Research Enterprise include private and public sponsors, research organizations, investigators, participants, oversight entities and stakeholders/consumers. The CLC goal is to create and disseminate evidence-based methods for promoting clinical research in minority communities, to increase community engagement in the clinical research enterprise. Our multi-level strategies will be to: work with communities and researchers to disseminate effective methods for promoting research opportunities, leverage institutional and community infrastructure to support community engagement (participation of community-based organizations, community physicians, patients, and research volunteers) in ail clinical research, and disseminate results of minority aging research to community partners, focusing on San Francisco Bay Area African American, Asian, and Latino populations. Achieving these objectives will result in increased opportunities for minority populations to engage in and benefit from research advances.

National Institute of Health (NIH)
National Institute on Aging (NIA)
Center Core Grants (P30)
Project #
Application #
Study Section
Special Emphasis Panel (ZAG1)
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of California San Francisco
San Francisco
United States
Zip Code
Napoles, A; Cook, E; Ginossar, T et al. (2017) Applying a Conceptual Framework to Maximize the Participation of Diverse Populations in Cancer Clinical Trials. Adv Cancer Res 133:77-94
Nápoles, Anna María; Ortiz, Carmen; Santoyo-Olsson, Jasmine et al. (2017) Post-Treatment Survivorship Care Needs of Spanish-speaking Latinas with Breast Cancer. J Community Support Oncol 15:20-27
Mayeda, Elizabeth R; Glymour, M Maria; Quesenberry, Charles P et al. (2017) Survival after dementia diagnosis in five racial/ethnic groups. Alzheimers Dement 13:761-769
Hurstak, Emily; Johnson, Julene K; Tieu, Lina et al. (2017) Factors associated with cognitive impairment in a cohort of older homeless adults: Results from the HOPE HOME study. Drug Alcohol Depend 178:562-570
Harawa, Nina T; Manson, Spero M; Mangione, Carol M et al. (2017) Strategies for enhancing research in aging health disparities by mentoring diverse investigators. J Clin Transl Sci 1:167-175
Huang, Susan; Duong, Thomas; Ieong, Liss et al. (2017) Understanding Falls Risk and Impacts in Chinese American Older Patients at a Community Health Center. J Community Health 42:763-769
Mayeda, Elizabeth R; Glymour, M Maria; Quesenberry Jr, Charles P et al. (2017) Heterogeneity in 14-year Dementia Incidence Between Asian American Subgroups. Alzheimer Dis Assoc Disord 31:181-186
Ramirez, Julio; Elmofty, May; Castillo, Esperanza et al. (2017) Evaluation of cortisol and telomere length measurements in ethnically diverse women with breast cancer using culturally sensitive methods. J Community Genet 8:75-86
Nápoles, Anna María; Santoyo-Olsson, Jasmine; Stewart, Anita L et al. (2017) Evaluating the Implementation of a Translational Peer-Delivered Stress Management Program for Spanish-Speaking Latina Breast Cancer Survivors. J Cancer Educ :
Johnson, Julene K; Louhivuori, Jukka; Siljander, Eero (2017) Comparison of Well-being of Older Adult Choir Singers and the General Population in Finland: A Case-Control Study. Music Sci 21:178-194

Showing the most recent 10 out of 205 publications