Clinical research is defined by the National Institutes of Health (NIH) as research conducted with human subjects or using materials of human origin for which an investigator interacts with human subjects.[7] Consistent with the definition used by the NIH and the Institute of Medicine (IOM), we define the term """"""""Clinical Research Enterprise"""""""" as a wide spectrum of research and its applications?from the beginnings of human-oriented bench-top research and its application to patient care, to clinical epidemiology, health services research, outcomes research, and incorporation of these findings into health- and self-care in the community.[8] The major components of the Clinical Research Enterprise include private and public sponsors, research organizations, investigators, participants, oversight entities and stakeholders/consumers. The CLC goal is to create and disseminate evidence-based methods for promoting clinical research in minority communities, to increase community engagement in the clinical research enterprise. Our multi-level strategies will be to: work with communities and researchers to disseminate effective methods for promoting research opportunities, leverage institutional and community infrastructure to support community engagement (participation of community-based organizations, community physicians, patients, and research volunteers) in ail clinical research, and disseminate results of minority aging research to community partners, focusing on San Francisco Bay Area African American, Asian, and Latino populations. Achieving these objectives will result in increased opportunities for minority populations to engage in and benefit from research advances.

National Institute of Health (NIH)
National Institute on Aging (NIA)
Center Core Grants (P30)
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Special Emphasis Panel (ZAG1)
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University of California San Francisco
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Lee, Jonathan S; Nápoles, Anna; Mutha, Sunita et al. (2018) Hospital discharge preparedness for patients with limited English proficiency: A mixed methods study of bedside interpreter-phones. Patient Educ Couns 101:25-32
Jih, Jane; Stijacic-Cenzer, Irena; Seligman, Hilary K et al. (2018) Chronic disease burden predicts food insecurity among older adults. Public Health Nutr 21:1737-1742
Flatt, Jason D; Gilsanz, Paola; Quesenberry Jr, Charles P et al. (2018) Post-traumatic stress disorder and risk of dementia among members of a health care delivery system. Alzheimers Dement 14:28-34
Jih, Jane; Nguyen, Minh P; Ly, Irene et al. (2018) The Role of Physician Recommendation in Colorectal Cancer Screening Receipt Among Immigrant Chinese Americans. J Immigr Minor Health 20:1483-1489
Nápoles, Anna María; Stewart, Anita L (2018) Transcreation: an implementation science framework for community-engaged behavioral interventions to reduce health disparities. BMC Health Serv Res 18:710
Vijayaraghavan, Maya; Olsen, Pamela; Weeks, John et al. (2018) Older African American Homeless-Experienced Smokers' Attitudes Toward Tobacco Control Policies-Results from the HOPE HOME Study. Am J Health Promot 32:381-391
Pratap, Abhishek; Renn, Brenna N; Volponi, Joshua et al. (2018) Using Mobile Apps to Assess and Treat Depression in Hispanic and Latino Populations: Fully Remote Randomized Clinical Trial. J Med Internet Res 20:e10130
Garcia, Andrea N; Kuo, Tony; Arangua, Lisa et al. (2018) Factors Associated With Medical School Graduates' Intention to Work With Underserved Populations: Policy Implications for Advancing Workforce Diversity. Acad Med 93:82-89
Nápoles, Anna María; Santoyo-Olsson, Jasmine; Stewart, Anita L et al. (2018) Evaluating the Implementation of a Translational Peer-Delivered Stress Management Program for Spanish-Speaking Latina Breast Cancer Survivors. J Cancer Educ 33:875-884
Portacolone, Elena; Johnson, Julene K; Covinsky, Kenneth E et al. (2018) The Effects and Meanings of Receiving a Diagnosis of Mild Cognitive Impairment or Alzheimer's Disease When One Lives Alone. J Alzheimers Dis 61:1517-1529

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