The overall goal of the Yale Research Career Development Core (RCDC) is to identify and train a cadre ofjunior investigators who will be future leaders in aging research, with the skills necessary to design/conductbiological, translational, and clinical studies of multifactorial geriatric health conditions.
The specific aims are: (1) to promote the career development and acquisition of research skills of selected junior facultythrough the provision of salary, infrastructure/technical, and other career development support; (2) to provideand facilitate priority access by junior faculty to the resource cores' expertise and services for the design,conduct, and analysis of studies addressing multifactorial geriatric health conditions; (3) to promote thedevelopment of skills for translational research (basic clinical basic; clinical > practice) that addressesour focus on multifactorial geriatric health conditions; (4) to identify and foster opportunities forinterdisciplinary research; (5) to sponsor a yearly junior faculty retreat that provides intensive training andsupport in research career development; (6) to provide and facilitate access to educational activities in agingresearch locally and nationally; and (7) to enhance access to other career development resources, such asprotocol development, information on funding sources, grant resource library, suitable mentors andcollaborators, appropriate study populations, and geriatric instrument catalog. As reflected in these aims,there will be a greater emphasis during the next funding cycle on translational and interdisciplinary research.Dr. Thomas Gill, an NIH-funded clinical investigator with international stature for his work on functionaldecline and disability and with proven leadership and mentorship abilities, will lead the RCDC. For the firstyear, 4 candidates of outstanding promise, representing different disciplines with diverse backgrounds andinterests, have been selected: Sarwat Chaudhry, MD (General Medicine), Manisha Juthani-Mehta, MD(Infectious Disease), Arthur Simen, MD, PhD (Molecular Psychiatry and Human Genetics), and Ji Li, PhD(Cardiology). Successful renewal of the Older Americans Independence Center (OAIC) will allow us to buildon many of the successful procedures that we have established over the past 15 years and to continue toaddress the scarcity of clinical, translational and basic science investigators with optimal skills and training torigorously study the etiology, prognosis and management of multifactorial geriatric health conditions.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Center Core Grants (P30)
Project #
2P30AG021342-06
Application #
7424114
Study Section
Special Emphasis Panel (ZAG1-ZIJ-8 (J1))
Project Start
2008-08-15
Project End
2013-05-31
Budget Start
2008-08-15
Budget End
2009-05-31
Support Year
6
Fiscal Year
2008
Total Cost
$492,991
Indirect Cost
Name
Yale University
Department
Type
DUNS #
043207562
City
New Haven
State
CT
Country
United States
Zip Code
06520
Wanigatunga, Amal A; Manini, Todd M; Cook, Delilah R et al. (2018) Community-Based Activity and Sedentary Patterns Are Associated With Cognitive Performance in Mobility-Limited Older Adults. Front Aging Neurosci 10:341
Gill, Thomas M; Han, Ling; Gahbauer, Evelyne A et al. (2018) Prognostic Effect of Changes in Physical Function Over Prior Year on Subsequent Mortality and Long-Term Nursing Home Admission. J Am Geriatr Soc 66:1587-1591
Makris, Una E; Ferrante, Lauren E; Mody, Lona (2018) Leadership Lessons: Building and Nurturing a High-Performing Clinical Research Team. J Am Geriatr Soc 66:1258-1261
Snyder, Peter J; Bhasin, Shalender; Cunningham, Glenn R et al. (2018) Lessons From the Testosterone Trials. Endocr Rev 39:369-386
Kabiri, Mina; Brauer, Michelle; Shafrin, Jason et al. (2018) Long-Term Health and Economic Value of Improved Mobility among Older Adults in the United States. Value Health 21:792-798
Agogo, George O; Ramsey, Christine M; Gnjidic, Danijela et al. (2018) Longitudinal associations between different dementia diagnoses and medication use jointly accounting for dropout. Int Psychogeriatr 30:1477-1487
Stabenau, Hans F; Becher, Robert D; Gahbauer, Evelyne A et al. (2018) Functional Trajectories Before and After Major Surgery in Older Adults. Ann Surg 268:911-917
Rosso, Andrea L; Metti, Andrea L; Glynn, Nancy W et al. (2018) Dopamine-Related Genotypes and Physical Activity Change During an Intervention: The Lifestyle Interventions and Independence for Elders Study. J Am Geriatr Soc 66:1172-1179
Ferrante, Lauren E; Pisani, Margaret A; Murphy, Terrence E et al. (2018) The Association of Frailty With Post-ICU Disability, Nursing Home Admission, and Mortality: A Longitudinal Study. Chest 153:1378-1386
Liu, Zuyun; Han, Ling; Wang, Xiaofeng et al. (2018) Disability Prior to Death Among the Oldest-Old in China. J Gerontol A Biol Sci Med Sci 73:1701-1707

Showing the most recent 10 out of 691 publications