This application proposes the renewal of an NIA Edward R. Roybal Center at the University of Alabama at Birmingham. The theme of the current Center is "Translational Research on Aging and Mobility." With respect to the Thematic Areas of Focus for our renewal application, we propose to continue to investigate Mechanisms of Behavior Change related to decision-making, cognition, motivation, positive health behaviors, and well-being. We will also continue to develop and evaluate novel interventions exploiting the malleability or plasticity of biobehavioral risk mechanisms associated with adverse aging outcomes. We will also develop and evaluate novel methods for analyzing programs affecting older populations and novel programs or practices at homes, workplaces, or firms benefitting older people. These themes are illustrated in ongoing Center projects and proposed pilot projects. Our ultimate goal for the UAB Roybal Center is to benefit the lives of older people by improving physical, cognitive and visual function in order to enhance quality of life, increased productivity, and minimize the need for care. The Center continuation proposes two cores, each designed to enhance the research infrastructure necessary to accomplish the objectives of the Center, and to promote translational research in the many affiliated Center projects. The proposed Center will consist of a management core, which will provide data management and biostatistical services, technical support, access to a recruitment database, access to assessment tools for use in Center research, access to a driving simulator facility, and a driving assessment clinic. The Management Core will also facilitate collaborations among researchers and commercial interests, and insure that new findings of the Center are communicated to the scientific community, health care professionals, government policy makers, and the public. A pilot grant core will foster the development of new ideas and interventions of benefit to older adults. The overall goal is to systematically evaluate and translate research into products, procedures, and policies that impact the day-to-day functioning of older adults, extending this work to the prevention of functional decline (with middle-aged adults), both at home and in the workplace.

Public Health Relevance

The UAB Roybal Center provides the research infrastructure to facilitate the development of new products and technologies to enhance the day-to-day functioning of older adults through enhanced physical, cognitive, and sensory function which leads to enhanced mobility, health, and quality of life, the Center facilitates collaborations among academic researchers and commercial interests, developing innovative networks of scientists with interests in translational research.

National Institute of Health (NIH)
Center Core Grants (P30)
Project #
Application #
Study Section
Special Emphasis Panel (ZAG1)
Program Officer
Nielsen, Lisbeth
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of Alabama Birmingham
Schools of Arts and Sciences
United States
Zip Code
Kaur, Jaspreet; Dodson, Joan E; Steadman, Laura et al. (2014) Predictors of improvement following speed of processing training in middle-aged and older adults with HIV: a pilot study. J Neurosci Nurs 46:23-33
Hadley, Jennifer A; Nenert, Rodolphe; Kraguljac, Nina V et al. (2014) Ventral tegmental area/midbrain functional connectivity and response to antipsychotic medication in schizophrenia. Neuropsychopharmacology 39:1020-30
Owsley, Cynthia; McGwin Jr, Gerald; Elgin, Jennifer et al. (2014) Visually impaired drivers who use bioptic telescopes: self-assessed driving skills and agreement with on-road driving evaluation. Invest Ophthalmol Vis Sci 55:330-6
Vance, David E; Fazeli, Pariya L; Ball, David A et al. (2014) Cognitive functioning and driving simulator performance in middle-aged and older adults with HIV. J Assoc Nurses AIDS Care 25:e11-26
Sandlin, Daniel; McGwin Jr, Gerald; Owsley, Cynthia (2014) Association between vision impairment and driving exposure in older adults aged 70 years and over: a population-based examination. Acta Ophthalmol 92:e207-12
Fazeli, Pariya L; Crowe, Michael; Ross, Lesley A et al. (2014) Cognitive Functioning in Adults Aging with HIV: A Cross-Sectional Analysis of Cognitive Subtypes and Influential Factors. J Clin Res HIV AIDS Prev 1:155-169
Huisingh, Carrie; McGwin Jr, Gerald; Orman, Katherine A et al. (2014) Frequent falling and motor vehicle collision involvement of older drivers. J Am Geriatr Soc 62:123-9
Pearce, Patricia F; Christian, Becky J; Smith, Sandra L et al. (2014) Research methods for graduate students: a practical framework to guide teachers and learners. J Am Assoc Nurse Pract 26:19-31
Kennedy, Richard E; Williams, Courtney P; Sawyer, Patricia et al. (2014) Comparison of in-person and telephone administration of the Mini-Mental State Examination in the University of Alabama at Birmingham Study of Aging. J Am Geriatr Soc 62:1928-32
Vance, David E; McDougall Jr, Graham J; Wilson, Natalie et al. (2014) Cognitive Consequences of Aging with HIV: Implications for Neuroplasticity and Rehabilitation. Top Geriatr Rehabil 30:35-45

Showing the most recent 10 out of 63 publications