Foster optimal balance and mobility and reduce injurious falls among older Americans. Our goals for this five year renewal award are to i. Promote multidisciplinary basic, translational and clinical inquiry into the causes, consequences and treatment of age related changes in balance and mobility, 2. Train young investigators from multiple disciplines within a vibrant intellectual and collaborative environment and 3) Serve as a resource and part:ner to other OAICs, investigators, institutions and the public. Our theme has evolved from a focus on balance and aging to one that better incorporates contemporary perspectives about the interface between balance and mobility, especially the role of control of motion during weight bearing activity. The OAIC has three Resource Cores (RCi- Clinical and Population Research Core, RC2- Tech Core and RC3- Data Management and Analysis Core) an RCDC, a PESC and an LAC. We propose four pilot studies and three developmental projects that reflect the scope and collaborative spirit of our program. The program integrates over 50 externally funded projects, funds three Pepper Scholars and provides support and training to over 20 additional young investigators who are funded through other sources of institutional and individual career awards.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Center Core Grants (P30)
Project #
5P30AG024827-07
Application #
7940850
Study Section
Special Emphasis Panel (ZAG1-ZIJ-8 (A1))
Program Officer
Eldadah, Basil A
Project Start
2004-09-30
Project End
2014-08-31
Budget Start
2010-09-01
Budget End
2011-08-31
Support Year
7
Fiscal Year
2010
Total Cost
$1,074,150
Indirect Cost
Name
University of Pittsburgh
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
004514360
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213
Armstrong, Nicole M; Carlson, Michelle C; Schrack, Jennifer et al. (2018) Late-Life Depressive Symptoms as Partial Mediators in the Associations between Subclinical Cardiovascular Disease with Onset of Mild Cognitive Impairment and Dementia. Am J Geriatr Psychiatry 26:559-568
Gregg, Edward W; Lin, Ji; Bardenheier, Barbara et al. (2018) Impact of Intensive Lifestyle Intervention on Disability-Free Life Expectancy: The Look AHEAD Study. Diabetes Care 41:1040-1048
Yashin, Anatoliy I; Fang, Fang; Kovtun, Mikhail et al. (2018) Hidden heterogeneity in Alzheimer's disease: Insights from genetic association studies and other analyses. Exp Gerontol 107:148-160
Sanders, Jason L; Guo, Wensheng; O'Meara, Ellen S et al. (2018) Trajectories of IGF-I Predict Mortality in Older Adults: The Cardiovascular Health Study. J Gerontol A Biol Sci Med Sci 73:953-959
Henderson, Rebecca M; Miller, Michael E; Fielding, Roger A et al. (2018) Maintenance of Physical Function 1 Year After Exercise Intervention in At-Risk Older Adults: Follow-up From the LIFE Study. J Gerontol A Biol Sci Med Sci 73:688-694
Baker, Joshua F; Newman, Anne B; Kanaya, Alka et al. (2018) The Adiponectin Paradox in the Elderly: Associations with Body Composition, Physical Functioning, and Mortality. J Gerontol A Biol Sci Med Sci :
Gray, Shelly L; Marcum, Zachary A; Schmader, Kenneth E et al. (2018) Update on Medication Use Quality and Safety in Older Adults, 2017. J Am Geriatr Soc 66:2254-2258
Bhasin, Shalender; Gill, Thomas M; Reuben, David B et al. (2018) Strategies to Reduce Injuries and Develop Confidence in Elders (STRIDE): A Cluster-Randomized Pragmatic Trial of a Multifactorial Fall Injury Prevention Strategy: Design and Methods. J Gerontol A Biol Sci Med Sci 73:1053-1061
Callahan, Kathryn E; Lovato, Laura; Miller, Michael E et al. (2018) Self-Reported Physical Function As a Predictor of Hospitalization in the Lifestyle Interventions and Independence for Elders Study. J Am Geriatr Soc 66:1927-1933
Thorpe, Carolyn T; Thorpe, Joshua M; Jiang, Tao et al. (2018) Healthcare utilization and expenditures for United States Medicare beneficiaries with systemic vasculitis. Semin Arthritis Rheum 47:507-519

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