Abstract

The goal of the Pilot/Exploratory Studies Core is to promote innovative multidisciplinary research related to mobility, balance and aging. The P/ESC manages the process of promotion, application, review, award and monitoring for Pilot/Exploratory Studies and Developmental projects. Priorities for awards include relevance to the OAIC theme, potential for independent funding, new multidisciplinary collaboration and translational potential. Additional priorities for Development Projects are potential to advance research methods in the area of mobility, balance and aging, degree of innovation and potential for incorporation into OAIC future studies. In order to make the most efficient use of resources, projects that serve as add-ons to existing funded studies are encouraged. Proposed first year pilot studies include PES-i: Role of NF-kB in stem cells in aging, PES-2: Pre-operative treatment with electrical stimulation enhances aged muscle regenerative capacity and return to functional mobility post-operatively, PES-3 Investigation into the Mechanisms of Symptom Relief with Forward Flexion in Older Patients with Spinal Stenosis and PES-4:Variability, Stability and Smoothness of Walking.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Center Core Grants (P30)
Project #
5P30AG024827-10
Application #
8525283
Study Section
Special Emphasis Panel (ZAG1-ZIJ-8)
Project Start
Project End
Budget Start
2013-09-01
Budget End
2014-08-31
Support Year
10
Fiscal Year
2013
Total Cost
$73,571
Indirect Cost
$25,008

  Institution

Name
University of Pittsburgh
Department
Type
DUNS #
004514360
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213

  Publications

Rejeski, W Jack; Walkup, Michael P; Fielding, Roger A et al. (2018) Evaluating Accelerometry Thresholds for Detecting Changes in Levels of Moderate Physical Activity and Resulting Major Mobility Disability. J Gerontol A Biol Sci Med Sci 73:660-667
Forman, Daniel E; Zieman, Susan J (2018) ""Doc, I Think My Meds Are Killing Me! Please Help…"": Transdisciplinary Forces Unite to Refocus Pharmacotherapy for Older Adults. J Am Geriatr Soc :
Lunney, June R; Albert, Steven M; Boudreau, Robert et al. (2018) Mobility Trajectories at the End of Life: Comparing Clinical Condition and Latent Class Approaches. J Am Geriatr Soc 66:503-508
Forman, Daniel E; Maurer, Mathew S; Boyd, Cynthia et al. (2018) Multimorbidity in Older Adults With Cardiovascular Disease. J Am Coll Cardiol 71:2149-2161
Gray, Shelly L; Hart, Laura A; Perera, Subashan et al. (2018) Meta-analysis of Interventions to Reduce Adverse Drug Reactions in Older Adults. J Am Geriatr Soc 66:282-288
Marcum, Zachary A; Forsberg, Christopher W; Moore, Kathryn P et al. (2018) Mortality Associated with Metformin Versus Sulfonylurea Initiation: A Cohort Study of Veterans with Diabetes and Chronic Kidney Disease. J Gen Intern Med 33:155-165
Kotlarczyk, Mary P; Perera, Subashan; Nace, David A et al. (2018) Identifying Sarcopenia in Female Long-Term Care Residents: A Comparison of Current Guidelines. J Am Geriatr Soc 66:316-320
Edmiston, Elizabeth; Dolansky, Mary A; Zullo, Melissa et al. (2018) Octogenarians' post-acute care use after cardiac valve surgery and recovery: clinical implications. Geriatr Nurs 39:371-375
Liu, Zuyun; Hsu, Fang-Chi; Trombetti, Andrea et al. (2018) Effect of 24-month physical activity on cognitive frailty and the role of inflammation: the LIFE randomized clinical trial. BMC Med 16:185
Smagula, Stephen F; Karim, Helmet T; Rangarajan, Anusha et al. (2018) Association of Hippocampal Substructure Resting-State Functional Connectivity with Memory Performance in Older Adults. Am J Geriatr Psychiatry 26:690-699

Showing the most recent 10 out of 1292 publications