The goal of the Pilot/Exploratory Studies Core is to promote innovative multidisciplinary research related to mobility, balance and aging. The P/ESC manages the process of promotion, application, review, award and monitoring for Pilot/Exploratory Studies and Developmental projects. Priorities for awards include relevance to the OAIC theme, potential for independent funding, new multidisciplinary collaboration and translational potential. Additional priorities for Development Projects are potential to advance research methods in the area of mobility, balance and aging, degree of innovation and potential for incorporation into OAIC future studies. In order to make the most efficient use of resources, projects that serve as add-ons to existing funded studies are encouraged. Proposed first year pilot studies include PES-i: Role of NF-kB in stem cells in aging, PES-2: Pre-operative treatment with electrical stimulation enhances aged muscle regenerative capacity and return to functional mobility post-operatively, PES-3 Investigation into the Mechanisms of Symptom Relief with Forward Flexion in Older Patients with Spinal Stenosis and PES-4:Variability, Stability and Smoothness of Walking.

National Institute of Health (NIH)
National Institute on Aging (NIA)
Center Core Grants (P30)
Project #
Application #
Study Section
Special Emphasis Panel (ZAG1-ZIJ-8)
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of Pittsburgh
United States
Zip Code
Lange-Maia, Brittney S; Newman, Anne B; Strotmeyer, Elsa S et al. (2015) Performance on fast- and usual-paced 400-m walk tests in older adults: are they comparable? Aging Clin Exp Res 27:309-14
Albert, Steven M; Bear-Lehman, Jane; Anderson, Stewart J (2015) Declines in mobility and changes in performance in the instrumental activities of daily living among mildly disabled community-dwelling older adults. J Gerontol A Biol Sci Med Sci 70:71-7
Hawkins, Marquis; Newman, Anne B; Madero, Magdalena et al. (2015) TV Watching, but Not Physical Activity, Is Associated With Change in Kidney Function in Older Adults. J Phys Act Health 12:561-8
Aspinall, Sherrie L; Zhao, Xinhua; Semla, Todd P et al. (2015) Epidemiology of drug-disease interactions in older veteran nursing home residents. J Am Geriatr Soc 63:77-84
Albert, Steven M; Edelstein, Offer; King, Jennifer et al. (2015) Assessing the quality of a non-randomized pragmatic trial for primary prevention of falls among older adults. Prev Sci 16:31-40
Farrokhi, Shawn; O'Connell, Megan; Fitzgerald, G Kelley (2015) Altered gait biomechanics and increased knee-specific impairments in patients with coexisting tibiofemoral and patellofemoral osteoarthritis. Gait Posture 41:81-5
Santanasto, Adam J; Glynn, Nancy W; Jubrias, Sharon A et al. (2015) Skeletal Muscle Mitochondrial Function and Fatigability in Older Adults. J Gerontol A Biol Sci Med Sci 70:1379-85
Ward, Rachel E; Boudreau, Robert M; Caserotti, Paolo et al. (2015) Sensory and motor peripheral nerve function and longitudinal changes in quadriceps strength. J Gerontol A Biol Sci Med Sci 70:464-70
An, Ping; Miljkovic, Iva; Thyagarajan, Bharat et al. (2014) Genome-wide association study identifies common loci influencing circulating glycated hemoglobin (HbA1c) levels in non-diabetic subjects: the Long Life Family Study (LLFS). Metabolism 63:461-8
Chambers, A J; Parise, E; McCrory, J L et al. (2014) A comparison of prediction equations for the estimation of body fat percentage in non-obese and obese older Caucasian adults in the United States. J Nutr Health Aging 18:586-90

Showing the most recent 10 out of 425 publications