Abstract

The goal of the Pilot/Exploratory Studies Core (PESC) of the Pittsburgh OAIC is to promote and fund innovative multidisciplinary pilot research in the topic areas of mobility, balance and aging and their interfaces.
The Specific Aims of the PESC are to: 1. Promote innovative multidisciplinary research on mobility, balance and aging, 2. Encourage supplements to ongoing studies, 3. Promote innovative techniques and methods for research on mobility, balance and aging, 4. Partner with other UPITT groups [i.e., Clinical and Translational Science Institute (CTSI) and Aging Institute] that also offer pilot study awards to increase overall funding for individual pilot projects, 5. Promote, evaluate, and select for funding Standard pilot projects ($25,000-$50,000 per year), Small pilots (up to $10,000), and Developmental projects ($35,000-$70,000 per year), 6. Conduct post-award processes (e.g.,monitor adherence to ethics, safety, privacy, tracking of subsequent productivity and other related matters) for Standard, Small RCDC pilot projects, and Developmental projects. In year one of the renewal, we propose to fund four pilot research projects demonstrating the Pittsburgh OAIC's growth areas (interaction between multiple body tissues, community and health system update of interventions).

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Center Core Grants (P30)
Project #
5P30AG024827-15
Application #
9734990
Study Section
Special Emphasis Panel (ZAG1)
Project Start
Project End
Budget Start
2019-07-01
Budget End
2020-06-30
Support Year
15
Fiscal Year
2019
Total Cost
Indirect Cost

  Institution

Name
University of Pittsburgh
Department
Type
DUNS #
004514360
City
Pittsburgh
State
PA
Country
United States
Zip Code
15260

  Publications

Justice, Jamie N; Ferrucci, Luigi; Newman, Anne B et al. (2018) A framework for selection of blood-based biomarkers for geroscience-guided clinical trials: report from the TAME Biomarkers Workgroup. Geroscience 40:419-436
Agimi, Yll; Albert, Steven M; Youk, Ada O et al. (2018) Dementia and motor vehicle crash hospitalizations: Role of physician reporting laws. Neurology 90:e808-e813
Miller, Michael E; Magaziner, Jay; Marsh, Anthony P et al. (2018) Gait Speed and Mobility Disability: Revisiting Meaningful Levels in Diverse Clinical Populations. J Am Geriatr Soc 66:954-961
Gellad, Walid F; Thorpe, Joshua M; Zhao, Xinhua et al. (2018) Impact of Dual Use of Department of Veterans Affairs and Medicare Part D Drug Benefits on Potentially Unsafe Opioid Use. Am J Public Health 108:248-255
Trombetti, Andrea; Hars, Mélany; Hsu, Fang-Chi et al. (2018) Effect of Physical Activity on Frailty: Secondary Analysis of a Randomized Controlled Trial. Ann Intern Med 168:309-316
Jacob, Mini E; Marron, Megan M; Boudreau, Robert M et al. (2018) Age, Race, and Gender Factors in Incident Disability. J Gerontol A Biol Sci Med Sci 73:194-197
Zhao, Yujing; Tudorascu, Dana L; Lopez, Oscar L et al. (2018) Amyloid ? Deposition and Suspected Non-Alzheimer Pathophysiology and Cognitive Decline Patterns for 12 Years in Oldest Old Participants Without Dementia. JAMA Neurol 75:88-96
Hengeveld, Linda M; Wijnhoven, Hanneke A H; Olthof, Margreet R et al. (2018) Prospective associations of poor diet quality with long-term incidence of protein-energy malnutrition in community-dwelling older adults: the Health, Aging, and Body Composition (Health ABC) Study. Am J Clin Nutr 107:155-164
Lunney, June R; Albert, Steven M; Boudreau, Robert et al. (2018) Three Year Functional Trajectories Among Old Age Survivors and Decedents: Dying Eliminates a Racial Disparity. J Gen Intern Med 33:177-181
Buford, Thomas W; Manini, Todd M; Kairalla, John A et al. (2018) Mitochondrial DNA Sequence Variants Associated With Blood Pressure Among 2 Cohorts of Older Adults. J Am Heart Assoc 7:e010009

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