The Biostatistics and Data Management Core (RC3) is one of four resource cores in the OAIC at the University of Florida. The mission ofthe UF OAIC is (1) to assess the risk factors and better understand the biological mechanisms of physical disability in older adults, (2) to develop and test effective prevention therapies, and (3) to educate and train new investigators in research on aging and disability, while developing their leadership qualities. The Biostatistics and Data Management Core is a key cog in the interaction between scientists from many disciplines to accomplish this mission. The core functions as both a data analysis resource and as a data coordinating center, involved in constructing data collection forms and managing the data (including quality control) for the studies conducted within the OAIC. In this capacity, the core maintains and updates the registry for the Recruitment, Adherence, and Retention Core (RC4) and tracks all research conducted within the OAIC with a web tracking system. The core is involved in all phases of these studies including initial study design and sample size calculations pre-proposal, randomization, and state-of-the-art statistical analyses once the data are completed. For study designs and data for which currently methodology is lacking, the core has the expertise to develop new state of the art methodology to perform correct and appropriate analyses of data collected in the Center. The Biostatistics and Data Management Core also is involved in preparation of manuscripts for dissemination within the research community. Finally, the Core serves as a key resource to the Junior Scholars of the Research Career Development Core (RCDC), providing consulting services and periodic special interest training topics, such as research methods, power analysis, analysis of incomplete data, principles of data management, and analysis of longitudinal data.
The core ensures proper and efficient designs and analyses for all studies conducted to examine sarcopenia and aging. In addition, the core provides the interface to the UF&Shands research data repository which can be invaluable for recruiting, generating research hypotheses, and pilot studies. The core also provides essential training for junior investigators and Pepper Scholars on research design and statistical methods and analyses.
|Brakenridge, Scott C; Efron, Philip A; Stortz, Julie A et al. (2018) The impact of age on the innate immune response and outcomes after severe sepsis/septic shock in trauma and surgical intensive care unit patients. J Trauma Acute Care Surg 85:247-255|
|Shenkman, Elizabeth; Hurt, Myra; Hogan, William et al. (2018) OneFlorida Clinical Research Consortium: Linking a Clinical and Translational Science Institute With a Community-Based Distributive Medical Education Model. Acad Med 93:451-455|
|Hernandez, Abbi R; Hernandez, Caesar M; Campos, Keila et al. (2018) A Ketogenic Diet Improves Cognition and Has Biochemical Effects in Prefrontal Cortex That Are Dissociable From Hippocampus. Front Aging Neurosci 10:391|
|Liu, Xinyue; Carney, Paul R; Bussing, Regina et al. (2018) Stimulants Do Not Increase the Risk of Seizure-Related Hospitalizations in Children with Epilepsy. J Child Adolesc Psychopharmacol 28:111-116|
|Dahodwala, Nabila; Shah, Krunal; He, Ying et al. (2018) Sex disparities in access to caregiving in Parkinson disease. Neurology 90:e48-e54|
|Buford, Thomas W; Manini, Todd M; Kairalla, John A et al. (2018) Mitochondrial DNA Sequence Variants Associated With Blood Pressure Among 2 Cohorts of Older Adults. J Am Heart Assoc 7:e010009|
|Rillamas-Sun, Eileen; LaMonte, Michael J; Evenson, Kelly R et al. (2018) The Influence of Physical Activity and Sedentary Behavior on Living to Age 85 Years Without Disease and Disability in Older Women. J Gerontol A Biol Sci Med Sci 73:1525-1531|
|Chen, Haiying; Rejeski, W Jack; Gill, Thomas M et al. (2018) A Comparison of Self-report Indices of Major Mobility Disability to Failure on the 400-m Walk Test: The LIFE Study. J Gerontol A Biol Sci Med Sci 73:513-518|
|Bihorac, Azra; Ozrazgat-Baslanti, Tezcan; Ebadi, Ashkan et al. (2018) MySurgeryRisk: Development and Validation of a Machine-learning Risk Algorithm for Major Complications and Death After Surgery. Ann Surg :|
|Ravyts, Scott G; Dzierzewski, Joseph M; Grah, Stephanie C et al. (2018) Sleep and Pain in Mid- to Late-Life: An Exploration of Day-to-Day Pain Inconsistency. Clin Gerontol 41:123-129|
Showing the most recent 10 out of 1197 publications