The goal of the Biostatistics, Informatics, and Translational Research Core (RC-1) is to establish and an environment that promotes excellence in the design and execution of OAIC studies where best statistical practices guide the analysis of data, to facilitate the search for mechanisms underlying successful interventions, and to promote the translation of promising interventions into the clinic and community.The Core will organize Research Working Groups (RWGs) that will assist with the design, execution, and oversight of all University of Maryland Older Americans Independence Center's (OAIC) research, and will provide an informatics backbone, GERI, that will support all aspects of the Center's work. We will make sure that best statistical practices guide the design and execution of OAIC research, the analysis of data, and the interpretation of the results of the analysis. We will educate faculty, RCDC scholars Qr. faculty) and staff in the principles of statistics and epidemiology. Our Research Working Groups, composed of the study PI, the Pi's mentor (if the PI is an RCDC Scholar), and one member from each Core, will use the automated reports produced by GERI as they oversee the progress of OAIC studies and monitor study progress. The reports will support the RWGs'efforts to assure that OAIC studies are completed in a timely fashion, and will help the RWGs identify studies that have potential for translation from laboratory bench, to center-based studies, and to community-based interventions. GERI will collect and track requests for OAIC services (Request for Services System), will assist with the recruiting of subjects (Registry), will track study progress (Tracking Database), collect information regarding adverse events (Adverse Event Database), and will facilitate laboratory quality control (Quality Control and Outlier Detection Systems). Our educational efforts will include our lecture series as well as the formal didactic education provided by our institution's MPH program, our K30 program, which offers an MS in Clinical Research, and our summer course Clinical and Translational Research at UMB.

Public Health Relevance

Scientific investigation requires the collaboration of scientists with expertise in several areas along with meticulous attention to study design, conduct and execution. The Biostatics, Informatics, and Translational Research Core will encourage collaboration, ensure excellence in design, conduct and execution of studies, and will promote translation of our studies from the laboratory to the community.

National Institute of Health (NIH)
National Institute on Aging (NIA)
Center Core Grants (P30)
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Special Emphasis Panel (ZAG1-ZIJ-8)
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University of Maryland Baltimore
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Kwon, Ivy; Bharmal, Nazleen; Choi, Sarah et al. (2016) Older Ethnic Minority Women's Perceptions of Stroke Prevention and Walking. Womens Health Issues 26:80-6
Loane, David J; Kumar, Alok (2016) Microglia in the TBI brain: The good, the bad, and the dysregulated. Exp Neurol 275 Pt 3:316-27
Woytowicz, Elizabeth J; Rietschel, Jeremy C; Goodman, Ronald N et al. (2016) Determining Levels of Upper Extremity Movement Impairment by Applying a Cluster Analysis to the Fugl-Meyer Assessment of the Upper Extremity in Chronic Stroke. Arch Phys Med Rehabil :
Ryan, Alice S; Ivey, Frederick M; Serra, Monica C et al. (2016) Sarcopenia and Physical Function in Middle-Aged and Older Stroke Survivors. Arch Phys Med Rehabil :
Anderson, Dennis E; Quinn, Emily; Parker, Emily et al. (2016) Associations of Computed Tomography-Based Trunk Muscle Size and Density With Balance and Falls in Older Adults. J Gerontol A Biol Sci Med Sci 71:811-6
Sanses, Tatiana V D; Schiltz, Nicholas K; Couri, Bruna M et al. (2016) Functional status in older women diagnosed with pelvic organ prolapse. Am J Obstet Gynecol 214:613.e1-7
Barton, Joseph E; Graci, Valentina; Hafer-Macko, Charlene et al. (2016) Dynamic Balanced Reach: A Temporal and Spectral Analysis Across Increasing Performance Demands. J Biomech Eng 138:
Resnick, Barbara; Beaupre, Lauren; McGilton, Katherine S et al. (2016) Rehabilitation Interventions for Older Individuals With Cognitive Impairment Post-Hip Fracture: A Systematic Review. J Am Med Dir Assoc 17:200-5
Sacco, Paul; Smith, Cristan A; Harrington, Donna et al. (2016) Feasibility and Utility of Experience Sampling to Assess Alcohol Consumption Among Older Adults. J Appl Gerontol 35:106-20
Baxter, B Timothy; Matsumura, Jon; Curci, John et al. (2016) Non-invasive Treatment of Abdominal Aortic Aneurysm Clinical Trial (N-TA(3)CT): Design of a Phase IIb, placebo-controlled, double-blind, randomized clinical trial of doxycycline for the reduction of growth of small abdominal aortic aneurysm. Contemp Clin Trials 48:91-8

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