Core B: Program Development The Duke Center on the Demography of Aging will promote a highly synergistic and interdisciplinary environment to foster important research breakthroughs particulariy in the areas of biological and biomedical demography of aging (aka the biodemography of aging) and in the development and application of innovative mathematical and statistical demographic tools and methods to data. As part of its Program Development Core, the Center will help establish two new faculty positions at Duke, one an assistant professor having a focus on biodemography and the other an assistant professor with expertise in mathematical and statistical demography. These will be tenure-track positions each funded for five years. This Core also supports the Center's Pilot Project program. Three examples of pilot project research are included in the Duke application, with one project focusing on eariy life determinants of later life health in China, and the other two projects researching biomarkers of aging and decision-making in Indonesia and Mexico. Other topics that are central to the Duke Center's research program and for which pilot research projects may be funded include: male-female differences in health and survival, the genetics of aging, new approaches to mortality and morbidity forecasting, mathematical and statistical methods for estimating age when age is not known, and mathematical and statistical analyses of tempo and other distortions of mortality and morbidity rates when health conditions are changing. The work performed in Core B will foster new young faculty and will advance research in the critically important areas of the biodemography of aging and in the mathematical and statistical demography of aging

Public Health Relevance

By developing new research areas, by supporting and enlarging the worid's community of demographic scientists, and by developing new mathematical and statistical methods for the analysis of data related to the biodemography of aging as well as data management services, the Duke Center for the Demography of Aging will advance understanding of the determinants of healthy aging and longevity. This understanding is critical to the development of policy and programs that promote healthy aging.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Center Core Grants (P30)
Project #
5P30AG034424-05
Application #
8493960
Study Section
Special Emphasis Panel (ZAG1-ZIJ-3)
Project Start
Project End
Budget Start
2013-07-01
Budget End
2014-06-30
Support Year
5
Fiscal Year
2013
Total Cost
$236,809
Indirect Cost
$85,337
Name
Duke University
Department
Type
DUNS #
044387793
City
Durham
State
NC
Country
United States
Zip Code
27705
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Sun, Shiquan; Hood, Michelle; Scott, Laura et al. (2017) Differential expression analysis for RNAseq using Poisson mixed models. Nucleic Acids Res 45:e106
Stallard, Eric; Kinosian, Bruce; Stern, Yaakov (2017) Personalized predictive modeling for patients with Alzheimer's disease using an extension of Sullivan's life table model. Alzheimers Res Ther 9:75
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Domingue, Benjamin W; Liu, Hexuan; Okbay, Aysu et al. (2017) Genetic Heterogeneity in Depressive Symptoms Following the Death of a Spouse: Polygenic Score Analysis of the U.S. Health and Retirement Study. Am J Psychiatry 174:963-970
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Richmond-Rakerd, Leah S; Belsky, Daniel W (2017) Swedish Register Analysis of Divorce and Alcohol Use Disorder Highlights Social Relationships as a Target for Preventive Psychiatry and Genetic Research. Am J Psychiatry 174:411-413
Akushevich, I; Yashkin, A P; Kravchenko, J et al. (2017) Theory of partitioning of disease prevalence and mortality in observational data. Theor Popul Biol 114:117-127

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