(Administrative/Enrichment) The Administrative/Program Enrichment Core is the administrative and outreach arm of the proposed UAB Nathan Shock Center focused on comparative energetics and aging. Under the direction of Drs. Steven Austad and David Allison, the Core will manage, coordinate, publicize, and integrate the diverse activities of the Center. Specifically, the Core will provide oversight, administrative support, and fiscal management for the Center. In that role, the Core will produce annual evaluations and reports of the Center's progress and in consultation with the Internal and External Advisory Committees make programmatic changes if warranted. The Core will also be the organizational unit responsible for promoting basic aging research at UAB and nationally. This will be accomplished via a monthly seminar series focused on current controversies and major advances in the field, journal clubs/work-in-progress sessions, an annual research symposium, the development of on-line and on-site education and training activities in subject areas relevant to the Center's research focus. The Administrative Core will also establish a communication network via a bi-weekly must- read e-bulletin, email, and the UAB NSC website keep Center users and potential users engaged and informed of Center activities, funding opportunities, as well as the availability of new techniques and methodologies developed by the research cores. The Administrative Core will also be the organizational unit responsible for providing researchers outside UAB with access to the services and programs available through the Shock Center. This Core will also be responsible for developing collaborative activities with the other Nathan Shock Centers. Given these roles and responsibilities, the specific aims of the UAB Shock Center of Excellence in Basic Aging Research can be summarized as: 1. To provide day-to-day administrative support and financial management for the Center; 2. To ensure the coordination and integration among cores; 3. To leverage institutional resources for the Center as well as promote the services and activities of each of the Research Cores; 4. To evaluate and enhance the impact of each of the Research Cores on the research community; 5. To provide conceptual leadership and innovative education, training, and outreach programs for the aging research community; 6. To coordinate meetings, reports, and implement recommendations of the Internal and External Advisory Committees.
| Xu, Ming; Pirtskhalava, Tamar; Farr, Joshua N et al. (2018) Senolytics improve physical function and increase lifespan in old age. Nat Med 24:1246-1256 |
| Chusyd, Daniella E; Brown, Janine L; Hambly, Catherine et al. (2018) Adiposity and Reproductive Cycling Status in Zoo African Elephants. Obesity (Silver Spring) 26:103-110 |
| Mao, Kai; Quipildor, Gabriela Farias; Tabrizian, Tahmineh et al. (2018) Late-life targeting of the IGF-1 receptor improves healthspan and lifespan in female mice. Nat Commun 9:2394 |
| Brown, Andrew W; Kaiser, Kathryn A; Allison, David B (2018) Issues with data and analyses: Errors, underlying themes, and potential solutions. Proc Natl Acad Sci U S A 115:2563-2570 |
| Fischer, Kathleen E; Riddle, Nicole C (2018) Sex Differences in Aging: Genomic Instability. J Gerontol A Biol Sci Med Sci 73:166-174 |
| Rangarajan, Sunad; Bone, Nathaniel B; Zmijewska, Anna A et al. (2018) Metformin reverses established lung fibrosis in a bleomycin model. Nat Med 24:1121-1127 |
| Gibbs, Victoria K; Schwartz, Tonia S; Johnson, Maria S et al. (2018) No Significant Effect of Maternal Perception of the Food Environment on Reproductive Success or Pup Outcomes in C57BL/6J Mice. Obesity (Silver Spring) 26:723-729 |
| Zhang, Jianhua; Culp, Matilda Lillian; Craver, Jason G et al. (2018) Mitochondrial function and autophagy: integrating proteotoxic, redox, and metabolic stress in Parkinson's disease. J Neurochem 144:691-709 |
| Gardinassi, Luiz G; Arévalo-Herrera, Myriam; Herrera, Sócrates et al. (2018) Integrative metabolomics and transcriptomics signatures of clinical tolerance to Plasmodium vivax reveal activation of innate cell immunity and T cell signaling. Redox Biol 17:158-170 |
| Austad, Steven N (2018) The Comparative Biology of Mitochondrial Function and the Rate of Aging. Integr Comp Biol 58:559-566 |
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