Abstract

The DAB CFAR Developmental Core has made a significant impact on HIV/AIDS research programs since the inception of the Center in 1988. The primary tool of the Developmental Core is the Developmental Grant Program which funds peer reviewed intramural HIV/AIDS related research grants targeted to junior faculty members and investigators new to the HIV/AIDS field. Since the inception of this program, a total of $2.069.115 were used to competitively fund 87 Developmental grants, selected from a total of 235 applications submitted to the UAB CFAR Developmental Grant Program. This investment has yielded $65.537.542 in extramural grant direct cost funding for a return on investment of $31 for every $1 of Developmental Grant Program money. This value has been maintained over the last funding period with $20 per every 1 of CFAR Developmental grant money. Embedded in the Developmental Grant Program is the core's mentoring program. Applicants are provided an experienced mentor from the CFAR Executive Board or CFAR Core Director in a related research area to the proposed project.
The Specific Aims of the Developmental core are:
Specific Aim 1. Specific Aim 2. To continue to administer the highly successful CFAR Developmental Grant Program. The Developmental Core will continue to fund 4 high quality proposals each year. A mentoring program will be provided to each of the awardees. The Core will also facilitate development of IRGs designed to bring new HIV/AIDS research to the CFAR. To provide faculty development resources to HIV/AIDS investigators. The Developmental Core will provide services to facilitate grant submission and review. The Core will also implement new educational opportunities to graduate students and fellows to become familiar with HIV/AIDS research. The Developmental Core will continue to play an integral part in the continued vitality of the HIV/AIDS research endeavor. During the next funding period, several innovative, new programs will be developed to support CFAR interdisciplinary research groups (IRG) and individual UAB CFAR investigators.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Center Core Grants (P30)
Project #
5P30AI027767-25
Application #
8495864
Study Section
Special Emphasis Panel (ZAI1-SV-A)
Project Start
Project End
Budget Start
2013-06-01
Budget End
2014-05-31
Support Year
25
Fiscal Year
2013
Total Cost
$2,913,655
Indirect Cost
$205,184

  Institution

Name
University of Alabama Birmingham
Department
Type
DUNS #
063690705
City
Birmingham
State
AL
Country
United States
Zip Code
35294

  Publications

Rice, Whitney S; Logie, Carmen H; Napoles, Tessa M et al. (2018) Perceptions of intersectional stigma among diverse women living with HIV in the United States. Soc Sci Med 208:9-17
Elion, Richard A; Althoff, Keri N; Zhang, Jinbing et al. (2018) Recent Abacavir Use Increases Risk of Type 1 and Type 2 Myocardial Infarctions Among Adults With HIV. J Acquir Immune Defic Syndr 78:62-72
Fredericksen, R J; Gibbons, L; Brown, S et al. (2018) Medication understanding among patients living with multiple chronic conditions: Implications for patient-reported measures of adherence. Res Social Adm Pharm 14:540-544
Stoll, Matthew L; Weiss, Pamela F; Weiss, Jennifer E et al. (2018) Age and fecal microbial strain-specific differences in patients with spondyloarthritis. Arthritis Res Ther 20:14
Subramaniam, Akila; Van Der Pol, William J; Ptacek, Travis et al. (2018) Midtrimester microbial DNA variations in maternal serum of women who experience spontaneous preterm birth. J Matern Fetal Neonatal Med :1-9
Kay, Emma S; Rice, Whitney S; Crockett, Kaylee B et al. (2018) Experienced HIV-Related Stigma in Health Care and Community Settings: Mediated Associations With Psychosocial and Health Outcomes. J Acquir Immune Defic Syndr 77:257-263
Xu, Wanli; Luo, Zhenwu; Alekseyenko, Alexander V et al. (2018) Distinct systemic microbiome and microbial translocation are associated with plasma level of anti-CD4 autoantibody in HIV infection. Sci Rep 8:12863
Smith, Samuel R; Schaaf, Kaitlyn; Rajabalee, Nusrah et al. (2018) The phosphatase PPM1A controls monocyte-to-macrophage differentiation. Sci Rep 8:902
Wang, Yong; Schafer, Cara C; Hough, Kenneth P et al. (2018) Myeloid-Derived Suppressor Cells Impair B Cell Responses in Lung Cancer through IL-7 and STAT5. J Immunol 201:278-295
Jones, Robert B; Dorsett, Kaitlyn A; Hjelmeland, Anita B et al. (2018) The ST6Gal-I sialyltransferase protects tumor cells against hypoxia by enhancing HIF-1? signaling. J Biol Chem 293:5659-5667

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