The DAB CFAR Developmental Core has made a significant impact on HIV/AIDS research programs since the inception of the Center in 1988. The primary tool of the Developmental Core is the Developmental Grant Program which funds peer reviewed intramural HIV/AIDS related research grants targeted to junior faculty members and investigators new to the HIV/AIDS field. Since the inception of this program, a total of $2.069.115 were used to competitively fund 87 Developmental grants, selected from a total of 235 applications submitted to the UAB CFAR Developmental Grant Program. This investment has yielded $65.537.542 in extramural grant direct cost funding for a return on investment of $31 for every $1 of Developmental Grant Program money. This value has been maintained over the last funding period with $20 per every 1 of CFAR Developmental grant money. Embedded in the Developmental Grant Program is the core's mentoring program. Applicants are provided an experienced mentor from the CFAR Executive Board or CFAR Core Director in a related research area to the proposed project.
The Specific Aims of the Developmental core are:
Specific Aim 1. Specific Aim 2. To continue to administer the highly successful CFAR Developmental Grant Program. The Developmental Core will continue to fund 4 high quality proposals each year. A mentoring program will be provided to each of the awardees. The Core will also facilitate development of IRGs designed to bring new HIV/AIDS research to the CFAR. To provide faculty development resources to HIV/AIDS investigators. The Developmental Core will provide services to facilitate grant submission and review. The Core will also implement new educational opportunities to graduate students and fellows to become familiar with HIV/AIDS research. The Developmental Core will continue to play an integral part in the continued vitality of the HIV/AIDS research endeavor. During the next funding period, several innovative, new programs will be developed to support CFAR interdisciplinary research groups (IRG) and individual UAB CFAR investigators.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Center Core Grants (P30)
Project #
5P30AI027767-25
Application #
8495864
Study Section
Special Emphasis Panel (ZAI1-SV-A)
Project Start
Project End
Budget Start
2013-06-01
Budget End
2014-05-31
Support Year
25
Fiscal Year
2013
Total Cost
$2,913,655
Indirect Cost
$205,184
Name
University of Alabama Birmingham
Department
Type
DUNS #
063690705
City
Birmingham
State
AL
Country
United States
Zip Code
35294
Bateman, Allen C; Chibwesha, Carla J; Parham, Groesbeck P (2015) Minimizing verification bias in cervical cancer screening of HIV-infected women. Int J Gynaecol Obstet 128:269-70
Miller, Michelle M; Akaronu, Nnenna; Thompson, Elizabeth M et al. (2015) Modulating DNA methylation in activated CD8+ T cells inhibits regulatory T cell-induced binding of Foxp3 to the CD8+ T Cell IL-2 promoter. J Immunol 194:990-8
Li, Jun; Hsu, Hui-Chen; Ding, Yana et al. (2014) Inhibition of fucosylation reshapes inflammatory macrophages and suppresses type II collagen-induced arthritis. Arthritis Rheumatol 66:2368-79
Mugavero, Michael J; Westfall, Andrew O; Cole, Stephen R et al. (2014) Beyond core indicators of retention in HIV care: missed clinic visits are independently associated with all-cause mortality. Clin Infect Dis 59:1471-9
Stevenson, Catherine; de la Rosa, Gonzalo; Anderson, Christopher S et al. (2014) Essential role of Elmo1 in Dock2-dependent lymphocyte migration. J Immunol 192:6062-70
Yuan, Furong; Yosef, Nejla; Lakshmana Reddy, Chetan et al. (2014) CCR2 gene deletion and pharmacologic blockade ameliorate a severe murine experimental autoimmune neuritis model of Guillain-Barré syndrome. PLoS One 9:e90463
Parker, Ivana Kennedy; Roberts, Ladeidra Monet; Hansen, Laura et al. (2014) Pro-atherogenic shear stress and HIV proteins synergistically upregulate cathepsin K in endothelial cells. Ann Biomed Eng 42:1185-94
Huijbregts, Richard P H; Michel, Katherine G; Hel, Zdenek (2014) Effect of progestins on immunity: medroxyprogesterone but not norethisterone or levonorgestrel suppresses the function of T cells and pDCs. Contraception 90:123-9
Sarzotti-Kelsoe, Marcella; Daniell, Xiaoju; Todd, Christopher A et al. (2014) Optimization and validation of a neutralizing antibody assay for HIV-1 in A3R5 cells. J Immunol Methods 409:147-60
Li, Hao; Hsu, Hui-Chen; Wu, Qi et al. (2014) IL-23 promotes TCR-mediated negative selection of thymocytes through the upregulation of IL-23 receptor and ROR?t. Nat Commun 5:4259

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