The purpose of the Baylor-UTHouston CFAR Developmental Core is to foster the development of HIV/AIDS-related research at Baylor and UTHouston through investigator-initiated pilot project awards and the support of interdisciplinary research projects. This Core has an impressive record of accomplishments. In the current funding period (2004-2008), $605,000 in Developmental pilot awards supported 17 projects on basic, clinical, and behavioral science research topics. These awards led to external funding totaling $11.8 million, representing nearly 20-fold leveraging of CFAR funds invested. For the longer period since the establishment of the CFAR (1995-2008), CFAR Developmental grants have resulted in external funding of $24.3 million that reflected 18.7-fold leveraging of invested funds. The Developmental Core also supports the development of Scientific Programs that draw on strengths, opportunities, and expertise at our CFAR. We have identified """"""""HIV-Associated Malignancies"""""""" as a new Scientific Program that involves collaboration with the Dan L. Duncan Cancer Center at Baylor. A mechanism of """"""""Collaborative Core Initiatives"""""""" is used to target specific interdisciplinary research opportunities at our CFAR. Allocations of Developmental funds among the various developmental programs each year will be determined by the CFAR Internal Advisory Committee. Awards for specific projects are made following a rigorous peer review system. The CFAR Developmental Core offers a comprehensive proactive mentoring program to assist in the career development of junior investigators involved in HIV/AIDS research;one-on-one mentoring is required for all junior faculty who apply for Developmental awards. The Core is led by Dr. Janet Butel, Director, and by Dr. Jagannadha Sastry, Associate Director, UT M.D. Anderson Cancer Center. Dr. Sastry is a new appointment with this submission.
The Center for AIDS Research (CFAR) at Baylor-UTHouston supports research on the pathogenesis, prevention, detection, and treatment of HIV infection and AIDS. The CFAR has been an essential catalyst for HIV/AIDS research in the Houston area. The State of Texas ranks fourth in the total number of AIDS cases in the United States. The Developmental Core fosters the development of HIV/AIDS-related research through the funding of pilot projects and also provides a mentoring program for junior investigators.
|Chaboub, Lesley S; Manalo, Jeanne M; Lee, Hyun Kyoung et al. (2016) Temporal Profiling of Astrocyte Precursors Reveals Parallel Roles for Asef during Development and after Injury. J Neurosci 36:11904-11917|
|Bui, Thanh Cong; Tran, Ly Thi-Hai; Hor, Leng Bun et al. (2016) Intravaginal Practices in Female Sex Workers in Cambodia: A Qualitative Study. Arch Sex Behav 45:935-43|
|Shore, Amy N; Chang, Chi-Hsuan; Kwon, Oh-Joon et al. (2016) PTEN is required to maintain luminal epithelial homeostasis and integrity in the adult mammary gland. Dev Biol 409:202-17|
|PethÅ‘, ZoltÃ¡n; Tanner, Mark R; Tajhya, Rajeev B et al. (2016) Different expression of Î² subunits of the KCa1.1 channel by invasive and non-invasive human fibroblast-like synoviocytes. Arthritis Res Ther 18:103|
|Kwon, Oh-Joon; Zhang, Li; Xin, Li (2016) Stem Cell Antigen-1 Identifies a Distinct Androgen-Independent Murine Prostatic Luminal Cell Lineage with Bipotent Potential. Stem Cells 34:191-202|
|Gundry, Michael C; Brunetti, Lorenzo; Lin, Angelique et al. (2016) Highly Efficient Genome Editing of Murine and Human Hematopoietic Progenitor Cells by CRISPR/Cas9. Cell Rep 17:1453-1461|
|Yang, Liubin; Rodriguez, Benjamin; Mayle, Allison et al. (2016) DNMT3A Loss Drives Enhancer Hypomethylation in FLT3-ITD-Associated Leukemias. Cancer Cell 29:922-34|
|Arya, Monisha; Patel, Sajani; Kumar, Disha et al. (2016) Why Physicians Don't Ask: Interpersonal and Intrapersonal Barriers to HIV Testing-Making a Case for a Patient-Initiated Campaign. J Int Assoc Provid AIDS Care 15:306-12|
|Toneff, M J; Sreekumar, A; Tinnirello, A et al. (2016) The Z-cad dual fluorescent sensor detects dynamic changes between the epithelial and mesenchymal cellular states. BMC Biol 14:47|
|Feng, Zizhen; Yao, Yuan; Zhou, Chao et al. (2016) Pharmacological inhibition of LSD1 for the treatment of MLL-rearranged leukemia. J Hematol Oncol 9:24|
Showing the most recent 10 out of 579 publications