The purpose of the Baylor-UTHouston CFAR Developmental Core is to foster the development of HIV/AIDS-related research at Baylor and UTHouston through investigator-initiated pilot project awards and the support of interdisciplinary research projects. This Core has an impressive record of accomplishments. In the current funding period (2004-2008), $605,000 in Developmental pilot awards supported 17 projects on basic, clinical, and behavioral science research topics. These awards led to external funding totaling $11.8 million, representing nearly 20-fold leveraging of CFAR funds invested. For the longer period since the establishment of the CFAR (1995-2008), CFAR Developmental grants have resulted in external funding of $24.3 million that reflected 18.7-fold leveraging of invested funds. The Developmental Core also supports the development of Scientific Programs that draw on strengths, opportunities, and expertise at our CFAR. We have identified

Public Health Relevance

The Center for AIDS Research (CFAR) at Baylor-UTHouston supports research on the pathogenesis, prevention, detection, and treatment of HIV infection and AIDS. The CFAR has been an essential catalyst for HIV/AIDS research in the Houston area. The State of Texas ranks fourth in the total number of AIDS cases in the United States. The Developmental Core fosters the development of HIV/AIDS-related research through the funding of pilot projects and also provides a mentoring program for junior investigators.

National Institute of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
Center Core Grants (P30)
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Special Emphasis Panel (ZAI1-JBS-A)
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Baylor College of Medicine
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Lam, Sharon; Sung, Julia; Cruz, Conrad et al. (2015) Broadly-specific cytotoxic T cells targeting multiple HIV antigens are expanded from HIV+ patients: implications for immunotherapy. Mol Ther 23:387-95
Gordon, Alasdair J E; Satory, Dominik; Wang, Mengyu et al. (2014) Removal of 8-oxo-GTP by MutT hydrolase is not a major contributor to transcriptional fidelity. Nucleic Acids Res 42:12015-26
Cerne, Jasmina Ziva; Hartig, Sean Michael; Hamilton, Mark Patrick et al. (2014) Protein kinase C inhibitors sensitize GNAQ mutant uveal melanoma cells to ionizing radiation. Invest Ophthalmol Vis Sci 55:2130-9
Blackmore, Julia K; Karmakar, Sudipan; Gu, Guowei et al. (2014) The SMRT coregulator enhances growth of estrogen receptor-?-positive breast cancer cells by promotion of cell cycle progression and inhibition of apoptosis. Endocrinology 155:3251-61
Singh, Ravi K; Xia, Zheng; Bland, Christopher S et al. (2014) Rbfox2-coordinated alternative splicing of Mef2d and Rock2 controls myoblast fusion during myogenesis. Mol Cell 55:592-603
Fongkaew, Warunee; Viseskul, Nongkran; Suksatit, Benjamas et al. (2014) Verifying quantitative stigma and medication adherence scales using qualitative methods among Thai youth living with HIV/AIDS. J Int Assoc Provid AIDS Care 13:69-77
Nguyen, Dan; Hsu, Jean W; Jahoor, Farook et al. (2014) Effect of increasing glutathione with cysteine and glycine supplementation on mitochondrial fuel oxidation, insulin sensitivity, and body composition in older HIV-infected patients. J Clin Endocrinol Metab 99:169-77
Chen, Jiyuan; Xia, Yunfeng; Lin, Xia et al. (2014) Smad3 signaling activates bone marrow-derived fibroblasts in renal fibrosis. Lab Invest 94:545-56
Ross, Michael W; Nyoni, Joyce; Ahaneku, Hycienth O et al. (2014) High HIV seroprevalence, rectal STIs and risky sexual behaviour in men who have sex with men in Dar es Salaam and Tanga, Tanzania. BMJ Open 4:e006175
Santiago, Felix W; Covaleda, Lina M; Sanchez-Aparicio, Maria T et al. (2014) Hijacking of RIG-I signaling proteins into virus-induced cytoplasmic structures correlates with the inhibition of type I interferon responses. J Virol 88:4572-85

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