Core H - The Protein Expression and Proteomics Core comprises two distinct, but highly interactive components at The Scripps Research Institute. Dr. John Elder, co-director, oversees the protein expression and purification component of the Core. Dr. Bruce Torbett, co-director, oversees the proteomics section, which provides state-of-the-art mass spectrometry, as well as other protein analytical methodology and instrumentation. The protein expression component facilitates the expression and purification of proteins required by the various CFAR-associated research programs. Moreover, the Core maintains in stock commonly used viral proteins, thus providing resources that may not otherwise be available to the community. The proteomic component of the Core provides state-of-the-art mass spectrometry instrumentation and bioinformatics, electrophoretic technologies, and additional bioanalytical instrumentation to analyze viral and cellular proteins important to ongoing studies by the members of the CFAR program. The Core also provides protein expression and proteomic advice, training, and consultation to the CFAR community. Access to such advice, reagents, methodologies, and technologies provides the CFAR community with unique resources not commonly found in research laboratories or cores.
The Protein Expression and Proteomics Core provides to CFAR-associated research programs services for the expression and purification of viral and cellular proteins as well as proteomic analyses of proteins from viruses and infected tissues and cells. The availability of advice, training, consultation, reagents, methodologies, and technologies offered by the Core is commonly beyond the reach of many research groups and, as such, is highly significant to the overall success ofthe CFAR research program.
|Mills, Jon C; Harman, Jeffrey S; Cook, Robert L et al. (2017) Comparative effectiveness of dual vs. single-action antidepressants on HIV clinical outcomes in HIV-infected people with depression. AIDS 31:2515-2524|
|Hoenigl, Martin; Braun, Dominique L; Kouyos, Roger et al. (2017) Evaluation of the Predictive Potential of the Short Acute Retroviral Syndrome Severity Score for HIV-1 Disease Progression in Individuals With Acute HIV Infection. J Acquir Immune Defic Syndr 74:e114-e117|
|Morris, Sheldon R; Zhao, Mitchell; Smith, Davey M et al. (2017) Longitudinal Viral Dynamics in Semen During Early HIV Infection. Clin Infect Dis 64:428-434|
|Wagner, Gabriel A; Landais, Elise; Caballero, Gemma et al. (2017) Intrasubtype B HIV-1 Superinfection Correlates with Delayed Neutralizing Antibody Response. J Virol 91:|
|Monroe, Anne K; Fleishman, John A; Voss, Cindy C et al. (2017) Assessing Antiretroviral Use During Gaps in HIV Primary Care Using Multisite Medicaid Claims and Clinical Data. J Acquir Immune Defic Syndr 76:82-89|
|Chaillon, Antoine; Nakazawa, Masato; Wertheim, Joel O et al. (2017) No Substantial Evidence for Sexual Transmission of Minority HIV Drug Resistance Mutations in Men Who Have Sex with Men. J Virol 91:|
|Hartzler, Bryan; Carlini, Beatriz H; Newville, Howard et al. (2017) Identifying HIV care enrollees at-risk for cannabis use disorder. AIDS Care 29:846-850|
|Akrami, Kevan; Coletta, Joelle; Mehta, Sanjay et al. (2017) Gordonia sternal wound infection treated with ceftaroline: case report and literature review. JMM Case Rep 4:e005113|
|Gianella, Sara; Taylor, Jeff; Brown, Timothy R et al. (2017) Can research at the end of life be a useful tool to advance HIV cure? AIDS 31:1-4|
|Spies, Georgina; Fennema-Notestine, Christine; Cherner, Mariana et al. (2017) Changes in cognitive function in women with HIV infection and early life stress. AIDS Care 29:14-23|
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