The primary goal of the Biostatistics and Biomedical Informatics Core (Core F) is to strengthen the statistical science and rigor of the HIV/AIDS-related research by providing state-of-the-art biostatistics and biomedical informatics support to Emory CFAR investigators. Core F will assure professional quality collaboration/consultation through the following four specific aims: (1) provide essential biostatistics, biomedical informatics and data management collaborative/consulting expertise to Emory CFAR investigators;(2) expand the services in a differentiated manner to meet the wide variety of needs of CFAR investigators, that will include fostering the development of new statistical and biomedical informatics methodology to meet the analytic challenges posed by the CFAR research community at Emory;(3) promote biostatistics and biomedical informatics education and training opportunities for CFAR investigators, and (4) engage in evaluation and strategic planning to improve the biostatistics and biomedical informatics support to CFAR investigators. Utilization of Core F resources should result in improved quality of HIV/AIDS-related research by making sure that the specific aims are written as testable research hypotheses with appropriate attention directed toward providing adequate statistical power for each of the primary and secondary research hypotheses. Operationally, Core F produces both synergy and efficiency in its interactions with both the translational and clinical CFAR investigators by basically providing them with seamless access to the faculty, staff and graduate students in Department of Biostatistics and Bioinformatics. Support from the School of Medicine and the School of Public Health allows CFAR investigators to take full advantage of the versatility of Core Fs superbly talented faculty and well trained graduate students. Core F is uniquely posed to support the development of a framework for an HIV clinical and biological database for the purpose of enhancing research and collaboration opportunities between clinical, translational and basic scientists interested in interdisciplinary HIV/AIDS research.
In conformance with the NIH National CFAR mission, the Biostatistics and Biomedical Informatics Core provides state-of-the-art essential support for Emory CFAR investigators. Through this Core effort, CFAR research studies are designed and conducted with strict attention to the detail necessary in order to allow for making sound inferences and decisions.
|Kannanganat, Sunil; Wyatt, Linda S; Gangadhara, Sailaja et al. (2016) High Doses of GM-CSF Inhibit Antibody Responses in Rectal Secretions and Diminish Modified Vaccinia Ankara/Simian Immunodeficiency Virus Vaccine Protection in TRIM5Î±-Restrictive Macaques. J Immunol 197:3586-3596|
|Kelley, Colleen F; Lai, Lilin; Ibegbu, Chris et al. (2016) Differences in expression of gut-homing receptors on CD4+ T cells in black and white HIV-negative men who have sex with men. AIDS 30:1305-8|
|Anderson, Albert M; Lennox, Jeffrey L; Nguyen, Minh L et al. (2016) Preliminary study of a novel cognitive assessment device for the evaluation of HIV-associated neurocognitive impairment. J Neurovirol 22:816-822|
|Kalokhe, Ameeta S; Ibegbu, Chris C; Kaur, Surinder P et al. (2016) INTIMATE PARTNER VIOLENCE IS ASSOCIATED WITH INCREASED CD4(+) T-CELL ACTIVATION AMONG HIV-NEGATIVE HIGH-RISK WOMEN. Pathog Immun 1:193-213|
|HernÃ¡ndez-Romieu, Alfonso C; del Rio, Carlos; HernÃ¡ndez-Ãvila, Juan Eugenio et al. (2016) CD4 Counts at Entry to HIV Care in Mexico for Patients under the ""Universal Antiretroviral Treatment Program for the Uninsured Population,"" 2007-2014. PLoS One 11:e0152444|
|White, Darcy; Grey, Jeremy A; Gorbach, Pamina M et al. (2016) Racial Differences in Partnership Attributes, Typologies, and Risk Behaviors Among Men Who Have Sex With Men in Atlanta, Georgia. Arch Sex Behav :|
|Sun, Xiaoyan; Peng, Limin; Huang, Yijian et al. (2016) Generalizing Quantile Regression for Counting Processes with Applications to Recurrent Events. J Am Stat Assoc 111:145-156|
|Ravindran, Rajesh; Loebbermann, Jens; Nakaya, Helder I et al. (2016) The amino acid sensor GCN2 controls gut inflammation by inhibiting inflammasome activation. Nature 531:523-7|
|Nasri, Hashem; Kabbani, Sarah; Bou Alwan, Melhim et al. (2016) Retrospective Study of Cryptococcal Meningitis With Elevated Minimum Inhibitory Concentration to Fluconazole in Immunocompromised Patients. Open Forum Infect Dis 3:ofw076|
|Haile, Woldeab B; Gavegnano, Christina; Tao, Sijia et al. (2016) The Janus kinase inhibitor ruxolitinib reduces HIV replication in human macrophages and ameliorates HIV encephalitis in a murine model. Neurobiol Dis 92:137-43|
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