The primary goal of the Biostatistics and Biomedical Informatics Core (Core F) is to strengthen the statistical science and rigor of the HIV/AIDS-related research by providing state-of-the-art biostatistics and biomedical informatics support to Emory CFAR investigators. Core F will assure professional quality collaboration/consultation through the following four specific aims: (1) provide essential biostatistics, biomedical informatics and data management collaborative/consulting expertise to Emory CFAR investigators;(2) expand the services in a differentiated manner to meet the wide variety of needs of CFAR investigators, that will include fostering the development of new statistical and biomedical informatics methodology to meet the analytic challenges posed by the CFAR research community at Emory;(3) promote biostatistics and biomedical informatics education and training opportunities for CFAR investigators, and (4) engage in evaluation and strategic planning to improve the biostatistics and biomedical informatics support to CFAR investigators. Utilization of Core F resources should result in improved quality of HIV/AIDS-related research by making sure that the specific aims are written as testable research hypotheses with appropriate attention directed toward providing adequate statistical power for each of the primary and secondary research hypotheses. Operationally, Core F produces both synergy and efficiency in its interactions with both the translational and clinical CFAR investigators by basically providing them with seamless access to the faculty, staff and graduate students in Department of Biostatistics and Bioinformatics. Support from the School of Medicine and the School of Public Health allows CFAR investigators to take full advantage of the versatility of Core Fs superbly talented faculty and well trained graduate students. Core F is uniquely posed to support the development of a framework for an HIV clinical and biological database for the purpose of enhancing research and collaboration opportunities between clinical, translational and basic scientists interested in interdisciplinary HIV/AIDS research.

Public Health Relevance

In conformance with the NIH National CFAR mission, the Biostatistics and Biomedical Informatics Core provides state-of-the-art essential support for Emory CFAR investigators. Through this Core effort, CFAR research studies are designed and conducted with strict attention to the detail necessary in order to allow for making sound inferences and decisions.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Center Core Grants (P30)
Project #
5P30AI050409-16
Application #
8704210
Study Section
Special Emphasis Panel (ZAI1)
Project Start
Project End
Budget Start
2014-08-01
Budget End
2015-07-31
Support Year
16
Fiscal Year
2014
Total Cost
Indirect Cost
Name
Emory University
Department
Type
DUNS #
City
Atlanta
State
GA
Country
United States
Zip Code
30322
Dillard, Rebecca S; Hampton, Cheri M; Strauss, Joshua D et al. (2018) Biological Applications at the Cutting Edge of Cryo-Electron Microscopy. Microsc Microanal 24:406-419
Haas, David W; Bradford, Yuki; Verma, Anurag et al. (2018) Brain neurotransmitter transporter/receptor genomics and efavirenz central nervous system adverse events. Pharmacogenet Genomics 28:179-187
Ke, Zunlong; Dillard, Rebecca S; Chirkova, Tatiana et al. (2018) The Morphology and Assembly of Respiratory Syncytial Virus Revealed by Cryo-Electron Tomography. Viruses 10:
Gianella, Sara; Marconi, Vincent C; Berzins, Baiba et al. (2018) Genital HIV-1 Shedding With Dolutegravir (DTG) Plus Lamivudine (3TC) Dual Therapy. J Acquir Immune Defic Syndr 79:e112-e114
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Nelson, Kristin N; Shah, N Sarita; Mathema, Barun et al. (2018) Spatial Patterns of Extensively Drug-Resistant Tuberculosis Transmission in KwaZulu-Natal, South Africa. J Infect Dis 218:1964-1973
Serota, David P; Rosenberg, Eli S; Lockard, Annie M et al. (2018) Beyond the Biomedical: Preexposure Prophylaxis Failures in a Cohort of Young Black Men Who Have Sex With Men in Atlanta, Georgia. Clin Infect Dis 67:965-970
Hightow-Weidman, Lisa B; Muessig, Kathryn; Rosenberg, Eli et al. (2018) University of North Carolina/Emory Center for Innovative Technology (iTech) for Addressing the HIV Epidemic Among Adolescents and Young Adults in the United States: Protocol and Rationale for Center Development. JMIR Res Protoc 7:e10365
Reyes-Robles, Tamara; Dillard, Rebecca S; Cairns, Lynne S et al. (2018) Vibrio cholerae outer membrane vesicles inhibit bacteriophage infection. J Bacteriol :

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