The Biostatistics Core (Core F) provides biostatistical collaboration, interdisciplinary connections, training and leadership for the HIV/AIDS-related research of the UNC CFAR. Core F provides a full spectrum of statistical consulting services as well as methodological innovations for complex statistical issues. The members of Core F proactively engage CFAR investigator to identify and deliver services essential for highly productive design, management, analysis and publication of AIDS research. Core F contributes to the framing of hypotheses, development of study designs, selection of best statistical strategies, and delivery of statistical analyses required for publications. Investigators new to AIDS research receive highest priority. Core F serves as a nexus linking statistical and biomedical scientists in HIV research;e.g., clinicians find statistical co-investigators while statisticians initiating AIDS-related methods research find clinical coinvestigators. Of mutual benefit, statistical professionals provide essential collaborative support while thriving on challenges presented by compelling datasets that demand new statistical methods. The organization of Core F, as a formal core, greatly enhances its efficiency and its abilities to connect communities of scientists, and to provide mentoring and training in AIDS research. Core F is widely recognized as a specialized facility conveniently located for CFAR scientists. Strong institutional support from the Biostatistics Department allows Core F to take full advantage of existing infrastructure, resources and contacts with faculty renowned for their expertise in specialized fields of statistical science. The Core's personnel proactively seek faculty and students interested in participating as new members of Core F. [Relevance to Public Health.] Consistent with the mission of the NIH CFAR Program, the Biostatistics Core of the UNC CFAR delivers essential biostatistical support and expertise to AIDS investigators, develops innovative solutions to statistical methodological challenges faced by these investigators, stimulates innovation and synergism by bringing to these investigators expanded arrays of best statistical resources, actively promotes expansion of the number of statistical professionals and graduate students involved in AIDS-related research, and provides mentoring and training to investigators new to HIV/AIDS research.

Public Health Relevance

Consistent with the mission of the NIH CFAR Program, the Biostatistics Core of the UNC CFAR delivers essential biostatistical support and expertise to AIDS investigators, develops innovative solutions to statistical methodological challenges faced by these investigators, stimulates innovation and synergism by bringing to these investigators expanded arrays of best statistical resources, actively promotes expansion of the number of statistical professionals and graduate students involved in AIDS-related research, and provides mentoring and training to investigators new to HIV/AIDS research.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Center Core Grants (P30)
Project #
5P30AI050410-13
Application #
8080832
Study Section
Special Emphasis Panel (ZAI1)
Project Start
Project End
Budget Start
2010-06-01
Budget End
2011-05-31
Support Year
13
Fiscal Year
2010
Total Cost
$277,129
Indirect Cost
Name
University of North Carolina Chapel Hill
Department
Type
DUNS #
608195277
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599
Evon, Donna M; Stewart, Paul W; Amador, Jipcy et al. (2018) A comprehensive assessment of patient reported symptom burden, medical comorbidities, and functional well being in patients initiating direct acting antiviral therapy for chronic hepatitis C: Results from a large US multi-center observational study. PLoS One 13:e0196908
Gausi, Blessings; Chagomerana, Maganizo B; Tang, Jennifer H et al. (2018) Human Immunodeficiency Virus Serodiscordance and Dual Contraceptive Method Use Among Human Immunodeficiency Virus-infected Men and Women in Lilongwe, Malawi. Sex Transm Dis 45:747-753
Kalayjian, Robert C; Albert, Jeffrey M; Cremers, Serge et al. (2018) Women have enhanced bone loss associated with phosphaturia and CD4+ cell restoration during initial antiretroviral therapy. AIDS 32:2517-2524
Altekruse, Sean F; Shiels, Meredith S; Modur, Sharada P et al. (2018) Cancer burden attributable to cigarette smoking among HIV-infected people in North America. AIDS 32:513-521
Cheng, Weibin; Xu, Huifang; Zhong, Fei et al. (2018) Can HIV service data be used for surveillance purposes?: a case study in Guangzhou, China. BMC Public Health 18:1268
Gradissimo, Ana; Lam, Jessica; Attonito, John D et al. (2018) Methylation of High-Risk Human Papillomavirus Genomes Are Associated with Cervical Precancer in HIV-Positive Women. Cancer Epidemiol Biomarkers Prev 27:1407-1415
AIDS-defining Cancer Project Working Group of IeDEA, COHERE in EuroCoord (2018) Non-Hodgkin lymphoma risk in adults living with HIV across five continents. AIDS 32:2777-2786
Price, Joan T; Mollan, Katie R; Fuseini, Nurain M et al. (2018) Vaginal progesterone to reduce preterm birth among HIV-infected pregnant women in Zambia: a feasibility study protocol. Pilot Feasibility Stud 4:21
Davy-Mendez, Thibaut; Napravnik, Sonia; Zakharova, Oksana et al. (2018) Acute HIV Infection and CD4/CD8 Ratio Normalization After Antiretroviral Therapy Initiation. J Acquir Immune Defic Syndr 79:510-518
Cole, Stephen R; Edwards, Jessie K; Westreich, Daniel et al. (2018) Estimating multiple time-fixed treatment effects using a semi-Bayes semiparametric marginal structural Cox proportional hazards regression model. Biom J 60:100-114

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