The Molecular Biology and Genomics Core of the HU CFAR will build upon the combined strengths of the pre-existing Virology/Molecular Biology core and the Genomics program (initiated in 2007). The primary goal of the new Genomics core is to enable CFAR investigators by providing access to and support with state-ofthe- art genomic technologies (including but not limited to viral sequencing, host genomics, gene expression profiling) for HIV/AIDS research projects. We will do this by offering guidance to those who wish to initiate genomics projects or incorporate genomic techniques into their research, and by referring investigators to key scientists with relevant expertise in the local genomics community, including those at the Broad Institute of Harvard and MIT. In addition, we will continue to provide services that have been offered previously at the Dana-Farber Cancer Institute Molecular Biology Core Facilities (through the pre-existing HU CFAR Virology/Molecular Biology core). Dr Paul de Bakker (currently HU CFAR Genomics Program Director) will be the new core director.
Genetics and genomics have become indispensable tools to develop a better understanding of HIV biology, specifically, how HIV interacts with the immune system, how it exhausts the immune system, and ultimately, how it leads to AIDS. We are allowing Harvard scientists to access these tools and maximize the impact of their research.
|Ramirez-Avila, Lynn; Regan, Susan; Chetty, Senica et al. (2015) HIV testing rates, prevalence, and knowledge among outpatients in Durban, South Africa: Time trends over four years. Int J STD AIDS 26:704-9|
|Psaros, Christina; Barinas, Jennifer; Robbins, Gregory K et al. (2015) Reflections on living with HIV over time: exploring the perspective of HIV-infected women over 50. Aging Ment Health 19:121-8|
|Drain, Paul K; Losina, Elena; Coleman, Sharon M et al. (2015) Value of urine lipoarabinomannan grade and second test for optimizing clinic-based screening for HIV-associated pulmonary tuberculosis. J Acquir Immune Defic Syndr 68:274-80|
|Chan, Brian T; Weiser, Sheri D; Boum, Yap et al. (2015) Persistent HIV-related stigma in rural Uganda during a period of increasing HIV incidence despite treatment expansion. AIDS 29:83-90|
|Rothchild, Alissa C; Jayaraman, Pushpa; Nunes-Alves, Cláudio et al. (2014) iNKT cell production of GM-CSF controls Mycobacterium tuberculosis. PLoS Pathog 10:e1003805|
|Blashill, Aaron J; Goshe, Brett M; Robbins, Gregory K et al. (2014) Body image disturbance and health behaviors among sexual minority men living with HIV. Health Psychol 33:677-80|
|Li, Hualin; Stephenson, Kathryn E; Kang, Zi Han et al. (2014) Common features of mucosal and peripheral antibody responses elicited by candidate HIV-1 vaccines in rhesus monkeys. J Virol 88:13510-5|
|Powis, Kathleen; Lockman, Shahin; Smeaton, Laura et al. (2014) Vitamin D insufficiency in HIV-infected pregnant women receiving antiretroviral therapy is not associated with morbidity, mortality or growth impairment in their uninfected infants in Botswana. Pediatr Infect Dis J 33:1141-7|
|Weinstein, Edward A; Ordonez, Alvaro A; DeMarco, Vincent P et al. (2014) Imaging Enterobacteriaceae infection in vivo with 18F-fluorodeoxysorbitol positron emission tomography. Sci Transl Med 6:259ra146|
|Sixsmith, Jaimie D; Panas, Michael W; Lee, Sunhee et al. (2014) Recombinant Mycobacterium bovis bacillus Calmette-Guérin vectors prime for strong cellular responses to simian immunodeficiency virus gag in rhesus macaques. Clin Vaccine Immunol 21:1385-95|
Showing the most recent 10 out of 350 publications