Abstract

The Harvard University (HU) CFAR Biostatistics Core is a distributed Core, with offices at three sites: the Dana Farber Cancer Institute (DFCI), the Massachusetts General Hospital (MGH), and the Harvard School of Public Health (HSPH);these three locations provide services to all the HU CFAR institutions. The Biostatistics Core provides statistical collaboration and consultation for HIV-related laboratory, animal, clinical, and outcome studies to CFAR members and their trainees and to investigators who are new to HIV research. Broadly, the services of the biostatistics core include: design (including sample size calculations and analysis plans for all studies and database management for clinical studies), analysis of data (including model results and graphs), and training (in statistical methods, computer packages, and graphical illustration).

Public Health Relevance

The Biostatistics Core improves the efficiency of studies and prevents fatal design flaws. Another function of the Biostatistics Core is to analyze data for investigators who are not trained to do more complicated analyses or to check whether the assumptions of an analysis method are violated.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Center Core Grants (P30)
Project #
5P30AI060354-10
Application #
8523745
Study Section
Special Emphasis Panel (ZAI1-SV-A)
Project Start
Project End
Budget Start
2013-08-01
Budget End
2014-07-31
Support Year
10
Fiscal Year
2013
Total Cost
$677,072
Indirect Cost
$50,598

  Institution

Name
Harvard University
Department
Type
DUNS #
082359691
City
Cambridge
State
MA
Country
United States
Zip Code
02138

  Publications

Thomas, Beena E; Subbaraman, Ramnath; Sellappan, Senthil et al. (2018) Pretreatment loss to follow-up of tuberculosis patients in Chennai, India: a cohort study with implications for health systems strengthening. BMC Infect Dis 18:142
O'Cleirigh, Conall; Pantalone, David W; Batchelder, Abigail W et al. (2018) Co-occurring psychosocial problems predict HIV status and increased health care costs and utilization among sexual minority men. J Behav Med 41:450-457
Mitton, Julian A; North, Crystal M; Muyanja, Daniel et al. (2018) Smoking cessation after engagement in HIV care in rural Uganda. AIDS Care 30:1622-1629
Cheng, Hao D; Grimm, Sebastian K; Gilman, Morgan Sa et al. (2018) Fine epitope signature of antibody neutralization breadth at the HIV-1 envelope CD4-binding site. JCI Insight 3:
Castillo-Mancilla, Jose R; Morrow, Mary; Boum, Yap et al. (2018) Brief Report: Higher ART Adherence Is Associated With Lower Systemic Inflammation in Treatment-Naive Ugandans Who Achieve Virologic Suppression. J Acquir Immune Defic Syndr 77:507-513
Mayer, Kenneth H (2018) Old Pathogen, New Challenges: A Narrative Review of the Multilevel Drivers of Syphilis Increasing in American Men Who Have Sex With Men. Sex Transm Dis 45:S38-S41
Kirtane, Ameya R; Abouzid, Omar; Minahan, Daniel et al. (2018) Development of an oral once-weekly drug delivery system for HIV antiretroviral therapy. Nat Commun 9:2
Mayer, Kenneth H; Chan, Philip A; R Patel, Rupa et al. (2018) Evolving Models and Ongoing Challenges for HIV Preexposure Prophylaxis Implementation in the United States. J Acquir Immune Defic Syndr 77:119-127
Calabrese, Sarah K; Earnshaw, Valerie A; Krakower, Douglas S et al. (2018) A Closer Look at Racism and Heterosexism in Medical Students' Clinical Decision-Making Related to HIV Pre-Exposure Prophylaxis (PrEP): Implications for PrEP Education. AIDS Behav 22:1122-1138
Richterman, Aaron; Cheung, Hoi Ching; Meiselbach, Mark K et al. (2018) Risk Factors for Self-Reported Cholera Within HIV-Affected Households in Rural Haiti. Open Forum Infect Dis 5:ofy127

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