The main goal of the Developmental Core (Core B) is to advance and promote HIV/AIDS research at the Chicago D-CFAR. The three institutions that comprise the D-CFAR have a diversity of strengths in basic, linical and social/behavioral science. However, there is a need to better integrate these research efforts across institutions as well as enhance our HIV/AIDS-related funding, especially at RUMC and Cook County. This can be accomplished by attracting and supporting new investigators to the HIV/AIDS research effort, especially young investigators beginning their career and also by encouraging the initiation of interdisciplinary research. This core will enhance all of these efforts by the following aims;1) To solicit, review and award pilot project grants with the goal of promoting innovative and collaborative and interdisciplinary research in HIV/AIDS. Funding will be for one year with a possible second year;awards will be prioritized for three groups: young HIV/AIDS investigators, new HIV/AIDS investigators and projects that promote interdisciplinary research, i.e., create linkages between investigators who are interested in social/behavioral, clinical and basic science research. 2) To develop and coordinate a mentoring system for young HIV/AIDS investigators. Interactions of a young investigator with an experienced and trusted advisor or group of advisors can aid in technical and non-technical decision making. This will be achieved by forming mentoring groups consisting of one primary established investigator with expertise in HIV/AIDS research and training along with additional mentors to provide needed expertise. Appropriate pairing of mentors with junior investigators will facilitate development of specific research directions and ideas, and enable positive critical feedback for potential manuscripts and grant proposals including NIH K or R award series. 3) To award travel grants to enable travel by trainees to present work at national meetings. Travel by trainees to scientific meetings in order to present work, meet potential collaborators and hear up-to-date presentations is a critical part of career development. The Developmental Core will be directed by Dr. Gregory Spear (RUMC) and co-directed by Dr. Ron Hershow (UIC). Dr. Spear is an experienced grant reviewer and is currently a regular member of the NIH/AIDS SBIR/STTR Biological Sciences Study Section. Dr. Hershow also has extensive experience reviewing NIH grants.

National Institute of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
Center Core Grants (P30)
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Special Emphasis Panel (ZAI1-SV-A)
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Rush University Medical Center
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Waluyo, Agung; Culbert, Gabriel J; Levy, Judith et al. (2015) Understanding HIV-related stigma among Indonesian nurses. J Assoc Nurses AIDS Care 26:69-80
Becker, James T; Kingsley, Lawrence A; Molsberry, Samantha et al. (2015) Cohort Profile: Recruitment cohorts in the neuropsychological substudy of the Multicenter AIDS Cohort Study. Int J Epidemiol 44:1506-16
Mackesy-Amiti, Mary Ellen; Donenberg, Geri R; Ouellet, Lawrence J (2014) Psychiatric correlates of injection risk behavior among young people who inject drugs. Psychol Addict Behav 28:1089-95
Ramirez-Valles, Jesus; Kuhns, Lisa M; Manjarrez, Dianna (2014) Tal Como Somos/just as we are: an educational film to reduce stigma toward gay and bisexual men, transgender individuals, and persons living with HIV/AIDS. J Health Commun 19:478-92
Meyer, Vanessa J; Little, Deborah M; Fitzgerald, Daniel A et al. (2014) Crack cocaine use impairs anterior cingulate and prefrontal cortex function in women with HIV infection. J Neurovirol 20:352-61
Spear, Gregory T; French, Audrey L; Gilbert, Douglas et al. (2014) Human ?-amylase present in lower-genital-tract mucosal fluid processes glycogen to support vaginal colonization by Lactobacillus. J Infect Dis 210:1019-28
Young, Jeremy D; Patel, Mahesh; Badowski, Melissa et al. (2014) Improved virologic suppression with HIV subspecialty care in a large prison system using telemedicine: an observational study with historical controls. Clin Infect Dis 59:123-6
Benning, Lorie; Golub, Elizabeth T; Anastos, Kathryn et al. (2014) Comparison of lower genital tract microbiota in HIV-infected and uninfected women from Rwanda and the US. PLoS One 9:e96844
Mata, Mariana M; Mahmood, Fareeha; Sowell, Ryan T et al. (2014) Effects of cryopreservation on effector cells for antibody dependent cell-mediated cytotoxicity (ADCC) and natural killer (NK) cell activity in (51)Cr-release and CD107a assays. J Immunol Methods 406:1-9
Kristoff, Jan; Haret-Richter, George; Ma, Dongzhu et al. (2014) Early microbial translocation blockade reduces SIV-mediated inflammation and viral replication. J Clin Invest 124:2802-6

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