Overall goals ofthe Basic Science Core includes: contributions to the National CFAR Mission, stimulating scientific collaboration in interdisciplinary and translational research, providing scientific leadership and institutional infrastructure dedicated to AIDS research, fostering scientific communication, sponsoring training and education, promoting knowledge of CFAR research findings and the importance of AIDS research through community outreach, promoting and supporting innovative NIH HIV/AIDS research initiatives, establishing collaborative research between CFARs, and supporting HIV/AIDS research networks, facilitating technology transfer and development through promotion of scientific interactions between CFARs and industry, and supporting research on prevention and treatment of HIV infection in hard-to-reach populations, especially in inner city, rural poor, and disadvantaged minorities. The mission ofthe Basic Science Core is to develop, refine, and provide training and services to HIV/AIDS investigators in DC for the assays used to evaluate and quantify HIV replication and gene expression, characterize HIV disease using immunologic, genomics and proteomics approaches, and facilitate drug development by providing small animal models of HIV disease. The assays, reagents, and training offered by this Core are designed to support basic, clinical, and translational research in the prevention, detection, and treatment of HIV infection and AIDS.
The aims i nclude: to provide technical support and laboratory services to promote HIV-related basic science research and translational studies through access to the following services and to provide mentorship and training opportunities for junior, minority and new HIV/AIDS investigators.
|Calabrese, Sarah K; Magnus, Manya; Mayer, Kenneth H et al. (2017) ""Support Your Client at the Space That They're in"": HIV Pre-Exposure Prophylaxis (PrEP) Prescribers' Perspectives on PrEP-Related Risk Compensation. AIDS Patient Care STDS 31:196-204|
|Farmer, Shu; Mindry, Deborah; Comulada, W Scott et al. (2017) Mobile Phone Ecological Momentary Assessment of Daily Stressors Among People Living With HIV: Elucidating Factors Underlying Health-Related Challenges in Daily Routines. J Assoc Nurses AIDS Care 28:737-751|
|Latkin, Carl A; Van Tieu, Hong; Fields, Sheldon et al. (2017) Social Network Factors as Correlates and Predictors of High Depressive Symptoms Among Black Men Who Have Sex with Men in HPTN 061. AIDS Behav 21:1163-1170|
|Rosenberg, Alana; Groves, Allison K; Blankenship, Kim M (2017) Comparing Black and White Drug Offenders: Implications for Racial Disparities in Criminal Justice and Reentry Policy and Programming. J Drug Issues 47:132-142|
|Pollack, Ross A; Jones, R Brad; Pertea, Mihaela et al. (2017) Defective HIV-1 Proviruses Are Expressed and Can Be Recognized by Cytotoxic T Lymphocytes, which Shape the Proviral Landscape. Cell Host Microbe 21:494-506.e4|
|Paquin-Proulx, D; Ching, C; Vujkovic-Cvijin, I et al. (2017) Bacteroides are associated with GALT iNKT cell function and reduction of microbial translocation in HIV-1 infection. Mucosal Immunol 10:69-78|
|Xia, Jie; Feng, Bo; Shao, Qianhang et al. (2017) Virtual Screening against Phosphoglycerate Kinase 1 in Quest of Novel Apoptosis Inhibitors. Molecules 22:|
|Castel, Amanda D; Kuo, Irene; Mikre, Meriam et al. (2017) Feasibility of Using HIV Care-Continuum Outcomes to Identify Geographic Areas for Targeted HIV Testing. J Acquir Immune Defic Syndr 74 Suppl 2:S96-S103|
|Raposo, Rui André Saraiva; de Mulder Rougvie, Miguel; Paquin-Proulx, Dominic et al. (2017) IFITM1 targets HIV-1 latently infected cells for antibody-dependent cytolysis. JCI Insight 2:e85811|
|Xia, Jie; Hsieh, Jui-Hua; Hu, Huabin et al. (2017) The Development of Target-Specific Pose Filter Ensembles To Boost Ligand Enrichment for Structure-Based Virtual Screening. J Chem Inf Model 57:1414-1425|
Showing the most recent 10 out of 160 publications