The Rodent Histopathology Core has been approved and funded by the CCSG since the first consortium application in 2000. The Core provides high priority, quality access to services for Cancer Center members. While many commercial and academic histology services are available, no other facility is available that offers comparable quality with rapid turnaround and highly experienced professional supervision and investigator education. The Core provides the initial interpretation and understanding of an animal model and interprets this phenotype in the context of the genetic manipulation. Murine models of cancer have provided investigators with a unique opportunity to understand tumor cell biology in the setting of intricate and dynamic physiological systems. This includes the ability to not only investigate the role of specific oncogenes, tumor suppressor genes and signaling pathways in tumorigenesis, but, in contrast to in vitro systems, the interactions between the tumor and it's environment can be studied as well. Director: Peter Howley, MD, MMS(HMS) Category: 1.05 (Animal Health (Pathology/Histology)) Management: Joint (Cancer Center and Institutional)

Public Health Relevance

The Core provides Cancer Center members with high quality professional, technical, and educational pathology services, supporting investigator research that leads to the identification of pathologic processes in mice that can be directly translatable to human disease.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA006516-48
Application #
8469430
Study Section
Subcommittee G - Education (NCI)
Project Start
Project End
Budget Start
2012-12-01
Budget End
2013-11-30
Support Year
48
Fiscal Year
2013
Total Cost
$203,696
Indirect Cost
$63,430
Name
Dana-Farber Cancer Institute
Department
Type
DUNS #
076580745
City
Boston
State
MA
Country
United States
Zip Code
02215
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