OF SHARED RESOURCE The Sidney Kimmel Comprehensive Cancer Center (SKCCC) Biostatistics Shared Resource (BiostatSR) consists of six doctoral-level faculty biostatisticians positions, one of which is in the process of being filled, four master's level statisticians, and two information technology specialists. BiostatSR members collaborate and consult with other Cancer Center investigators in the design, conduct, and analysis of cancer-related clinical, preclinical, laboratory, and epidemiologic investigations. BiostatSR also reviews proposals for cancer-related clinical investigations in the Protocol Review and Monitoring System-Clinical Research Review Committee (PRMS-CRC). The Biostatistics Core provides consultation and expertise regarding study design (including validity of the overall design, feasibility of meeting objectives, sample size and projection of study duration), recommendations for and development of key infrastructure (data management and computer systems support), data analysis, preparation of reports and assistance with manuscript writing, and development of new biostatistical methods if required by the project. The goal of the Biostatistics Core is to ensure that study designs, data monitoring, and analyses use state-of-the-art methods, and to help developmental studies supported by the Center garner peer-reviewed funding. This Core has experienced turnover in faculty during the grant cycle, most of whom have successfully been replaced, with a plan to undergo controlled growth during the next grant cycle amongst both faculty and staff. In addition to being strongly integrated into all Programs in the Center, biostatisticians in the Core have important intellectual ties to other professionals in the medical institutions who are engaged in similar activities in other disciplines. This diverse environment provides SKCCC investigators with strong, broad-based biostatistical expertise that is always accessible Plans for the future of Biostatistics include collaboration in initiatives in information systems to support clinical and basic science research data, and development of a centerwide Program in quantitative cancer research. Lay: This Core provides consultation and expertise regarding study design, recommendations for and development of key infrastructure, data analysis, preparation of reports and assistance with manuscript writing, and development of new biostatistical methods if required by the project. Cancer Center Managed Shared Resource Current Grant Year Reporting Period: January 1, 2010 to December 31, 2010 .

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA006973-51
Application #
8661000
Study Section
Subcommittee G - Education (NCI)
Project Start
Project End
Budget Start
2014-05-01
Budget End
2015-04-30
Support Year
51
Fiscal Year
2014
Total Cost
$545,321
Indirect Cost
$209,387
Name
Johns Hopkins University
Department
Type
DUNS #
001910777
City
Baltimore
State
MD
Country
United States
Zip Code
21218
Hurley, Paula J; Sundi, Debasish; Shinder, Brian et al. (2016) Germline Variants in Asporin Vary by Race, Modulate the Tumor Microenvironment, and Are Differentially Associated with Metastatic Prostate Cancer. Clin Cancer Res 22:448-58
Roberts, Nicholas J; Norris, Alexis L; Petersen, Gloria M et al. (2016) Whole Genome Sequencing Defines the Genetic Heterogeneity of Familial Pancreatic Cancer. Cancer Discov 6:166-75
Chen, Zhihang; Penet, Marie-France; Krishnamachary, Balaji et al. (2016) PSMA-specific theranostic nanoplex for combination of TRAIL gene and 5-FC prodrug therapy of prostate cancer. Biomaterials 80:57-67
Castanares, Mark A; Copeland, Ben T; Chowdhury, Wasim H et al. (2016) Characterization of a novel metastatic prostate cancer cell line of LNCaP origin. Prostate 76:215-25
Anders, Nicole M; Wanjiku, Teresia M; He, Ping et al. (2016) A robust and rapid liquid chromatography tandem mass spectrometric method for the quantitative analysis of 5-azacytidine. Biomed Chromatogr 30:494-6
Morgan, Michael T; Haj-Yahya, Mahmood; Ringel, Alison E et al. (2016) Structural basis for histone H2B deubiquitination by the SAGA DUB module. Science 351:725-8
Mao, Kai; Liu, Jieqiong; Sun, Jian et al. (2016) Patterns and prognostic value of lymph node dissection for resected perihilar cholangiocarcinoma. J Gastroenterol Hepatol 31:417-26
Morais, Carlos L; Guedes, Liana B; Hicks, Jessica et al. (2016) ERG and PTEN status of isolated high-grade PIN occurring in cystoprostatectomy specimens without invasive prostatic adenocarcinoma. Hum Pathol 55:117-25
Wang, Zhijun; Hansis, Eberhard; Chen, Rongxin et al. (2016) Automatic bone removal for 3D TACE planning with C-arm CBCT: Evaluation of technical feasibility. Minim Invasive Ther Allied Technol 25:162-70
Vrooman, Lynda M; Kirov, Ivan I; Dreyer, ZoAnn E et al. (2016) Activity and Toxicity of Intravenous Erwinia Asparaginase Following Allergy to E. coli-Derived Asparaginase in Children and Adolescents With Acute Lymphoblastic Leukemia. Pediatr Blood Cancer 63:228-33

Showing the most recent 10 out of 1943 publications