The Behavioral Research Methods (BRM) Core Facility enhances the scientific objectives of the Center's programs by assisting MSKCC investigators with the design, implementation and execution of research involving the capture of health-related quality-of-life (HRQoL) and/or patient-reported outcome (PRO) data. The faculty of the BRM Core are nationally recognized social and behavioral sciences experts who provide technical assistance to all users throughout their various stages of research, including grant and protocol development, research study assistant and support staff training, and sample identification. The BRM Core Facility assists investigators by providing the following specific services and technical support functions: 1) selection, analysis, and interpretation of psychometrically sound assessment tools (provider surveys, semi-structured interviews, patient-reporting instruments, and observer ratings) for the measurement of quality of life, health behavior change, treatment toxicities, and other psychosocial outcomes; 2) consultation regarding the development and implementation of research methodologies consistent with best practices in psychosocial and behavioral research in cancer; 3) qualitative Interview, focus group methodology, and other process evaluation techniques for developing new psychosocial instruments and generating new testable hypotheses; 4) training and trouble-shooting with regard to patient Interviewing methods, survey data collection, and human subjects' issues for research support staff conducting quality of life and behavioral/psychosocial studies; and 5) methodological support for research on minority populations in clinical trials, community interventions, and population-based research. The BRM Core Facility maintains an extensive resource library of electronic psychosocial and behavioral measures and research method protocols commonly used in cancer prevention and control research. The services provided by the BRM Core have supported the research of 20 investigators in the past year. During the past grant period the work Of the Core has contributed to 190 publications of researchers.
Methodological advances in the behavioral and social sciences are widely recognized as germane to translational research in cancer prevention, early detection, treatment, palliative care, and survivorship. Additionally, the NCI and the FDA acknowledge that patient-reported outcome data is the gold standard for the capture of the patient experience.
|Pak, Linda M; Gonen, Mithat; Seier, Kenneth et al. (2018) Can physician gestalt predict survival in patients with resectable pancreatic adenocarcinoma? Abdom Radiol (NY) 43:2113-2118|
|Thomas, Rozario; Marks, Daniel Henry; Chin, Yvette et al. (2018) Whole chromosome loss and associated breakage-fusion-bridge cycles transform mouse tetraploid cells. EMBO J 37:201-218|
|Shoag, Jonathan; Liu, Deli; Blattner, Mirjam et al. (2018) SPOP mutation drives prostate neoplasia without stabilizing oncogenic transcription factor ERG. J Clin Invest 128:381-386|
|Abreu, Carla M; Prakash, Rohit; Romanienko, Peter J et al. (2018) Shu complex SWS1-SWSAP1 promotes early steps in mouse meiotic recombination. Nat Commun 9:3961|
|Katsoulakis, Evangelia; Leeman, Jonathan E; Lok, Benjamin H et al. (2018) Long-term outcomes in oral cavity squamous cell carcinoma with adjuvant and salvage radiotherapy after surgery. Laryngoscope 128:2539-2545|
|Huicochea Castellanos, Sandra; Corrias, Giuseppe; Ulaner, Gary A et al. (2018) Detection of recurrent pancreatic cancer: value of second-opinion interpretations of cross-sectional images by subspecialized radiologists. Abdom Radiol (NY) :|
|Hoseini, Sayed Shahabuddin; Guo, Hongfen; Wu, Zhihao et al. (2018) A potent tetravalent T-cell-engaging bispecific antibody against CD33 in acute myeloid leukemia. Blood Adv 2:1250-1258|
|Attiyeh, Marc A; Fernández-Del Castillo, Carlos; Al Efishat, Mohammad et al. (2018) Development and Validation of a Multi-institutional Preoperative Nomogram for Predicting Grade of Dysplasia in Intraductal Papillary Mucinous Neoplasms (IPMNs) of the Pancreas: A Report from The Pancreatic Surgery Consortium. Ann Surg 267:157-163|
|Tollinche, Luis; Tan, KaySee; Han, Austin et al. (2018) Analyzing Volatile Anesthetic Consumption by Auditing Fresh Gas Flow: An Observational Study at an Academic Hospital. Int J Anesth Anesth 5:|
|Tadros, Audree B; Wen, Hannah Y; Morrow, Monica (2018) Breast Cancers of Special Histologic Subtypes Are Biologically Diverse. Ann Surg Oncol 25:3158-3164|
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