Since the last CCSG review, AECC has undertaken an intensive and ongoing process of planning and evaluation. Intrinsic to this process vi/as: (i) the AECC Steering Committees consisting of all program leaders, Executive Committee members, leaders of the major clinical oncology services, and other key College and AECC faculty and (ii) The External Scientific Advisory Committee (ESAC) which consists of eleven members with expertise relevant to AECC research programs and their administration. In addition, ad hoc members were included at ESAC meetings to provide special expertise in guiding the implementation of a developing Cancer Prevention and Control program. In June 2008, there was a major planning retreat that culminated in the formulation of a Strategic Plan. The overarching strategic objectives that emerged at this retreat were to improve AECC's structure to optimally harness the strong basic science elements in AECC programs in order to enhance clinical/translational research, to strengthen the clinical research enterprise, and to expand population research which, collectively, would enhance the comprehensive nature of this center ultimately leading to comprehensive designation. Major programmatic goals that emerged from the June 2008 retreat were: (i) to strengthen the clinical oncology services at MMC with the recruitment of a cadre of committed clinician/researchers, (ii) to create the position of Associate Director for Clinical Services at MMC in order to establish a multidisciplinary clinical structure at MMC that encompasses all the oncology and support services, (iii) to review the AECC programmatic structure in order to identify ways to enhance its disease focus and translational capabilities, and to (iv) build behavioral sciences with the objective of ultimately establishing a Cancer Prevention and Control Program. Intrinsic to the plan was strengthening and broadening the scope of basic research at the Center leveraging College and AECC resources. Another important element in the Planning and Evaluation process was the annual off-campus """"""""Advances"""""""" meeting when the scientific thrust and collaborations among working groups and individual investigators, and their integration into the programmatic structure of the Center, could be evaluated and new needed research areas and technologies identified. Developments Funds were targeted based upon needs identified within the context of the Planning and Evaluation process. Support is requested for travel and consultation fees for external advisors and for the annual """"""""Advances"""""""" off-campus retreat of the entire AECC membership and for planning retreats of the AECC leadership.

Public Health Relevance

Planning and evaluation funds support both external and internal advisory and evaluation activities centered the development of our scientific activities in support of the translational research mission and goals of the Albert Einstein Cancer Center (AECC). As an NCI-designated Cancer Center, AECC contributes to the national effort to reduce morbidity and mortality from cancer.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA013330-41
Application #
8753324
Study Section
Subcommittee B - Comprehensiveness (NCI)
Project Start
Project End
Budget Start
2014-07-01
Budget End
2015-06-30
Support Year
41
Fiscal Year
2014
Total Cost
Indirect Cost
Name
Albert Einstein College of Medicine
Department
Type
DUNS #
City
Bronx
State
NY
Country
United States
Zip Code
10461
Mao, Serena P H; Park, Minji; Cabrera, Ramon M et al. (2018) Loss of amphiregulin reduces myoepithelial cell coverage of mammary ducts and alters breast tumor growth. Breast Cancer Res 20:131
Mocholi, Enric; Dowling, Samuel D; Botbol, Yair et al. (2018) Autophagy Is a Tolerance-Avoidance Mechanism that Modulates TCR-Mediated Signaling and Cell Metabolism to Prevent Induction of T Cell Anergy. Cell Rep 24:1136-1150
Yang, Chia-Ping Huang; Wang, Changwei; Ojima, Iwao et al. (2018) Taxol Analogues Exhibit Differential Effects on Photoaffinity Labeling of ?-Tubulin and the Multidrug Resistance Associated P-Glycoprotein. J Nat Prod 81:600-606
Guan, Fangxia; Tabrizian, Tahmineh; Novaj, Ardijana et al. (2018) Dietary Walnuts Protect Against Obesity-Driven Intestinal Stem Cell Decline and Tumorigenesis. Front Nutr 5:37
Wang, Tao; Hosgood, H Dean; Lan, Qing et al. (2018) The Relationship Between Population Attributable Fraction and Heritability in Genetic Studies. Front Genet 9:352
Chennamadhavuni, Divya; Saavedra-Avila, Noemi Alejandra; Carreño, Leandro J et al. (2018) Dual Modifications of ?-Galactosylceramide Synergize to Promote Activation of Human Invariant Natural Killer T Cells and Stimulate Anti-tumor Immunity. Cell Chem Biol 25:571-584.e8
Limi, Saima; Senecal, Adrien; Coleman, Robert et al. (2018) Transcriptional burst fraction and size dynamics during lens fiber cell differentiation and detailed insights into the denucleation process. J Biol Chem 293:13176-13190
Rocha, Agostinho G; Franco, Antonietta; Krezel, Andrzej M et al. (2018) MFN2 agonists reverse mitochondrial defects in preclinical models of Charcot-Marie-Tooth disease type 2A. Science 360:336-341
Cabahug-Zuckerman, Pamela; Stout Jr, Randy F; Majeska, Robert J et al. (2018) Potential role for a specialized ?3 integrin-based structure on osteocyte processes in bone mechanosensation. J Orthop Res 36:642-652
Vilchèze, Catherine; Copeland, Jacqueline; Keiser, Tracy L et al. (2018) Rational Design of Biosafety Level 2-Approved, Multidrug-Resistant Strains of Mycobacterium tuberculosis through Nutrient Auxotrophy. MBio 9:

Showing the most recent 10 out of 1508 publications