The Integrative Genomics and Bioinformatics Core (IGC) specializes in the analysis of next-generation sequencing and other high-throughput genomics data. The IGC was established to assist the Salk community with the integration of genomics data into their research. The primary focus of the core is to provide analysis support for next-generation sequencing applications. The IGC offers a variety of services to suit the needs of different research groups, but is also committed to providing customized assistance to maintain the highest levels of scientific achievement for Salk researchers. All CCSG supported core are organized into one group: Basic Research. This shared resource is catagorized as category (7.02) Bioinformatics in summary 1D
Data about cell function, particularly genomics data, is expanding dramatically. This resource will provide Cancer Center investigators with access to state-of-the-art bioinformatics and genomics analysis.
| Ogawa, Junko; Pao, Gerald M; Shokhirev, Maxim N et al. (2018) Glioblastoma Model Using Human Cerebral Organoids. Cell Rep 23:1220-1229 |
| Ahmadian, Maryam; Liu, Sihao; Reilly, Shannon M et al. (2018) ERR? Preserves Brown Fat Innate Thermogenic Activity. Cell Rep 22:2849-2859 |
| Benegiamo, Giorgia; Mure, Ludovic S; Erikson, Galina et al. (2018) The RNA-Binding Protein NONO Coordinates Hepatic Adaptation to Feeding. Cell Metab 27:404-418.e7 |
| Sulli, Gabriele; Rommel, Amy; Wang, Xiaojie et al. (2018) Pharmacological activation of REV-ERBs is lethal in cancer and oncogene-induced senescence. Nature 553:351-355 |
| Yoon, Young-Sil; Tsai, Wen-Wei; Van de Velde, Sam et al. (2018) cAMP-inducible coactivator CRTC3 attenuates brown adipose tissue thermogenesis. Proc Natl Acad Sci U S A 115:E5289-E5297 |
| Xia, Yifeng; Zhan, Cheng; Feng, Mingxiang et al. (2018) Targeting CREB Pathway Suppresses Small Cell Lung Cancer. Mol Cancer Res 16:825-832 |
| Stern, S; Santos, R; Marchetto, M C et al. (2018) Neurons derived from patients with bipolar disorder divide into intrinsically different sub-populations of neurons, predicting the patients' responsiveness to lithium. Mol Psychiatry 23:1453-1465 |
| Limpert, Allison S; Lambert, Lester J; Bakas, Nicole A et al. (2018) Autophagy in Cancer: Regulation by Small Molecules. Trends Pharmacol Sci 39:1021-1032 |
| Mure, Ludovic S; Le, Hiep D; Benegiamo, Giorgia et al. (2018) Diurnal transcriptome atlas of a primate across major neural and peripheral tissues. Science 359: |
| Lu, Zhimin; Hunter, Tony (2018) Metabolic Kinases Moonlighting as Protein Kinases. Trends Biochem Sci 43:301-310 |
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