The University of Chicago Cancer Research Center (UCCRC) is a formal academic unit with departmental status within the Division of the Biological Sciences (BSD). The Director has department chair status and sits on the Division's governing bodies. The Director has control over administrative and research space, fiscal responsibility for the CCSG, American Cancer Society Institutional Research Grant (ACS-IRG), caBIG contract with NCI, philanthropic funds raised by the University of Chicago Cancer Research Foundation (UCCRF), and interdepartmental/interdisciplinary grants >$500,000 annual direct costs. The Director has authority over UCCRC membership and appointments, direct and shared authority over shared resources, and full authority over UCCRC philanthropic activities. Under the leadership of Dr. Marcy List, Associate Director for Administration, the UCCRC is responsible for managing all of these activities as they relate to both the administrative needs of the UCCRC, and the research operations of the 198 UCCRC investigators. The UCCRC administrative unit is subdivided into seven subunits: Finances and Human Resources*, Informatics, Grant and Program Development, Clinical TrialsA, Fundraising*, Communications*, and the Cancer Resource Center* (* indicates no CCSG funds requested;A described in Section 9.1.13). The Financial Unit (Director for Finance plus 2 additional FTE's) is responsible for all pre- and post-award activities for over $5.5 million (annual direct costs) in federal and non-federal grants and contracts, and $9.3 million in philanthropic funds, and the allocation of UCCRC funds through RFA's. At present, the office manages a SPORE grant, a Leukemia and Lymphoma Society SCOR, the CCSG, the ACS-IRG, caBIG contract, and numerous foundation accounts. The Informatics Unit (Director for Informatics plus 5 additional FTE's) is responsible for all informatics and database support for UCCRC administrative units, the CCTO and UCCRC investigators as well as coordinating UCCRC IT activities with those of the BSD and University of Chicago Medical Center, and supporting the UCCRC Website. Four FTE's are responsible for Grant and Program Development Support, which includes all non-financial pre- and post-award support for large cancer-related grants (in the past 3 years, this group has been responsible for the submission of the CCSG, ACS-IRG, 4 SPORE applications, 2 SCOR applications, and 1 Tumor Microenvironment Network application);coordination of program and overall UCCRC development, planning and evaluation activities; and coordination of activities related to membership and recruitment. These activities represent a significant expansion of UCCRC responsibilities, with a parallel increase in staff.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA014599-37
Application #
8375699
Study Section
Special Emphasis Panel (ZCA1-RTRB-N)
Project Start
Project End
Budget Start
2012-04-01
Budget End
2013-03-31
Support Year
37
Fiscal Year
2012
Total Cost
$342,756
Indirect Cost
$119,817
Name
University of Chicago
Department
Type
DUNS #
005421136
City
Chicago
State
IL
Country
United States
Zip Code
60637
Li, Gang; Montgomery, Jeffrey E; Eckert, Mark A et al. (2017) An activity-dependent proximity ligation platform for spatially resolved quantification of active enzymes in single cells. Nat Commun 8:1775
Stoddart, Angela; Wang, Jianghong; Hu, Chunmei et al. (2017) Inhibition of WNT signaling in the bone marrow niche prevents the development of MDS in the Apcdel/+ MDS mouse model. Blood 129:2959-2970
Wing, Claudia; Komatsu, Masaaki; Delaney, Shannon M et al. (2017) Application of stem cell derived neuronal cells to evaluate neurotoxic chemotherapy. Stem Cell Res 22:79-88
Shah, Palak; Trinh, Elaine; Qiang, Lei et al. (2017) Arsenic Induces p62 Expression to Form a Positive Feedback Loop with Nrf2 in Human Epidermal Keratinocytes: Implications for Preventing Arsenic-Induced Skin Cancer. Molecules 22:
Qiang, Lei; Sample, Ashley; Shea, Christopher R et al. (2017) Autophagy gene ATG7 regulates ultraviolet radiation-induced inflammation and skin tumorigenesis. Autophagy 13:2086-2103
Morita, Shuhei; Villalta, S Armando; Feldman, Hannah C et al. (2017) Targeting ABL-IRE1? Signaling Spares ER-Stressed Pancreatic ? Cells to Reverse Autoimmune Diabetes. Cell Metab 25:1207
Davis, Trevor L; Rebay, Ilaria (2017) Antagonistic regulation of the second mitotic wave by Eyes absent-Sine oculis and Combgap coordinates proliferation and specification in the Drosophila retina. Development 144:2640-2651
Kathayat, Rahul S; Elvira, Pablo D; Dickinson, Bryan C (2017) A fluorescent probe for cysteine depalmitoylation reveals dynamic APT signaling. Nat Chem Biol 13:150-152
Hu, Xue; Li, Li; Yu, Xinyi et al. (2017) CRISPR/Cas9-mediated reversibly immortalized mouse bone marrow stromal stem cells (BMSCs) retain multipotent features of mesenchymal stem cells (MSCs). Oncotarget 8:111847-111865
Hasan, Yasmin; Waller, Joseph; Yao, Katharine et al. (2017) Utilization trend and regimens of hypofractionated whole breast radiation therapy in the United States. Breast Cancer Res Treat 162:317-328

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