The mission of the Virginia Commonwealth University (VCU) Massey Cancer Center (MCC) Clinical Research Shared Resource (CRSR) is to support the development and conduct of cancer clinical research and, in particular, clinical trials at the institution. This shared resource is one of the original shared resources established with the Cancer Center Support Grant (CCSG) awarded in 1976. The CRSR provides the following services to all MCC members conducting cancer clinical trials: regulatory compliance, subject recruitment, protocol compliance, data collection and reporting, quality assurance, information dissemination, and reporting on clinical trials activity. In addition, the CRSR provides project management and development of MCC investigator-initiated clinical trials from concept development through activation. The CRSR includes Research Nurses (RNs), Clinical Research Associates (CRAs), Regulatory Coordinators, Quality Control (QC) Coordinator, IT staff. Affiliations Coordinators, and Minority Recruitment staff. Personnel supported by CCSG Protocol-Specific Research (PSR) are in the CRSR.

Public Health Relevance

The Clinical Research Shared Resource provides the infrastructure needed to support the development and conduct of clinical cancer research at MCC. This support helps ensure that clinical trials are developed in an efficient manner, are conducted in compliance with all regulatory requirements, that appropriate data is collected, and that the results are reported in a timely manner.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA016059-33
Application #
8662712
Study Section
Subcommittee B - Comprehensiveness (NCI)
Project Start
Project End
Budget Start
2014-05-01
Budget End
2015-04-30
Support Year
33
Fiscal Year
2014
Total Cost
Indirect Cost
Name
Virginia Commonwealth University
Department
Type
DUNS #
City
Richmond
State
VA
Country
United States
Zip Code
23298
Ma, Yibao; Min, Hae-Ki; Oh, Unsong et al. (2017) The lignan manassantin is a potent and specific inhibitor of mitochondrial complex I and bioenergetic activity in mammals. J Biol Chem 292:20989-20997
van der Weyden, Louise; Arends, Mark J; Campbell, Andrew D et al. (2017) Genome-wide in vivo screen identifies novel host regulators of metastatic colonization. Nature 541:233-236
Schurman, Lesley D; Smith, Terry L; Morales, Anthony J et al. (2017) Investigation of left and right lateral fluid percussion injury in C57BL6/J mice: In vivo functional consequences. Neurosci Lett 653:31-38
Newton, Jason; Hait, Nitai C; Maceyka, Michael et al. (2017) FTY720/fingolimod increases NPC1 and NPC2 expression and reduces cholesterol and sphingolipid accumulation in Niemann-Pick type C mutant fibroblasts. FASEB J 31:1719-1730
Manzanares, Miguel Á; Usui, Akihiro; Campbell, Deanna J et al. (2017) Transforming Growth Factors ? and ? Are Essential for Modeling Cholangiocarcinoma Desmoplasia and Progression in a Three-Dimensional Organotypic Culture Model. Am J Pathol 187:1068-1092
Arsenovic, Paul T; Mayer, Carl R; Conway, Daniel E (2017) SensorFRET: A Standardless Approach to Measuring Pixel-based Spectral Bleed-through and FRET Efficiency using Spectral Imaging. Sci Rep 7:15609
Lownik, Joseph C; Luker, Andrea J; Damle, Sheela R et al. (2017) ADAM10-Mediated ICOS Ligand Shedding on B Cells Is Necessary for Proper T Cell ICOS Regulation and T Follicular Helper Responses. J Immunol 199:2305-2315
Karki, Kishor; Saraiya, Siddharth; Hugo, Geoffrey D et al. (2017) Variabilities of Magnetic Resonance Imaging-, Computed Tomography-, and Positron Emission Tomography-Computed Tomography-Based Tumor and Lymph Node Delineations for Lung Cancer Radiation Therapy Planning. Int J Radiat Oncol Biol Phys 99:80-89
Meier, Jeremy A; Hyun, Moonjung; Cantwell, Marc et al. (2017) Stress-induced dynamic regulation of mitochondrial STAT3 and its association with cyclophilin D reduce mitochondrial ROS production. Sci Signal 10:
Benson, Zachary; Manjili, Saeed H; Habibi, Mehran et al. (2017) Conditioning neoadjuvant therapies for improved immunotherapy of cancer. Biochem Pharmacol 145:12-17

Showing the most recent 10 out of 499 publications