The long-term mission of the Genome Technology Center (GTC) is to enable and foster institutional science by providing advanced expertise in genomics, centralized state-of-the-art resources, and the training necessary to promote cutting-edge basic, clinical and translational cancer research through dedicated collaborative effort. GTC provides a modern environment that facilitates cross-talk between researchers from diverse fields such as biology, development, clinical research, chemistry and bioinformatics. GTC maintains and provides affordable access to technologically advanced instrumentation including multiple platforms for massively parallel sequencing and microarray profiling, and it creates an educational environment to instruct faculty, staff, fellows, and students on how these technologies can positively advance their research, prepare successful grant applications and publish highly competitive results. GTC also directly assists investigators with the presentation and successful publication of their data. To achieve the specific aims and all aspects of the investigator's cancer-oriented projects, GTC frequently and actively collaborates with additional NYUCI shared resources including the BioRepository Center, Experimental Pathology and the Biomedical Informatics Shared Resource.

Public Health Relevance

The relevance of the Genome Technology Center to the public health lies in its significant contribution to general understanding of molecular mechanisms underlying human malignancies and to the future development of successful therapeutic approaches against human cancers. To that end, the GTC assists over 120 NYULMC laboratories to advance their basic, clinical and translational research.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA016087-34
Application #
8765178
Study Section
Subcommittee G - Education (NCI)
Project Start
Project End
Budget Start
2014-03-01
Budget End
2015-02-28
Support Year
34
Fiscal Year
2014
Total Cost
$118,998
Indirect Cost
$48,793
Name
New York University
Department
Type
DUNS #
121911077
City
New York
State
NY
Country
United States
Zip Code
10016
Puranik, Amrutesh S; Leaf, Irina A; Jensen, Mark A et al. (2018) Kidney-resident macrophages promote a proangiogenic environment in the normal and chronically ischemic mouse kidney. Sci Rep 8:13948
Saint Fleur-Lominy, Shella; Maus, Mate; Vaeth, Martin et al. (2018) STIM1 and STIM2 Mediate Cancer-Induced Inflammation in T Cell Acute Lymphoblastic Leukemia. Cell Rep 24:3045-3060.e5
Cui, Xin; Morales, Renee-Tyler Tan; Qian, Weiyi et al. (2018) Hacking macrophage-associated immunosuppression for regulating glioblastoma angiogenesis. Biomaterials 161:164-178
Weng, Mao-Wen; Lee, Hyun-Wook; Park, Sung-Hyun et al. (2018) Aldehydes are the predominant forces inducing DNA damage and inhibiting DNA repair in tobacco smoke carcinogenesis. Proc Natl Acad Sci U S A 115:E6152-E6161
Burgess, Hannah M; Pourchet, Aldo; Hajdu, Cristina H et al. (2018) Targeting Poxvirus Decapping Enzymes and mRNA Decay to Generate an Effective Oncolytic Virus. Mol Ther Oncolytics 8:71-81
Wong, Serre-Yu; Coffre, Maryaline; Ramanan, Deepshika et al. (2018) B Cell Defects Observed in Nod2 Knockout Mice Are a Consequence of a Dock2 Mutation Frequently Found in Inbred Strains. J Immunol 201:1442-1451
Handler, Jesse; Cullis, Jane; Avanzi, Antonina et al. (2018) Pre-neoplastic pancreas cells enter a partially mesenchymal state following transient TGF-? exposure. Oncogene 37:4334-4342
Diamond, Julie M; Vanpouille-Box, Claire; Spada, Sheila et al. (2018) Exosomes Shuttle TREX1-Sensitive IFN-Stimulatory dsDNA from Irradiated Cancer Cells to DCs. Cancer Immunol Res 6:910-920
Fan, Xiaozhou; Peters, Brandilyn A; Jacobs, Eric J et al. (2018) Drinking alcohol is associated with variation in the human oral microbiome in a large study of American adults. Microbiome 6:59
Chen, Danqi; Fang, Lei; Mei, Shenglin et al. (2018) Erratum: ""Regulation of Chromatin Assembly and Cell Transformation by Formaldehyde Exposure in Human Cells"". Environ Health Perspect 126:019001

Showing the most recent 10 out of 1170 publications