PRECLINICAL IMAGING LABORATORY (PCI) The mission of the Preclinical Imaging Laboratory Shared Resource (PCI) shared resource is to enable and foster cutting edge research by providing highly specialized expertise and full services for small animal imaging in a collaborative environment. A new PCC Shared Resource, PCI was initially established at NYU School of Medicine (NYUSoM) in 2011 in response to the growing demands for imaging instruments and additional imaging modalities by NYUSoM biomedical research community. This was achieved by consolidating existing imaging installations as part of the mouse imaging core successfully operated since 1997. Further institutional investment led to the acquisition of additional scanners and to the diversification of imaging modalities to serve NYU researchers, and in particular PCC investigators. Under the expert direction of Dr. Yousseff Wadghiri, PCI provides rodent imaging modalities equivalent to those available for human patients.
The Specific Aims of PCI are:
Aim 1) To provide expertise in and access to small animal imaging, including MRI, PET/CT, ultrasound, bioluminescence and fluorescence imaging;
Aim 2) To provide technical assistance and training to all PCC investigators using imaging modalities;
Aim 3) To provide technical support for data analysis and data sharing;
Aim 4) To evaluate and implement novel imaging technologies and modalities.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
2P30CA016087-38
Application #
9633413
Study Section
Subcommittee I - Transistion to Independence (NCI)
Project Start
Project End
2024-02-29
Budget Start
2019-03-01
Budget End
2020-02-29
Support Year
38
Fiscal Year
2019
Total Cost
Indirect Cost
Name
New York University
Department
Type
DUNS #
121911077
City
New York
State
NY
Country
United States
Zip Code
10016
Winer, Benjamin Y; Shirvani-Dastgerdi, Elham; Bram, Yaron et al. (2018) Preclinical assessment of antiviral combination therapy in a genetically humanized mouse model for hepatitis delta virus infection. Sci Transl Med 10:
Ruggles, Kelly V; Wang, Jincheng; Volkova, Angelina et al. (2018) Changes in the Gut Microbiota of Urban Subjects during an Immersion in the Traditional Diet and Lifestyle of a Rainforest Village. mSphere 3:
MariƩ, Isabelle J; Chang, Hao-Ming; Levy, David E (2018) HDAC stimulates gene expression through BRD4 availability in response to IFN and in interferonopathies. J Exp Med 215:3194-3212
Gupta, Ankit; Xu, Jing; Lee, Shirley et al. (2018) Facile target validation in an animal model with intracellularly expressed monobodies. Nat Chem Biol 14:895-900
Lee, Hyun-Wook; Park, Sung-Hyun; Weng, Mao-Wen et al. (2018) E-cigarette smoke damages DNA and reduces repair activity in mouse lung, heart, and bladder as well as in human lung and bladder cells. Proc Natl Acad Sci U S A 115:E1560-E1569
Evensen, Nikki A; Madhusoodhan, P Pallavi; Meyer, Julia et al. (2018) MSH6 haploinsufficiency at relapse contributes to the development of thiopurine resistance in pediatric B-lymphoblastic leukemia. Haematologica 103:830-839
Formenti, Silvia C; Rudqvist, Nils-Petter; Golden, Encouse et al. (2018) Radiotherapy induces responses of lung cancer to CTLA-4 blockade. Nat Med 24:1845-1851
Sun, Qi; Rabbani, Piul; Takeo, Makoto et al. (2018) Dissecting Wnt Signaling for Melanocyte Regulation during Wound Healing. J Invest Dermatol 138:1591-1600
Gagner, Jean-Pierre; Zagzag, David (2018) Probing Glioblastoma Tissue Heterogeneity with Laser Capture Microdissection. Methods Mol Biol 1741:209-220
Xu, Yang; Taylor, Paul; Andrade, Joshua et al. (2018) Pathologic Oxidation of PTPN12 Underlies ABL1 Phosphorylation in Hereditary Leiomyomatosis and Renal Cell Carcinoma. Cancer Res 78:6539-6548

Showing the most recent 10 out of 1170 publications