In this Cancer Center Support Grant renewal proposal, the American Health Foundation requests continuing support of its Cancer Center activities. The American Health Foundation Cancer Center is a basic research center which is unique in its emphasis on cancer prevention and control. The Center features a highly interdisciplinary approach combining epidemiologic investigations, basic laboratory studies in cancer etiology, and cancer control activities. Since most of the American Health Foundation's support is derived from peer-reviewed National Cancer Institute grants and contracts, the parent organization and the Cancer Center are virtually identical. The Center's research is focused upon prevention of the major human cancers with particular emphasis on tobacco-related cancers such as lung, oral cavity, esophagus, cervix, and pancreas; and nutritionally-linked cancers such as breast, prostate, and colon. This research is carried out in five interactive major programs: Interdisciplinary Studies in Cancer Epidemiology, Tobacco Carcinogenesis, Chemical Carcinogenesis, Nutritional Carcinogenesis and Chemoprevention, and Cancer Prevention and Control Among Special Populations. Center activities also include a developing program in Molecular Toxicology as well as research projects in biochemical pharmacology and nutritional endocrinology. The research in these programs is supported by nine Cancer Center Support Grant Shared Resources: Biostatistics and Computer Facility, Instrument Facility, Research Animal Facility, Histopathology Facility, In Vitro/Molecular Analysis Facility, Clinical Biochemistry Facility, Scientific Information and Editorial Facility, Biosafety and Biohazard Facility, and Organic Synthesis Facility. This Cancer Center Support Grant thus provides the necessary support for the interdisciplinary research activities of the American Health Foundation directed towards the understanding and prevention of cancer.

National Institute of Health (NIH)
National Cancer Institute (NCI)
Center Core Grants (P30)
Project #
Application #
Study Section
Cancer Center Support Review Committee (CCS)
Program Officer
Vembu, Devi
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
Institute for Cancer Prevention
United States
Zip Code
Rennert, Gad; Kremer, Ran; Rennert, Hedy S et al. (2015) Lower lung cancer rates in Jewish smokers in Israel and the USA. Int J Cancer 137:2155-62
Beyea, Jan; Stellman, Steven D; Teitelbaum, Susan et al. (2013) Imputation method for lifetime exposure assessment in air pollution epidemiologic studies. Environ Health 12:62
Boffetta, Paolo; Jayaprakash, Vijayvel; Yang, Ping et al. (2011) Tobacco smoking as a risk factor of bronchioloalveolar carcinoma of the lung: pooled analysis of seven case-control studies in the International Lung Cancer Consortium (ILCCO). Cancer Causes Control 22:73-9
Farooq, Umar; Joshi, Monika; Nookala, Vinod et al. (2010) Self-reported exposure to pesticides in residential settings and risk of breast cancer: a case-control study. Environ Health 9:30
Muscat, Joshua E; Stellman, Steven D; Caraballo, Ralph S et al. (2009) Time to first cigarette after waking predicts cotinine levels. Cancer Epidemiol Biomarkers Prev 18:3415-20
Stellman, Steven D; Djordjevic, Mirjana V (2009) Monitoring the tobacco use epidemic II: The agent: Current and emerging tobacco products. Prev Med 48:S11-5
Watanabe, Karen H; Djordjevic, Mirjana V; Stellman, Steven D et al. (2009) Incremental lifetime cancer risks computed for benzo[a]pyrene and two tobacco-specific N-nitrosamines in mainstream cigarette smoke compared with lung cancer risks derived from epidemiologic data. Regul Toxicol Pharmacol 55:123-33
Stellman, Steven D (2006) Ernst Wynder: a remembrance. Prev Med 43:239-45
El-Bayoumy, Karam; Sinha, Raghu (2004) Mechanisms of mammary cancer chemoprevention by organoselenium compounds. Mutat Res 551:181-97
Boyiri, Telih; Guttenplan, Joseph; Khmelnitsky, Michael et al. (2004) Mammary carcinogenesis and molecular analysis of in vivo cII gene mutations in the mammary tissue of female transgenic rats treated with the environmental pollutant 6-nitrochrysene. Carcinogenesis 25:637-43

Showing the most recent 10 out of 27 publications