The Behavioral and Field Research Core (BFRC) is designed to facilitate the integration of communication and behavioral research across the Institute including work in epidemiology, cancer prevention, clinical and developmental therapeutics, palliative care, and genetics. The BFRC is grouped in the Population Research Core Cluster along with the Epidemiology Research Core. The Core offers expertise in communication science and behavioral research methodologies; design and evaluation of evidence-based social and behavioral interventions (including social marketing as a systematic approach to population level behavior change); social network methodology and analysis; quality of life measurement utilizing the most appropriate instruments; ecological momentary assessment (EMA techniques provide methods by which a research participant can report on symptoms, affect, behavior, and cognitions proximal to the experience, and these reports are obtained many times throughout the study); electronic daily diaries (QOL continues to be a critical factor in developmental therapeutic trials); and community engagement research, particularly related to health disparities. The Core maintains an active network of community organization partnerships across the Institute's catchment area. Community partners participate in research advisory committees and community advisory committees, providing community perspective, input and facilitating access to the populations they serve. Through these partnerships, the Core facilitates community access for Institute researchers, thus serving to assist in the translation and dissemination of cancer research. Resources available through BFRC include real-time video recording and coding of clinical interactions (including equipment, software and expertise), access to an extensive video archive for communication and behavioral studies, geographical and population tracking/mapping capabilities, community research participant registries, access to comprehensive national datasets (e.g. HINTS), as well as an extensive bank of clinical and social/behavioral instruments and measures. The services provided by the BFRC have contributed to 32 peer-reviewed publications during the current review period. As an example, the BFRC provided all regulatory tasks, recruitment, data collection, video capture, post-production editing, and coding for Dr. Penner's (PSDR) work demonstrating the importance of recognizing and understanding how the distinct dynamics of racially concordant and discordant interactions affect medical encounters and outcomes, (Hagiwara N, Soc SciMed, 2013).

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National Cancer Institute (NCI)
Center Core Grants (P30)
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Subcommittee I - Transistion to Independence (NCI)
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Wayne State University
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Watza, Donovan; Purrington, Kristen S; Chen, Kang et al. (2017) Transcriptional programs of tumor infiltrating T-cells provide insight into mechanisms of immune response and new targets for immunotherapy. J Thorac Dis 9:4162-4164
Eggly, Susan; Hamel, Lauren M; Foster, Tanina S et al. (2017) Randomized trial of a question prompt list to increase patient active participation during interactions with black patients and their oncologists. Patient Educ Couns 100:818-826
Bao, Bin; Mitrea, Cristina; Wijesinghe, Priyanga et al. (2017) Treating triple negative breast cancer cells with erlotinib plus a select antioxidant overcomes drug resistance by targeting cancer cell heterogeneity. Sci Rep 7:44125
Bernardo, Margarida M; Dzinic, Sijana H; Matta, Maria J et al. (2017) The Opportunity of Precision Medicine for Breast Cancer With Context-Sensitive Tumor Suppressor Maspin. J Cell Biochem 118:1639-1647
Soave, Claire L; Guerin, Tracey; Liu, Jinbao et al. (2017) Targeting the ubiquitin-proteasome system for cancer treatment: discovering novel inhibitors from nature and drug repurposing. Cancer Metastasis Rev 36:717-736
Jones, Carissa C; Bush, William S; Crawford, Dana C et al. (2017) Germline Genetic Variants and Lung Cancer Survival in African Americans. Cancer Epidemiol Biomarkers Prev 26:1288-1295
Bosnyák, Edit; Michelhaugh, Sharon K; Klinger, Neil V et al. (2017) Prognostic Molecular and Imaging Biomarkers in Primary Glioblastoma. Clin Nucl Med 42:341-347
Ben Khedher, Soumaya; Neri, Monica; Papadopoulos, Alexandra et al. (2017) Menstrual and reproductive factors and lung cancer risk: A pooled analysis from the international lung cancer consortium. Int J Cancer 141:309-323
Tan, Zhijing; Nie, Song; McDermott, Sean P et al. (2017) Single Amino Acid Variant Profiles of Subpopulations in the MCF-7 Breast Cancer Cell Line. J Proteome Res 16:842-851
Embogama, D Maheeka; Pflum, Mary Kay H (2017) K-BILDS: A Kinase Substrate Discovery Tool. Chembiochem 18:136-141

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