): Planning and Evaluation: NCCC Planning and Evaluation applies external and internal assessment of capabilities and opportunities to the selection and subsequent pursuit of initiatives leading toward fulfillment of NCCC goals. The external process includes annual convening of distinguished External Advisors (EAC) for a review of the NCCC program. This comprehensive review is supplemented by consultation with visiting distinguished faculty, as well as targeted input from (1) external participants in our biannual Shared Resource reviews, (2) participation of a community representative on the NCCC Executive Committee, and (3) a semiannual meeting of corporate and community leaders on the Director's Board of Advisors. We have partnered with the New Hampshire Comprehensive Cancer Collaboration to identify and address catchment area needs. Internal planning and evaluation includes input from NCCC Members and is secured from regular meetings of NCCC Senior and Program Leadership, an annual center-wide retreat, and targeted seminars and symposia on key program developments. Weekly Grand Rounds and monthly Program meetings routinely provide opportunity for Members to present, hear, and comment on the status of current initiatives and the pending plans of individual projects. Standing forums for broader NCCC planning and evaluation discussions include the monthly NCCC Executive Committee, monthly Cancer Research Committee, semi-monthly Senior Leadership meetings, and weekly Senior Administrative meetings. NCCC Senior Leadership consolidates and publicizes their plans through annual updating and circulation of a five-year strategic plan. NCCC has developed opportunities to integrate into broader Dartmouth initiatives. There is extensive representation of NCCC Leadership in Dartmouth's CTSA (SYNERGY), including co-chair of the CTSA Internal Advisory Committee, and participation of the Director in senior leadership committees of the medical school and medical center. Application of planning considerations to current initiatives includes designation of targeted priorities for faculty recruitments, planning for use of the adjacent Williamson Translational Research Building under construction, the initiation of new Shared Resources and addition of new services, acquisition of major instrumentation, identifying and pursuing translational research opportunities, and investment of developmental funds and institutional resources into strategic priorities. Examples of capitalizing on EAC insights include recruitment in support of the expansion of Cancer Epidemiology into molecular epidemiology and the extensive new collaboration between NCCC and The Dartmouth Institute, in the health services delivery component of the Cancer Control Program, and NCCC's pursuit of an enhanced imaging research initiative in conjunction with the creation of the NCI-funded Center for Surgical Innovation. No new CCSG programs are proposed, but NCCC Members have secured an NCI-funded U54 in Cancer Nanotechnology, a U19 in EPR and dosimetry, and two new NIGMS Institutional Development (IDeA) P20 awards in molecular epidemiology and quantitative biomedical sciences.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA023108-40
Application #
9616810
Study Section
Subcommittee I - Transistion to Independence (NCI)
Project Start
Project End
Budget Start
2018-12-01
Budget End
2019-11-30
Support Year
40
Fiscal Year
2019
Total Cost
Indirect Cost
Name
Dartmouth College
Department
Type
DUNS #
041027822
City
Hanover
State
NH
Country
United States
Zip Code
03755
Shajani-Yi, Zahra; de Abreu, Francine B; Peterson, Jason D et al. (2018) Frequency of Somatic TP53 Mutations in Combination with Known Pathogenic Mutations in Colon Adenocarcinoma, Non-Small Cell Lung Carcinoma, and Gliomas as Identified by Next-Generation Sequencing. Neoplasia 20:256-262
Shee, Kevin; Jiang, Amanda; Varn, Frederick S et al. (2018) Cytokine sensitivity screening highlights BMP4 pathway signaling as a therapeutic opportunity in ER+ breast cancer. FASEB J :fj201801241R
Rodriguez-Garcia, Marta; Fortier, Jared M; Barr, Fiona D et al. (2018) Aging impacts CD103+ CD8+ T cell presence and induction by dendritic cells in the genital tract. Aging Cell 17:e12733
Pande, Mala; Joon, Aron; Brewster, Abenaa M et al. (2018) Genetic susceptibility markers for a breast-colorectal cancer phenotype: Exploratory results from genome-wide association studies. PLoS One 13:e0196245
Szczepiorkowski, Zbigniew M; Burnett, Christine A; Dumont, Larry J et al. (2018) Apheresis buffy coat collection without photoactivation has no effect on apoptosis, cell proliferation, and total viability of mononuclear cells collected using photopheresis systems. Transfusion 58:943-950
Bossé, Yohan; Amos, Christopher I (2018) A Decade of GWAS Results in Lung Cancer. Cancer Epidemiol Biomarkers Prev 27:363-379
Schmit, Stephanie L; Edlund, Christopher K; Schumacher, Fredrick R et al. (2018) Novel Common Genetic Susceptibility Loci for Colorectal Cancer. J Natl Cancer Inst :
Smith, T Jarrod; Sondermann, Holger; O'Toole, George A (2018) Co-opting the Lap System of Pseudomonas fluorescens To Reversibly Customize Bacterial Cell Surfaces. ACS Synth Biol 7:2612-2617
Gorlova, Olga Y; Li, Yafang; Gorlov, Ivan et al. (2018) Gene-level association analysis of systemic sclerosis: A comparison of African-Americans and White populations. PLoS One 13:e0189498
Moulton, Haley; Tosteson, Tor D; Zhao, Wenyan et al. (2018) Considering Spine Surgery: A Web-Based Calculator for Communicating Estimates of Personalized Treatment Outcomes. Spine (Phila Pa 1976) 43:1731-1738

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