Support is requested for planning and evaluation funds to support two major activities. The first is the visit of our External Advisory Committee. This committee visits the Center once per year to provide an evaluation of the Center's Programs and shared resources and to assist the Center in the planning process. Written reports are provided to the Director by the Committee. The reports are discussed with the Executive Committee and shared with the vice president for research. The second activity is the review of individual Center Programs. To facilitate planning and development of Center Programs, each is review every other year. The reviews are held contiguous with the External Advisory Committee annual meeting. Reviewers include one member from the External Advisory Committee and one outside reviewer for each program. This review involves an evaluation of the Program leadership, the research directions and progress of the program, and use of the Center's shared resources. The results of the Program reviews are presented to the External Advisory Committee at their meeting the following day. A written report of the review is provided to the director. Support is requested for one visit per year for seven External Advisory Committee members and two ad hoc program reviewers.
Planning and Evaluation provides direction to the Center and identifies needed areas of investigation. Leadership then provides resources to enhance discovery in the newly identified areas. New discoveries lead to new approaches for reducing the pain and suffering caused by cancer.
|Orellana, Esteban A; Tenneti, Srinivasarao; Rangasamy, Loganathan et al. (2017) FolamiRs: Ligand-targeted, vehicle-free delivery of microRNAs for the treatment of cancer. Sci Transl Med 9:|
|Wyatt-Johnson, Season K; Herr, Seth A; Brewster, Amy L (2017) Status Epilepticus Triggers Time-Dependent Alterations in Microglia Abundance and Morphological Phenotypes in the Hippocampus. Front Neurol 8:700|
|Han, Ning; Pang, Liang; Xu, Jun et al. (2017) Development of Surface-Variable Polymeric Nanoparticles for Drug Delivery to Tumors. Mol Pharm 14:1538-1547|
|Wu, M-J; Kim, M R; Chen, Y-S et al. (2017) Retinoic acid directs breast cancer cell state changes through regulation of TET2-PKC? pathway. Oncogene 36:3193-3206|
|Jang, Yumi; Rao, Xiayu; Jiang, Qing (2017) Gamma-tocotrienol profoundly alters sphingolipids in cancer cells by inhibition of dihydroceramide desaturase and possibly activation of sphingolipid hydrolysis during prolonged treatment. J Nutr Biochem 46:49-56|
|Li, Jie; Wang, Ruixin; Kong, Yifan et al. (2017) Targeting Plk1 to Enhance Efficacy of Olaparib in Castration-Resistant Prostate Cancer. Mol Cancer Ther 16:469-479|
|Wang, Siwen; Xing, Zheng; Pascuzzi, Pete E et al. (2017) Metabolic Adaptation to Nutrients Involves Coregulation of Gene Expression by the RNA Helicase Dbp2 and the Cyc8 Corepressor in Saccharomyces cerevisiae. G3 (Bethesda) 7:2235-2247|
|Yue, Feng; Bi, Pengpeng; Wang, Chao et al. (2017) Pten is necessary for the quiescence and maintenance of adult muscle stem cells. Nat Commun 8:14328|
|Li, Guo; Low, Philip S (2017) Synthesis and evaluation of a ligand targeting the ? and ? opioid receptors for drug delivery to lung cancer. Bioorg Med Chem Lett 27:2074-2078|
|Chen, I-Hsuan; Xue, Liang; Hsu, Chuan-Chih et al. (2017) Phosphoproteins in extracellular vesicles as candidate markers for breast cancer. Proc Natl Acad Sci U S A 114:3175-3180|
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