The NMR Shared Resource provides the infrastructure for the acquisition of NMR data and the determination of structures of biological molecules. The Varian INOVA 500-MHz NMR magnet, with its new console and probes are located in room 1009 of the Eppley Science Hall. The new Varian INOVA 600-MHz instrument is in the adjacent room (1010 ESH) and the two rooms have been connected with an opening. The 500-MHz NMR instrument has been upgraded with a new console and associated probes to make it state-of-the-art and compatible with the 600 instrument. A cold probe has been ordered for the 600 instrument, which will provide a significant increase in signal to noise and sensitivity. The facility is directed by Dr. Gus Wang (Assistant Professor, Eppley Institute, UNMC), with the support of Paul Keifer, Ph.D. (Research Assistant Professor, Eppley Institute), who maintains the infrastructure and provides user support. Cancer Center members with peer-reviewed funding account for 18% of the facility's usage.

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National Cancer Institute (NCI)
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Subcommittee G - Education (NCI)
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University of Nebraska Medical Center
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Gong, Qiang; Wang, Chao; Zhang, Weiwei et al. (2017) Assessment of T-cell receptor repertoire and clonal expansion in peripheral T-cell lymphoma using RNA-seq data. Sci Rep 7:11301
Tadros, Saber; Shukla, Surendra K; King, Ryan J et al. (2017) De Novo Lipid Synthesis Facilitates Gemcitabine Resistance through Endoplasmic Reticulum Stress in Pancreatic Cancer. Cancer Res 77:5503-5517
Romereim, Sarah M; Summers, Adam F; Pohlmeier, William E et al. (2017) Transcriptomes of bovine ovarian follicular and luteal cells. Data Brief 10:335-339
Lakshmanan, Imayavaramban; Salfity, Shereen; Seshacharyulu, Parthasarathy et al. (2017) MUC16 Regulates TSPYL5 for Lung Cancer Cell Growth and Chemoresistance by Suppressing p53. Clin Cancer Res 23:3906-3917
Hendershot, Jenna M; O'Brien, Patrick J (2017) Search for DNA damage by human alkyladenine DNA glycosylase involves early intercalation by an aromatic residue. J Biol Chem 292:16070-16080
Wu, Shaohua; Xu, Ranjie; Duan, Bin et al. (2017) Three-Dimensional Hyaluronic Acid Hydrogel-Based Models for In Vitro Human iPSC-Derived NPC Culture and Differentiation. J Mater Chem B 5:3870-3878
Wu, Shaohua; Wang, Ying; Streubel, Philipp N et al. (2017) Living nanofiber yarn-based woven biotextiles for tendon tissue engineering using cell tri-culture and mechanical stimulation. Acta Biomater 62:102-115
Roychoudhury, Shrabasti; Nath, Somsubhra; Song, Heyu et al. (2017) Human Apurinic/Apyrimidinic Endonuclease (APE1) Is Acetylated at DNA Damage Sites in Chromatin, and Acetylation Modulates Its DNA Repair Activity. Mol Cell Biol 37:
Trease, Andrew J; Capuccino, Juan M V; Contreras, Jorge et al. (2017) Intramolecular signaling in a cardiac connexin: Role of cytoplasmic domain dimerization. J Mol Cell Cardiol 111:69-80
Payne, William M; Hill, Tanner K; Svechkarev, Denis et al. (2017) Multimodal Imaging Nanoparticles Derived from Hyaluronic Acid for Integrated Preoperative and Intraoperative Cancer Imaging. Contrast Media Mol Imaging 2017:9616791

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