The mission of the Gene Expression Array Core Facility is to facilitate implementation of the latest methods in gene array technology in the research conducted at the Comprehensive Cancer Center of Case Western Reserve University (CWRU) and University Hospitals of Cleveland (UHC). The Core currently operates an Affymetrix GeneChip Processor and reader, prepares and processes samples, acquires data, and provides analytical services. The facility also assists with experimental design and provides consultation services to aid in selection, development, and utilization of appropriate data mining tools. The Core offers technical assistance and advice on all aspects of this new technology and sponsors a Users group, which meets regularly to review results in order to develop the most efficient exploitation of available microarray approaches. The Director and Manager conduct seminars to explain to new users the advantages and limitations of gene expression array technology. The Core also offers consultation to individual researchers to assist them in deciding whether expression microarray methodology may be brought to bear on their particular research questions. Further, the facility offers assistance in writing portions of grant applications which pertain to the use of gene array technology and provides letters of support to be included in grant applications.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
2P30CA043703-13
Application #
6548167
Study Section
Subcommittee E - Prevention &Control (NCI)
Project Start
1991-09-30
Project End
2006-07-31
Budget Start
Budget End
Support Year
13
Fiscal Year
2001
Total Cost
Indirect Cost
Name
Case Western Reserve University
Department
Type
DUNS #
077758407
City
Cleveland
State
OH
Country
United States
Zip Code
44106
Somasegar, Sahana; Li, Li; Thompson, Cheryl L (2018) No association of reproductive risk factors with breast cancer tumor grade. Eur J Cancer Prev 27:140-143
Gu, Xiaorong; Ebrahem, Quteba; Mahfouz, Reda Z et al. (2018) Leukemogenic nucleophosmin mutation disrupts the transcription factor hub that regulates granulomonocytic fates. J Clin Invest 128:4260-4279
Benson, Bryan L; Li, Lucy; Myers, Jay T et al. (2018) Biomimetic post-capillary venule expansions for leukocyte adhesion studies. Sci Rep 8:9328
Bosca, Federica; Bielecki, Peter A; Exner, Agata A et al. (2018) Porphyrin-Loaded Pluronic Nanobubbles: A New US-Activated Agent for Future Theranostic Applications. Bioconjug Chem 29:234-240
Cooper, Gregory S; Markowitz, Sanford D; Chen, Zhengyi et al. (2018) Evaluation of Patients with an Apparent False Positive Stool DNA Test: The Role of Repeat Stool DNA Testing. Dig Dis Sci 63:1449-1453
Morrow, James J; Bayles, Ian; Funnell, Alister P W et al. (2018) Positively selected enhancer elements endow osteosarcoma cells with metastatic competence. Nat Med 24:176-185
Anderson, Christian E; Wang, Charlie Y; Gu, Yuning et al. (2018) Regularly incremented phase encoding - MR fingerprinting (RIPE-MRF) for enhanced motion artifact suppression in preclinical cartesian MR fingerprinting. Magn Reson Med 79:2176-2182
Burger, Denis R; Parker, Yvonne; Guinta, Kathryn et al. (2018) PRO 140 Monoclonal Antibody to CCR5 Prevents Acute Xenogeneic Graft-versus-Host Disease in NOD-scid IL-2Rynull Mice. Biol Blood Marrow Transplant 24:260-266
Shi, Xiaojun; Wang, Bingcheng (2018) Caught in the ""Akt"": Cross-talk between EphA2 and EGFR through the Akt-PIKfyve axis maintains cellular sensitivity to EGF. Sci Signal 11:
Tartakoff, Alan Michael; Dulce, David; Landis, Elizabeth (2018) Delayed Encounter of Parental Genomes Can Lead to Aneuploidy in Saccharomyces cerevisiae. Genetics 208:139-151

Showing the most recent 10 out of 1227 publications