The Cancer Informatics Core (CIC) provides services, systems and tools to assist researchers In linking clinical phenotypes and other research data, with primary emphasis on: Clinical Informatics - Clinical informatics services through this core Include the identification, extraction, transformation, and interpretation of clinical data, whether captured as a part of routine care or through research activities. caBIG consulting and deployment - The CIC provides consulting services regarding caBIG technology and tools and also coordinates UMCCC's involvement with the caBIG program (for example, deploying caTISSUE to address issues associated with biospecimen repositories). Bioinformatics - Bioinformatics services include consulting on methodology and appropriate application of technology, a variety of analytical methods, and Integration of analysis from multiple experiments. The majority of the CIC's activities leverage larger IT-service providers in the University of Michigan Health System (UMHS). Although the CIC is small compared with the total UMHS IT staff (the CIC had 3 FTEs in 2010, and will grow to 9 in 2011, compared to more than 800 IT staff across UMHS), its effect is substantially magnified through leveraged Interactions with other, much larger existing resources. Accordingly, the CIC adheres to established and emerging standards and, where possible, uses software developed by national cooperative projects such as caBIG and the CTSAs. Many units in the UMHS offer IT services that can be used by UMCCC researchers. Although the CIC Is, in theory, a facility with a seven-year history, its current configuration is just over one year old.

Public Health Relevance

The Cancer Informatics Core provides highly specialized services, systems and tools to assist cancer researchers with analyzing large data sets used in basic, clinical and translational cancer research.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA046592-25
Application #
8559874
Study Section
Subcommittee G - Education (NCI)
Project Start
Project End
Budget Start
2013-06-01
Budget End
2014-05-31
Support Year
25
Fiscal Year
2013
Total Cost
$150,258
Indirect Cost
$65,865
Name
University of Michigan Ann Arbor
Department
Type
DUNS #
073133571
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
Hoban, Connor W; Beesley, Lauren J; Bellile, Emily L et al. (2018) Individualized outcome prognostication for patients with laryngeal cancer. Cancer 124:706-716
Maust, Joel D; Frankowski-McGregor, Christy L; Bankhead 3rd, Armand et al. (2018) Cyclooxygenase-2 Influences Response to Cotargeting of MEK and CDK4/6 in a Subpopulation of Pancreatic Cancers. Mol Cancer Ther 17:2495-2506
Arthur, Anna E; Goss, Amy M; Demark-Wahnefried, Wendy et al. (2018) Higher carbohydrate intake is associated with increased risk of all-cause and disease-specific mortality in head and neck cancer patients: results from a prospective cohort study. Int J Cancer 143:1105-1113
Valenciaga, Anisley; Saji, Motoyasu; Yu, Lianbo et al. (2018) Transcriptional targeting of oncogene addiction in medullary thyroid cancer. JCI Insight 3:
Akkina, Sarah R; Kim, Roderick Y; Stucken, Chaz L et al. (2018) Is There a Difference in Staging and Treatment of Head and Neck Squamous Cell Tumors Between Tertiary Care and Community-Based Institutions? Laryngoscope Investig Otolaryngol 3:290-295
Anwar, Talha; Arellano-Garcia, Caroline; Ropa, James et al. (2018) p38-mediated phosphorylation at T367 induces EZH2 cytoplasmic localization to promote breast cancer metastasis. Nat Commun 9:2801
Giraldez, Maria D; Spengler, Ryan M; Etheridge, Alton et al. (2018) Comprehensive multi-center assessment of small RNA-seq methods for quantitative miRNA profiling. Nat Biotechnol 36:746-757
Hartlerode, Andrea J; Regal, Joshua A; Ferguson, David O (2018) Reversible mislocalization of a disease-associated MRE11 splice variant product. Sci Rep 8:10121
Fritsche, Lars G; Gruber, Stephen B; Wu, Zhenke et al. (2018) Association of Polygenic Risk Scores for Multiple Cancers in a Phenome-wide Study: Results from The Michigan Genomics Initiative. Am J Hum Genet 102:1048-1061
Haley, Henry R; Shen, Nathan; Qyli, Tonela et al. (2018) Enhanced Bone Metastases in Skeletally Immature Mice. Tomography 4:84-93

Showing the most recent 10 out of 1493 publications